Biomarker-activatable probes based on smart AIEgens for fluorescence and optoacoustic imaging DOI
Juan Ouyang, Lihe Sun, Fang Zeng

et al.

Coordination Chemistry Reviews, Journal Year: 2022, Volume and Issue: 458, P. 214438 - 214438

Published: Feb. 3, 2022

Language: Английский

Electronic Textiles for Wearable Point-of-Care Systems DOI

Guorui Chen,

Xiao Xiao, Xun Zhao

et al.

Chemical Reviews, Journal Year: 2021, Volume and Issue: 122(3), P. 3259 - 3291

Published: Dec. 23, 2021

Traditional public health systems are suffering from limited, delayed, and inefficient medical services, especially when confronted with the pandemic aging population. Fusing traditional textiles diagnostic, therapeutic, protective devices can unlock electronic (e-textiles) as point-of-care platform technologies on human body, continuously monitoring vital signs implementing round-the-clock treatment protocols in close proximity to patient. This review comprehensively summarizes research advances e-textiles for wearable systems. We start a brief introduction emphasize significance of current healthcare system. Then, we describe textile sensors diagnosis, therapeutic treatment, prevention, by highlighting their working mechanisms, representative materials, clinical application scenarios. Afterward, detail e-textiles' connection gateway real-time data transmission processing context 5G Internet Things. Finally, provide new insights into remaining challenges future directions field e-textiles. Fueled chemistry materials science, textile-based diagnostic devices, communication units expected interact synergistically construct intelligent, platforms, ultimately illuminating system Things era.

Language: Английский

Citations

513

Gas Sensors Based on Chemi-Resistive Hybrid Functional Nanomaterials DOI Creative Commons
Yingying Jian,

Wenwen Hu,

Zhenhuan Zhao

et al.

Nano-Micro Letters, Journal Year: 2020, Volume and Issue: 12(1)

Published: March 11, 2020

Abstract Chemi-resistive sensors based on hybrid functional materials are promising candidates for gas sensing with high responsivity, good selectivity, fast response/recovery, great stability/repeatability, room-working temperature, low cost, and easy-to-fabricate, versatile applications. This progress report reviews the advantages advances of these structures compared single constituent, according to five main forms: manipulating/constructing heterojunctions, catalytic reaction, charge transfer, carrier transport, molecular binding/sieving, their combinations. Promises challenges each form presented discussed. Critical thinking ideas regarding orientation development material-based sensor in future

Language: Английский

Citations

350

Multiplexed Nanomaterial-Based Sensor Array for Detection of COVID-19 in Exhaled Breath DOI Creative Commons

Benjie Shan,

Yoav Y. Broza,

Wenjuan Li

et al.

ACS Nano, Journal Year: 2020, Volume and Issue: 14(9), P. 12125 - 12132

Published: Aug. 18, 2020

This article reports on a noninvasive approach in detecting and following-up individuals who are at-risk or have an existing COVID-19 infection, with potential ability to serve as epidemic control tool. The proposed method uses developed breath device composed of nanomaterial-based hybrid sensor array multiplexed detection capabilities that can detect disease-specific biomarkers from exhaled breath, thus enabling rapid accurate diagnosis. An exploratory clinical study this was examined Wuhan, China, during March 2020. cohort included 49 confirmed patients, 58 healthy controls, 33 non-COVID lung infection controls. When applicable, positive patients were sampled twice: the active disease after recovery. Discriminant analysis obtained signals sensors achieved very good test discriminations between different groups. training set data exhibited respectively 94% 76% accuracy differentiating controls well 90% 95% other infections. While further validation studies needed, results may base for technology would lead reduction number unneeded confirmatory tests lower burden hospitals, while allowing screening solution be performed PoC facilities. considered platform could applied any proper modifications artificial intelligence therefore available diagnostic tool case new outbreak.

Language: Английский

Citations

350

Medical Micro/Nanorobots in Precision Medicine DOI Creative Commons
Fernando Soto, Jie Wang, Rajib Ahmed

et al.

Advanced Science, Journal Year: 2020, Volume and Issue: 7(21)

Published: Oct. 4, 2020

Advances in medical robots promise to improve modern medicine and the quality of life. Miniaturization these robotic platforms has led numerous applications that leverages precision medicine. In this review, current trends micro nanorobotics for therapy, surgery, diagnosis, imaging are discussed. The use nanorobots still faces technical, regulatory, market challenges their widespread clinical settings. Nevertheless, recent translations from proof concept vivo studies demonstrate potential toward

Language: Английский

Citations

324

Rational Design of Semiconductor‐Based Chemiresistors and their Libraries for Next‐Generation Artificial Olfaction DOI Creative Commons
Seong‐Yong Jeong, Jun‐Sik Kim, Jong‐Heun Lee

et al.

