The microbiome orchestrates contaminant low-dose phytostimulation DOI
Evgenios Agathokleous, Edward J. Calabrese, Stavros D. Veresoglou

et al.

Trends in Plant Science, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

Language: Английский

Hepatotoxicity in Carp (Carassius auratus) Exposed to Perfluorooctane Sulfonate (PFOS): Integrative Histopathology and Transcriptomics Analysis DOI Creative Commons
Lin Tang,

Guijie Hao,

Dongren Zhou

et al.

Animals, Journal Year: 2025, Volume and Issue: 15(4), P. 610 - 610

Published: Feb. 19, 2025

Perfluorooctane sulfonate (PFOS) contamination poses a significant environmental threat due to its widespread distribution and persistence. However, the hepatotoxic effects of PFOS on key aquatic species, such as crucian carp, remain understudied. This study systematically investigated hepatotoxicity underlying molecular mechanisms associated with exposure in carp over 21 day period. We determined 96 h 50% lethal concentration (LC50) 23.17 mg/L. Histopathological transcriptomic analyses confirmed PFOS-induced liver damage characterized by venous congestion, nucleolar dissolution cellular vacuolation. Transcriptomic profiling further identified 1036 differentially expressed genes (DEGs), involving critical pathways related lipid energy metabolism, immunity, endocrine regulation. These are integral development nonalcoholic fatty disease (NAFLD). Specifically, DEGs metabolism showed changes, while those involved indicated disrupted ATP production mitochondrial function. Genes immune response revealed an upregulation pro-inflammatory markers, hormone regulation highlighted alterations signaling. Our findings emphasized that exhibits acute toxicity potentially inducing disrupting multiple physiological systems. research provides theoretical foundation for mitigating pollution protecting eco-health, contributing broader ecological conservation biology discussions.

Language: Английский

Citations

1
Evanescent hormesis effect induced by environmentally related PFOS to marine Chlorella sp DOI
Xiaofeng Li, Zhiguang Niu,

Meiqi Jing

et al.

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 480, P. 136115 - 136115

Published: Oct. 9, 2024

Language: Английский

Citations

3
Cellular and individual toxicity of diflubenzuron for the chronic exposure in Daphnia magna: focus on oxidative stress, chitin content, and reproductive outcomes DOI

Gunay Karimova,

Joorim Na,

Gersan An

et al.

Ecotoxicology, Journal Year: 2025, Volume and Issue: unknown

Published: May 15, 2025

Language: Английский

Citations

0
Bioaccumulation and bioelimination of per-and polyfluoroalkyl substances in aquatic organisms: a review DOI
Qun Yu, Leilei Cai, Huaqing Liu

et al.

Journal of Water Process Engineering, Journal Year: 2025, Volume and Issue: 75, P. 108065 - 108065

Published: June 1, 2025

Language: Английский

Citations

0
When subcellular chemical imaging enlightens our understanding on intestinal absorption, intracellular fate and toxicity of PFOA in vitro DOI Creative Commons
Charlotte Stoffels, Sébastien Cambier, Maria Angels Subirana

et al.

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 480, P. 136205 - 136205

Published: Oct. 18, 2024

Language: Английский

Citations

2
The microbiome orchestrates contaminant low-dose phytostimulation DOI
Evgenios Agathokleous, Edward J. Calabrese, Stavros D. Veresoglou

et al.

Trends in Plant Science, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

Language: Английский

Citations

1