Advances in Wastewater-Based Epidemiology for Pandemic Surveillance: Methodological Frameworks and Future Perspectives

Microorganisms, Journal Year: 2025, Volume and Issue: 13(5), P. 1169 - 1169

Published: May 21, 2025

Wastewater-based epidemiology (WBE) has emerged as a transformative approach for community-level health monitoring, particularly during the COVID-19 pandemic. This review critically examines methodological framework of WBE systems through following three core components: (1) sampling strategies that address spatial–temporal variability in wastewater systems, (2) comparative performance different platforms pathogen detection, and (3) predictive modeling integrating machine learning approaches. We systematically analyze how these components collectively overcome limitations conventional surveillance methods early outbreak asymptomatic case identification, population-level trend monitoring. While highlighting technical breakthroughs viral concentration variant tracking sequencing, also identifies persistent challenges, including data standardization, cost-effectiveness concerns resource-limited settings, ethical considerations public surveillance. Drawing insights from global implementation cases, we propose recommendations optimizing each operational phase discuss emerging applications beyond pandemic response. highlights an indispensable tool modern health, whose refinements cross-disciplinary integration are critical transforming reactive containment to proactive population management.

Language: Английский

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Wastewater-based epidemiology of influenza viruses: a systematic review

The Science of The Total Environment, Journal Year: 2025, Volume and Issue: 986, P. 179706 - 179706

Published: May 30, 2025

Language: Английский

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Notes from the Field: The National Wastewater Surveillance System’s Centers of Excellence Contributions to Public Health Action During the Respiratory Virus Season — Four U.S. Jurisdictions, 2022–23

MMWR Morbidity and Mortality Weekly Report, Journal Year: 2023, Volume and Issue: 72(48), P. 1309 - 1312

Published: Nov. 30, 2023

Language: Английский

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A systematic review of influenza virus in water environments across human, poultry, and wild bird habitats

Water Research X, Journal Year: 2023, Volume and Issue: 22, P. 100210 - 100210

Published: Dec. 13, 2023

Influenza, a highly contagious acute respiratory disease, remains major global health concern. This study aimed to comprehensively assess the prevalence of influenza virus in different aquatic environments. Using 43 articles from four databases, we thoroughly examined water matrices wastewater treatment plants (WTPs) and other human environments, as well poultry habitats areas frequented by migratory wild birds. In WTP influents (10 studies), positivity rates for A ranged 0.0% 97.6%. For B (8 most studies reported no positivity, except three reporting detection 0.8%, 5.6%, 46.9% samples. Within (13 4.2% 76.4%, while environments birds (11 it 0.4% 15.1%. Geographically, were distributed follows: 39.5% Americas, 18.6% Europe, 2.3% South-East Asia Western Pacific. Several subtypes found matrices, including avian (H3N6, H3N8, H4N1, H4N2, H4N6, H4N8, H5N1, H5N8, H6N2, H6N6, H7N9, H0N8, H11N9) seasonal (H1N1 H3N2). The existing literature indicates crucial requirement more extensive future research on this issue. Specifically, emphasizes need method harmonization delves into deserving in-depth such pertaining pig farming low-income countries.

Language: Английский

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The impact of trained immunity in respiratory viral infections

Reviews in Medical Virology, Journal Year: 2024, Volume and Issue: 34(1)

Published: Jan. 1, 2024

Abstract Epidemic peaks of respiratory viruses that co‐circulate during the winter‐spring seasons can be synchronous or asynchronous. The occurrence temporal patterns in epidemics caused by some suggests they could negatively interact with each other. These negative interactions may result from a programme innate immune memory, known as trained immunity, which confer broad protective effects against viruses. It is suggested stimulation cells vaccine pathogen induce their long‐term functional reprogramming through an interplay between metabolic and epigenetic changes, influence transcriptional response to secondary challenge. During coronavirus disease 2019 pandemic, circulation most was prevented non‐pharmacological interventions then resumed at unusual periods once sanitary measures were lifted. With time, should find again own ecological niches. This transition period provides opportunity study population level.

Language: Английский

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