Degradation of organophosphate flame retardants by white-rot fungi: Degradation pathways and associated toxicity

The Science of The Total Environment, Journal Year: 2025, Volume and Issue: 959, P. 178260 - 178260

Published: Jan. 1, 2025

The environmental persistence of organophosphate flame retardants (OPFRs) in water is becoming and concern. White Rot Fungi (WRF) have proven its capability to degrade certain OPFRs such as tributyl phosphate (TBP), tris(2-butoxyethyl) (TBEP), tris(2-chloroethyl) (TCEP) tris(2-chloroisopropyl) (TCPP). Despite this capability, there limited knowledge about the specific pathways involved degradation. In study, three different WRF were paired with individual OPFRs, potential transformation products (TPs) identified by UHPLC-HRMS. Some compounds structures further validated NMR. From these data degradation proposed. TBP was degraded successive hydroxylation hydrolysis reactions, a novel dehydrogenation step suggested. Both TCEP TCPP underwent oxidative dechlorination, experiencing subsequent hydrolysis. Uncommon reductive dehalogenation also observed. environmentally relevant methylation. TBEP generated numerous TPs, mainly dealkylations, along hydroxylation. Notably, demethylation proposed for first time. Additional secondary formed through oxidation initial metabolites. Finally, vivo silico toxicity assessments conducted, identifying TPs potentially toxic.

Language: Английский

Environmental Safety Perspectives on Organophosphate Flame Retardants: Current strategies and advancements in their environmental removal and detection

Journal of environmental chemical engineering, Journal Year: 2025, Volume and Issue: unknown, P. 115340 - 115340

Published: Jan. 1, 2025

Language: Английский

Spatial variation, emissions, transport, and risk assessment of organophosphate esters in two large petrochemical complexes in southern China

Journal of Environmental Management, Journal Year: 2024, Volume and Issue: 367, P. 122106 - 122106

Published: Aug. 6, 2024

Language: Английский