Chemical Reviews,
Journal Year:
2022,
Volume and Issue:
122(3), P. 3459 - 3636
Published: Jan. 7, 2022
Synthetic
molecular
probes,
chemosensors,
and
nanosensors
used
in
combination
with
innovative
assay
protocols
hold
great
potential
for
the
development
of
robust,
low-cost,
fast-responding
sensors
that
are
applicable
biofluids
(urine,
blood,
saliva).
Particularly,
metabolites,
neurotransmitters,
drugs,
inorganic
ions
is
highly
desirable
due
to
a
lack
suitable
biosensors.
In
addition,
monitoring
analysis
metabolic
signaling
networks
cells
organisms
by
optical
probes
chemosensors
becoming
increasingly
important
biology
medicine.
Thus,
new
perspectives
personalized
diagnostics,
theranostics,
biochemical/medical
research
will
be
unlocked
when
standing
limitations
artificial
binders
receptors
overcome.
this
review,
we
survey
synthetic
sensing
systems
have
promising
(future)
application
detection
small
molecules,
cations,
anions
aqueous
media
biofluids.
Special
attention
was
given
provide
readily
measurable
signal
through
dynamic
covalent
chemistry,
supramolecular
host-guest
interactions,
or
nanoparticles
featuring
plasmonic
effects.
This
review
shall
also
enable
reader
evaluate
current
performance
terms
sensitivity
selectivity
respect
practical
requirement,
thereby
inspiring
ideas
further
advanced
systems.
Small Science,
Journal Year:
2022,
Volume and Issue:
2(6)
Published: May 8, 2022
Carbon
dots
(CDs),
comprising
crystalline
graphitized
carbon
cores
and
polymer
surface
groups,
are
currently
attracting
a
lot
of
interest
in
biological
fields
owing
to
their
fluorescent
properties,
high
photostability,
biocompatibility
low
toxicity.
In
addition,
the
easy
preparation
functionalization
CDs
stimulate
development
CDs‐based
composite
materials
with
specific
functions.
Presently,
applications
growing
at
remarkable
speed,
justifying
need
for
up‐to‐date
review
articles
that
capture
recent
progress
this
blossoming
field.
review,
breakthroughs
synthesis,
modification,
optical
toxicology
biocatalytic
platforms
described.
Further,
research
related
bioimaging,
biosensing,
drug
delivery,
antibacterial,
anticancer
(photothermal
therapy,
photodynamic
therapy
synergistic
therapy)
antiviral
therapies
involving
discussed
detail.
Finally,
perspective
on
prospects
challenges
biomedicine
biotechnology
is
provided.
Small,
Journal Year:
2022,
Volume and Issue:
18(51)
Published: Nov. 3, 2022
Abstract
As
a
relatively
new
type
of
fluorescent
carbon‐based
nanomaterials,
multicolor
carbon
dots
(MCDs)
have
attracted
much
attention
because
their
excellent
biocompatibility,
tunable
photoluminescence
(PL),
high
quantum
yield,
and
unique
electronic
physicochemical
properties.
The
emission
characteristics
(CDs)
obviously
depend
on
the
source
precursor,
reaction
conditions,
environment,
which
directly
or
indirectly
determines
CDs.
Therefore,
this
review
is
first
systematic
classification
summary
multiple
regulation
methods
synthetic
MCDs
reviews
recent
research
progress
in
synthesis
from
variety
precursor
materials
such
as
aromatic
molecules,
small
organic
natural
biomass,
focusing
how
different
produce
corresponding
MCDs.
This
also
introduces
innovative
applications
fields
biological
imaging,
light‐emitting
diodes
(LEDs),
sensing,
anti‐counterfeiting
due
to
PL
It
hoped
that
by
selecting
appropriate
adjustment
methods,
can
inspire
guide
future
design
tailored
MCDs,
provide
help
for
development
multifunctional
Small,
Journal Year:
2022,
Volume and Issue:
18(16)
Published: Jan. 27, 2022
Abstract
Ultrasmall
nanoparticles
are
often
grouped
under
the
broad
umbrella
term
of
“nanoparticles”
when
reported
in
literature.
However,
for
biomedical
applications,
their
small
sizes
give
them
intimate
interactions
with
biological
species
and
endow
unique
functional
physiochemical
properties.
Carbon
quantum
dots
(CQDs)
an
emerging
class
ultrasmall
which
have
demonstrated
considerable
biocompatibility
been
employed
as
potent
theragnostic
platforms.
These
particles
find
application
increasing
drug
solubility
targeting,
along
facilitating
passage
drugs
across
impermeable
membranes
(i.e.,
blood
brain
barrier).
Further
functionality
can
be
triggered
by
various
environmental
conditions
or
external
stimuli
pH,
temperature,
near
Infrared
(NIR)
light,
ultrasound),
intrinsic
fluorescence
is
valuable
diagnostic
applications.
The
focus
this
review
to
shed
light
on
therapeutic
potential
CQDs
identify
how
they
travel
through
body,
reach
site
action,
administer
effect,
excreted.
Investigation
into
toxicity
compatibility
larger
nanoparticle
carriers
also
examined.
future
applications
promising
due
multifunctional
attributes
documented
biocompatibility.
As
nanomaterial
platforms
become
more
commonplace
clinical
treatments,
commercialization
CQD
therapeutics
anticipated.
Scientific Reports,
Journal Year:
2022,
Volume and Issue:
12(1)
Published: Aug. 15, 2022
Carbon
quantum
dots
(CQDs)
derived
from
biomass,
a
suggested
green
approach
for
nanomaterial
synthesis,
often
possess
poor
optical
properties
and
have
low
photoluminescence
yield
(PLQY).
This
study
employed
an
environmentally
friendly,
cost-effective,
continuous
hydrothermal
flow
synthesis
(CHFS)
process
to
synthesise
efficient
nitrogen-doped
carbon
(N-CQDs)
biomass
precursors
(glucose
in
the
presence
of
ammonia).
The
concentrations
ammonia,
as
nitrogen
dopant
precursor,
were
varied
optimise
CQDs.
Optimised
N-CQDs
showed
significant
enhancement
fluorescence
emission
with
PLQY
9.6%
compared
pure
glucose
derived-CQDs
(g-CQDs)
without
doping
which
less
than
1%.
With
stability
over
pH
range
2
11,
excellent
sensitivity
nano-sensor
highly
toxic
highly-pollutant
chromium
(VI),
where
(PL)
quenching
was
observed.
optimised
nitrogen-doping
demonstrated
effective
tuning
overall
electronic
structure
resulting
enhanced
performance
nano-sensor.