Advanced Materials, Journal Year: 2020, Volume and Issue: 32(51)

Published: Sept. 15, 2020

Abstract Artificial olfaction based on gas sensor arrays aims to substitute for, support, and surpass human olfaction. Like mammalian olfaction, a larger number of sensors more signal processing are crucial for strengthening artificial Due rapid progress in computing capabilities machine‐learning algorithms, on‐demand high‐performance that can eclipse becomes inevitable once diverse versatile sensing materials provided. Here, rational strategies design myriad different semiconductor‐based chemiresistors grow libraries enough identify wide range odors gases reviewed, discussed, suggested. Key approaches include the use p‐type oxide semiconductors, multinary perovskite spinel oxides, carbon‐based materials, metal chalcogenides, their heterostructures, as well heterocomposites distinctive utilization bilayer design, robust high‐throughput screening materials. In addition, state‐of‐the‐art key issues implementation electronic noses discussed. Finally, perspective chemiresistive next‐generation is

Language: Английский

Citations

302

Wearable chemical sensors for biomarker discovery in the omics era DOI Open Access
Juliane R. Sempionatto, José A. Lasalde‐Ramírez, Kuldeep Mahato

et al.

Nature Reviews Chemistry, Journal Year: 2022, Volume and Issue: 6(12), P. 899 - 915

Published: Nov. 15, 2022

Language: Английский

Citations

297

Sensors for Volatile Organic Compounds DOI
Muhammad Khatib, Hossam Haick

ACS Nano, Journal Year: 2022, Volume and Issue: 16(5), P. 7080 - 7115

Published: May 5, 2022

This paper provides an overview of recent developments in the field volatile organic compound (VOC) sensors, which are finding uses healthcare, safety, environmental monitoring, food and agriculture, oil industry, other fields. It starts by briefly explaining basics VOC sensing reviewing currently available quickly progressing approaches. then discusses main trends materials' design with special attention to nanostructuring nanohybridization. Emerging materials strategies highlighted their involvement different types technologies is discussed, including optical, electrical, gravimetric sensors. The review also detailed discussions about limitations offers potential solutions. status suggestions promising directions for future development summarized.

Language: Английский

Citations

278

MOF‐Based Chemiresistive Gas Sensors: Toward New Functionalities DOI
Young‐Moo Jo,

Yong Kun Jo,

Jong‐Heun Lee

et al.

Advanced Materials, Journal Year: 2022, Volume and Issue: 35(43)

Published: Aug. 10, 2022

The sensing performances of gas sensors must be improved and diversified to enhance quality life by ensuring health, safety, convenience. Metal–organic frameworks (MOFs), which exhibit an extremely high surface area, abundant porosity, unique chemistry, provide a promising framework for facilitating gas-sensor innovations. Enhanced understanding conduction mechanisms MOFs has facilitated their use as gas-sensing materials, various types have been developed examining the compositional morphological dependences implementing catalyst incorporation light activation. Owing inherent separation absorption properties catalytic activity, are applied molecular sieves, absorptive filtering layers, heterogeneous catalysts. In addition, oxide- or carbon-based materials with complex structures composites can derived appropriate post-treatment MOFs. This review discusses effective techniques design optimal MOFs, in terms computational screening synthesis methods. Moreover, through distinctive functionalities heterostructures, derivatives incorporated applications presented.

Language: Английский

Citations

231

Covalent organic frameworks as multifunctional materials for chemical detection DOI Creative Commons
Zheng Meng, Katherine A. Mirica

Chemical Society Reviews, Journal Year: 2021, Volume and Issue: 50(24), P. 13498 - 13558

Published: Jan. 1, 2021

Sensitive and selective detection of chemical biological analytes is critical in various scientific technological fields. As an emerging class multifunctional materials, covalent organic frameworks (COFs) with their unique properties modularity, large surface area, high stability, low density, tunable pore sizes functionalities, which together define programmable properties, show promise advancing detection. This review demonstrates the recent progress where COFs constitute integral component achieved function. highlights how can be harnessed to develop different types systems based on principles chromism, luminescence, electrical transduction, chromatography, spectrometry, others achieve highly sensitive analytes, ranging from gases, volatiles, ions, biomolecules. The key parameters performance for target are summarized, compared, analyzed perspective mechanism structure-property-performance correlations COFs. Conclusions summarize current accomplishments analyze challenges limitations that exist under mechanisms. Perspectives future directions research advance COF-based through innovation novel COF design synthesis, device fabrication, exploration modes also discussed.

Language: Английский

Citations

209

Cancer diagnosis with DNA molecular computation DOI
Chao Zhang, Yumeng Zhao, Xuemei Xu

et al.

Nature Nanotechnology, Journal Year: 2020, Volume and Issue: 15(8), P. 709 - 715

Published: May 25, 2020

Language: Английский

Citations

198