Organic Letters,
Journal Year:
2024,
Volume and Issue:
26(44), P. 9492 - 9497
Published: Oct. 30, 2024
Here
we
report
a
simultaneous
construction
of
two
C-C
and
C-N
bonds
in
unified
procedure
that
incorporates
alkynoic
acid
trifunctionalization,
ortho
C-H
functionalization,
amination
cascade.
In
an
ordered
process,
the
regioselective
alkyne
insertion
reaction
is
favored
over
decarboxylation
process.
The
presence
carboxyl
group
ensures
high
regioselectivity
carbopalladation
paving
way
for
novel
method
to
synthesize
unsymmetrically
2,3-diaryl
substituted
indole
scaffolds
with
excellent
regioselectivity.
protocol
demonstrated
be
suitable
gram-scale
synthesis.
Organometallics,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 26, 2025
The
rate,
site-selectivity,
and
product
isomerization
of
the
C(sp2)–H
oxidative
addition
arenes
with
pyridine(dicarbene)
cobalt
methyl
phenyl
complexes
have
been
investigated
four
representative
varying
electronic
steric
properties.
rates
activation
to
yield
cobalt-aryl
products
subsequent
aryl
were
influenced
by
properties
arene;
relatively
electron-poor
arene
3-fluorobenzotrifluoride
underwent
more
than
70
times
faster
electron-rich
substrate,
3-fluoro-N,N,α-trimethylbenzeneacetamide.
In
all
cases,
meta-to-fluorine
was
major
at
low
conversion,
which
subsequently
isomerized
ortho
isomer
over
time.
Deuterium-labeling
experiments
measurement
methane
isotopologues
establish
that
early
conversion
arises
from
kinetically
preferred,
meta-selective
addition.
Density
functional
theory
calculations
support
pathways
involving
cobalt(I)–(III)
redox
cycles
cobalt(I)
occurring
a
high
barrier
followed
reductive
elimination.
Despite
strong
σ-donating
pincer
ligand,
π-accepting
character
carbene
donors
lowers
for
elimination,
hence,
cobalt(III)
intermediates
not
observed.
Molecules,
Journal Year:
2025,
Volume and Issue:
30(8), P. 1711 - 1711
Published: April 11, 2025
Traditionally
employed
as
hydrogenation
reagents,
benzothiazolines
have
emerged
versatile
carbanion
and
radical
transfer
playing
a
vital
role
in
the
construction
of
various
carbon–carbon
bonds.
The
cutting-edge
progress
photochemistry
chemistry
prompted
study
visible
light-driven
reactions,
bringing
into
vibrant
focus.
Their
chemical
processes
been
uncovered
to
encompass
variety
activation
mechanisms,
with
five
distinct
modes
having
identified.
This
work
reviews
innovative
applications
donors
alkyl
or
acyl
groups,
achieving
hydroalkylation
hydroacylation
substitution.
By
examining
their
diverse
this
review
highlights
potential
serving
groups
for
further
research
development.
Moreover,
will
offer
exemplary
inspiration
synthetic
chemists,
contributing
ongoing
evolution
utility
organic
synthesis.
The Journal of Organic Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 11, 2025
A
palladium-catalyzed
decarboxylative
cross-coupling
of
zinc
polyfluorobenzoates
with
aryl
fluorosulfates,
which
proceeded
efficiently
via
C-O
bond
cleavage
to
afford
the
corresponding
polyfluorinated
biaryls
in
moderate-to-good
yields,
was
developed.
The
reactions
exhibited
both
good
substrate
scope
and
broad
functional
group
compatibility,
it
could
be
scaled-up
easily.
synthetic
simplicity
practicability
reaction
further
demonstrated
by
one-pot
manipulation
directly
mixing
polyfluorobenzoic
acid
Zn(OH)2
coexistence
fluorosulfate
a
palladium
catalyst
one
flask.
Further
studies
showed
that
is
more
robust
than
other
halides
pseudohalides
as
arylating
reagent,
polyfluorobenzoate
effective
polyfluoroarylating
agent
their
magnesium
potassium
counterparts.
Organic Letters,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 14, 2025
In
this
study,
we
developed
a
photoredox-catalyzed
defluorinative
cross-coupling
method
for
trifluoroketones
and
alkyl
boronic
acids.
The
reaction
afforded
series
of
novel
α,α-difluoroketone
derivatives,
in
vitro
fungicidal
activity
revealed
that
some
these
compounds
exhibited
moderate
to
excellent
against
Rhizoctonia
solani
Botrytis
cinerea.
particular,
compound
3d
showed
an
EC50
value
4.27
μg/mL
B.
cinerea
can
be
used
as
lead
further
optimization.
Inorganic Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 23, 2025
In
this
work,
Dy(NO3)3·6H2O
and
o-vanillin
reacted
under
"one-pot"
conditions,
achieving
for
the
first
time
four
efficient
condensations
of
obtaining
a
pair
chiral
hexanuclear
clusters
R/S-Dy6.
The
Dy(III)
ions
in
structure
R/S-Dy6
are
arranged
planar
quadrilateral
with
ion
derived
from
each
upper
lower
ends,
forming
shape
similar
to
"chair".
complex
ligands
H4LR1
H4LS1
were
obtained
simple
through
multistep
tandem
reaction.
Their
formation
process
involved
series
reaction
steps,
including
free
radical
coupling
form
pinacol
an
situ
o-vanillin.
Magnetic
studies
show
that
have
magnetic
anisotropy
and/or
low
excited
states.
addition,
has
outstanding
ability
produce
reactive
oxygen
species
low-power
light
irradiation
shows
excellent
photodynamic
sterilization.
inhibition
zones
against
Escherichia
coli
about
2.09
2.99
cm,
Staphylococcus
aureus
2.51
2.93
respectively.
This
work
not
only
provides
vivid
example
synthesis
organic
products
but
also
promotes
progress
lanthanide
clusters'
crystal
engineering.
Industrial & Engineering Chemistry Research,
Journal Year:
2024,
Volume and Issue:
63(34), P. 14983 - 15001
Published: Aug. 13, 2024
Compared
with
other
traditional
separation
technologies,
membrane
technologies
have
become
a
forefront
solution
to
looming
energy
and
environmental
issues
owing
their
significant
advantages,
e.g.,
low
consumption,
friendliness,
easy
operation,
high
efficiency.
Among
them,
fluorinated
was
special
material
fluorine
functional
groups,
which
is
endowed
properties
plays
key
role
in
specific
liquid
separation.
Due
the
electronegativity
of
atom
itself,
groups
formed
by
it
atoms
often
stability
physical
chemical
properties.
This
gives
excellent
antifouling
properties,
demonstrating
capabilities
for
enhancement
usage
lifetime
However,
there
lack
comprehensive
review
summarize
new
phase
progress
domain
membranes.
offers
overview
intricate
relationships
among
design
strategies,
functionalization,
preparation
methods
Furthermore,
generalizes
present
applications
membranes
including
pervaporation,
nanofiltration,
reverse
osmosis,
distillation,
oil–water
separation,
while
proposing
future
research
directions
challenges.
By
rational
analysis
methodologies,
structure
application
potential,
this
will
provide
reference
value
development
materials
fluoric
structure.
