Bio-Integrated Wearable Systems: A Comprehensive Review

Chemical Reviews, Journal Year: 2019, Volume and Issue: 119(8), P. 5461 - 5533

Published: Jan. 28, 2019

Bio-integrated wearable systems can measure a broad range of biophysical, biochemical, and environmental signals to provide critical insights into overall health status quantify human performance. Recent advances in material science, chemical analysis techniques, device designs, assembly methods form the foundations for uniquely differentiated type technology, characterized by noninvasive, intimate integration with soft, curved, time-dynamic surfaces body. This review summarizes latest this emerging field "bio-integrated" technologies comprehensive manner that connects fundamental developments chemistry, engineering sensing have potential widespread deployment societal benefit care. An introduction chemistries materials active components these contextualizes essential design considerations sensors associated platforms appear following sections. The subsequent content highlights most advanced biosensors, classified according their ability capture information. Additional sections feature schemes electrically powering strategies achieving fully integrated, wireless systems. concludes an overview key remaining challenges summary opportunities where chemistry will be critically important continued progress.

Language: Английский

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Selective Naked-Eye Detection of SARS-CoV-2 Mediated by N Gene Targeted Antisense Oligonucleotide Capped Plasmonic Nanoparticles

ACS Nano, Journal Year: 2020, Volume and Issue: 14(6), P. 7617 - 7627

Published: May 21, 2020

The current outbreak of the pandemic coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) demands its rapid, convenient, and large-scale diagnosis to downregulate spread within as well across communities. But reliability, reproducibility, selectivity majority such diagnostic tests fail when they are tested either a viral load at early representation or gene mutated during spread. In this regard, selective "naked-eye" detection SARS-CoV-2 is highly desirable, which can be without accessing any advanced instrumental techniques. We herein report development colorimetric assay based on gold nanoparticles (AuNPs), capped with suitably designed thiol-modified antisense oligonucleotides (ASOs) specific for N-gene (nucleocapsid phosphoprotein) SARS-CoV-2, could used diagnosing positive COVID-19 cases 10 min from isolated RNA samples. ASO-capped AuNPs agglomerate selectively in presence target sequence demonstrate change surface plasmon resonance. Further, addition RNaseH cleaves strand RNA-DNA hybrid leading visually detectable precipitate solution mediated additional agglomeration among AuNPs. has been monitored MERS-CoV limit 0.18 ng/μL having load. Thus, study reports visual causative virus, requirement sophisticated

Language: Английский

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Optical Sensing and Imaging of pH Values: Spectroscopies, Materials, and Applications

Chemical Reviews, Journal Year: 2020, Volume and Issue: 120(22), P. 12357 - 12489

Published: Nov. 4, 2020

This is the first comprehensive review on methods and materials for use in optical sensing of pH values applications such sensors. The Review starts with an introduction that contains subsections definition value, a brief look back pH, effects ionic strength pKa values, selectivity, sensitivity, precision, dynamic ranges, temperature dependence Commonly used schemes are covered next main chapter, based absorptiometry, reflectometry, luminescence, refractive index, surface plasmon resonance, photonic crystals, turbidity, mechanical displacement, interferometry, solvatochromism. followed by sections absorptiometric luminescent molecular probes Further large cover polymeric hosts supports, immobilization indicator dyes. more specific summarize state art dual functionality (indicator host), nanomaterials, sensors upconversion 2-photon absorption, multiparameter sensors, imaging, extreme values. A chapter many formats has planar, fiber optic, evanescent wave, resonance holography sensor designs, distributed sensing. Another section summarizes selected areas, as medicine, biology, oceanography, bioprocess monitoring, corrosion studies, transducers biosensors chemical their integration into flow-injection analyzers, microfluidic devices, lab-on-a-chip systems. An extra devoted to current challenges, challenges general nature those nature. concluding gives outlook potential future trends perspectives.

