Organic Peroxides in Transition-Metal-Free Cyclization and Coupling Reactions (C–C) via Oxidative Transformation
ACS Omega,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 14, 2025
Transition-metal-free
transformations
are
recognized
as
green
and
sustainable
methods
for
constructing
carbon-carbon
bonds
in
organic
synthesis.
This
review
describes
the
application
of
six
peroxides,
including
tert-butyl
hydroperoxide
(TBHP),
di-tert-butyl
peroxide
(DTBP),
peroxybenzoate
(TBPB),
benzoyl
(BPO),
dialauroyl
(DLP),
diguyl
(DCP),
C-C
bond
construction,
highlighting
selected
examples
mechanisms
challenging
transformations.
Each
section
concludes
with
a
detailed
overview
suitable
reagents
various
coupling
reactions
strengths
weaknesses
reported
works.
work
aims
to
inspire
further
innovations
transition-metal-free
oxidative
transformations,
promoting
eco-friendly
chemical
processes
paving
way
new
peroxide-based
synthesis
methods.
Language: Английский
Emerging investigator series: The gas phase ozonolysis and secondary OH production of cashmeran, a musk compound from fragrant volatile chemical products
Environmental Science Processes & Impacts,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Jan. 1, 2024
Fragrant
personal
care
products
are
a
subset
of
volatile
chemical
(VCPs),
an
emerging
source
outdoor
pollutants
capable
impacting
air
quality.
molecules,
such
as
musks,
used
in
perfumes
and
have
been
found
aquatic
organisms,
water
bodies,
indoor
air,
urban
environments.
Considering
the
distribution
musk-smelling
compounds,
there
is
need
to
constrain
their
atmospheric
fate
indoors
outdoors.
Here,
we
Vocus
proton-transfer-reaction
time-of-flight
mass
spectrometer
quantify
oxidative
cashmeran,
bicyclic
musk
compound,
detected
commercial
perfume
alongside
galaxolide,
astratone
rosamusk.
Cashmeran
concentrations
rose
up
0.35
ppbv
representing
yield
0.33
±
0.04%
perfume.
We
determined
second
order
rate
constant
cyclo-addition
O
Language: Английский