Language: Английский

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Recent Developments of Carbon Dots in Biosensing: A Review

ACS Sensors, Journal Year: 2020, Volume and Issue: 5(9), P. 2724 - 2741

Published: Aug. 19, 2020

Early diagnosis of diseases is great importance because it increases the chance a cure and significantly reduces treatment costs. Thus, development rapid, sensitive, reliable biosensing techniques essential for benefits human life health. As such, various nanomaterials have been explored to improve performance biosensors, among which, carbon dots (CDs) received enormous attention due their excellent performance. In this Review, recent advancements CD-based biosensors carefully summarized. First, are classified according sensing strategies, role CDs in these sensors elaborated detail. Next, several typical (including CD-only, enzymatic, antigen–antibody, nucleic acid biosensors) applications fully discussed. Last, advantages, challenges, perspectives on future trends highlighted.

Language: Английский

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Soil Sensors and Plant Wearables for Smart and Precision Agriculture

Advanced Materials, Journal Year: 2021, Volume and Issue: 33(20)

Published: April 7, 2021

Abstract Soil sensors and plant wearables play a critical role in smart precision agriculture via monitoring real‐time physical chemical signals the soil, such as temperature, moisture, pH, pollutants providing key information to optimize crop growth circumstances, fight against biotic abiotic stresses, enhance yields. Herein, recent advances of important soil agricultural applications, including temperature sensors, moisture organic matter compounds pH insect/pest pollutant are reviewed. Major sensing technologies, designs, performance, pros cons each sensor category highlighted. Emerging technologies wireless networks also discussed terms their applications agriculture. The research directions challenges intelligent finally presented.

Language: Английский

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Sensors for Volatile Organic Compounds

ACS Nano, Journal Year: 2022, Volume and Issue: 16(5), P. 7080 - 7115

Published: May 5, 2022

This paper provides an overview of recent developments in the field volatile organic compound (VOC) sensors, which are finding uses healthcare, safety, environmental monitoring, food and agriculture, oil industry, other fields. It starts by briefly explaining basics VOC sensing reviewing currently available quickly progressing approaches. then discusses main trends materials' design with special attention to nanostructuring nanohybridization. Emerging materials strategies highlighted their involvement different types technologies is discussed, including optical, electrical, gravimetric sensors. The review also detailed discussions about limitations offers potential solutions. status suggestions promising directions for future development summarized.

Language: Английский

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Graphene-Based Sensors for Human Health Monitoring

Frontiers in Chemistry, Journal Year: 2019, Volume and Issue: 7

Published: June 11, 2019

Since the desire for real-time human health monitoring as well seamless human-machine interaction is increasing rapidly, plenty of research efforts have been made to investigate wearable sensors and implantable devices in recent years. As a novel 2D material, graphene has aroused boom field sensor around world due its advantages mechanical, thermal, electrical properties. Numerous graphene-based used reported, including sensors, devices, which can realize measurement body temperature, heart rate, pulse oxygenation, respiration blood pressure, glucose, electrocardiogram signal, electromyogram electroencephalograph etc. Herein, review latest monitoring, their structures, sensing mechanisms, technological innovations, components systems potential challenges will be discussed outlined.

Language: Английский

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Artificial intelligence biosensors: Challenges and prospects

Biosensors and Bioelectronics, Journal Year: 2020, Volume and Issue: 165, P. 112412 - 112412

Published: July 4, 2020

Language: Английский

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Colorimetric sensor array based on gold nanoparticles: Design principles and recent advances

TrAC Trends in Analytical Chemistry, Journal Year: 2019, Volume and Issue: 122, P. 115754 - 115754

Published: Nov. 27, 2019

Language: Английский

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A review on chemiresistive ZnO gas sensors

Sensors and Actuators Reports, Journal Year: 2022, Volume and Issue: 4, P. 100100 - 100100

Published: April 10, 2022

Chemiresistive gas sensors have been widely applied to monitor analytes of environmental, food and health importance. Among the plethora materials that can be used for designing chemiresistive sensors, ZnO is one most explored sensing, as this material has a low-cost, non-toxic easily obtained through standard chemical synthesis. Adding this, form heterostructures capable improve sensor performance regarding sensitivity, selectivity stability. Moreover, also contribute lower operating temperature since synergistic effects amplify signal. In review, we survey recent advances on different types ZnO-based focusing how morphology structure these influence response. Challenges future perspectives are discussed.

Language: Английский

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