Molecules,
Journal Year:
2019,
Volume and Issue:
24(2), P. 334 - 334
Published: Jan. 18, 2019
The
reliable
and
efficient
production
of
radioisotopes
for
diagnosis
therapy
is
becoming
an
increasingly
important
capability,
due
to
their
demonstrated
utility
in
Nuclear
Medicine
applications.
Starting
from
the
first
processes
involving
separation
99mTc
irradiated
materials,
several
methods
concepts
have
been
developed
selectively
extract
interest.
Even
though
initial
were
based
on
liquid-liquid
extraction
(LLE)
approaches,
perceived
difficulty
automating
such
has
slowly
moved
focus
towards
resin
methods,
whose
basic
chemical
principles
are
often
similar
LLE
ones
terms
chelators
phases.
However,
emerging
field
flow
chemistry
allows
be
easily
automated
operated
a
continuous
manner,
resulting
even
improved
efficiency
reliability.
In
this
contribution,
we
will
outline
fundamentals
translation
into
flow-based
apparatuses;
addition,
provide
examples
radioisotope
separations
that
achieved
using
methods.
This
article
intended
offer
insights
about
future
potential
purify
medically
relevant
radioisotopes.
Industrial & Engineering Chemistry Research,
Journal Year:
2021,
Volume and Issue:
60(14), P. 5049 - 5075
Published: March 31, 2021
The
ability
of
small
and
microchannels
to
enhance
mass
transfer,
reduce
diffusional
limitations,
create
a
safer
process
has
made
them
the
best
choice
for
intensification.
This
study
provides
review
available
experimental
computational
literature
on
hydrodynamics
liquid–liquid
two-phase
flow
in
microscale,
namely,
regimes,
pressure
drop,
structure.
When
two
immiscible
liquids
channels,
various
patterns
can
be
observed,
with
development
those
being
influenced
by
several
parameters,
such
as
geometry
mixing
junction
channel,
channel
material,
fluids
properties,
orientation
flow.
As
part
observations
measurement,
velocity
fields
internal
circulation
reported
were
reviewed
context
microparticle
velocimetry
(μPIV)
implementation.
Also,
relevant
our
is
outlining,
models
that
have
been
used
predict
it.
These
are
discussed
detail
special
reference
viscosities.
Moreover,
numerical
studies
results
using
fluid
dynamics
(CFD)
also
discussed,
terms
validity
simulation
different
parameters
affecting
slug
formation
patterns.
Each
section
discussion
points
out
gaps
research
proposes
future
work
could
further
develop
technology
under
microchannels.
Journal of Separation Science,
Journal Year:
2023,
Volume and Issue:
46(15)
Published: June 3, 2023
Miniaturization
of
the
analytical
process
has
been
a
widespread
trend,
and
sample
preparation
stage
is
not
exempted
from
this
downscaling.
Since
introduction
microextraction
techniques
as
miniaturization
classical
extraction
techniques,
they
have
become
one
strengths
in
field.
However,
some
original
approaches
to
these
did
fully
cover
all
current
principles
Green
Analytical
Chemistry.
For
reason,
during
last
years,
much
emphasis
placed
on
reducing/eliminating
toxic
reagents,
reducing
amount
phase,
searching
for
new
greener,
more
selective
extractant
materials.
On
other
hand,
even
though
high
accomplishments
achieved,
same
attention
always
paid
sample,
which
essential
when
treating
low‐availability
samples
such
biological
samples,
or
developing
portable
devices.
In
review,
we
intend
give
readership
an
overview
advances
toward
further
techniques.
Finally,
brief
reflection
made
terminology
used,
that
should,
our
opinion,
be
used
term
generation
miniaturized
approaches.
To
regard,
term,
‘ultramicroextraction’
proposed
refer
those
beyond
microextraction.
Analytical Chemistry,
Journal Year:
2018,
Volume and Issue:
90(14), P. 8345 - 8353
Published: May 7, 2018
Microfluidic
devices
provide
ideal
environments
to
study
solvent
extraction.
When
droplets
form
and
generate
plug
flow
down
the
microfluidic
channel,
device
acts
as
a
microreactor
in
which
kinetics
of
chemical
reactions
interfacial
transfer
can
be
examined.
Here,
we
present
methodology
that
combines
chemometric
analysis
with
online
micro-Raman
spectroscopy
monitor
biphasic
extractions
within
device.
Among
many
benefits
microreactors
is
ability
maintain
small
sample
volumes,
especially
important
when
studying
extraction
harsh
environments,
such
separations
related
nuclear
fuel
cycle.
In
extraction,
efficiency
process
depends
on
complex
formation
rates
systems.
Thus,
it
understand
kinetic
parameters
an
system
high
effectivity
process.
This
monitoring
provided
concentration
measurements
both
organic
aqueous
plugs
they
were
pumped
through
channel.
The
studied
was
comprised
HNO3
phase
30%
(v/v)
tributyl
phosphate
n-dodecane
phase,
simulated
plutonium
uranium
reduction
(PUREX)
Using
pre-equilibrated
solutions
(post
extraction),
validity
technique
illustrated.
Following
this
validation,
not
equilibrated
examined
mass
established.
Kinetic
results
compared
already
determined
macro
scale
prove
efficacy
technique.
The Canadian Journal of Chemical Engineering,
Journal Year:
2021,
Volume and Issue:
100(2), P. 325 - 348
Published: Feb. 11, 2021
Abstract
Two‐phase
Taylor
flow
has
received
considerable
attention
from
researchers
in
recent
decades
due
to
its
potential
use
a
wide
variety
of
industrial
and
medical
applications.
A
large
number
experimental,
analytical,
numerical
efforts
have
been
taken
by
understand
the
fundamental
characteristics
two‐phase
flows
relevant
transport
phenomena.
This
paper
presents
comprehensive
review
hydrodynamics,
pattern,
liquid
film
thickness
through
mini‐
microchannels
with
different
cross‐sectional
geometry.
also
reviews
correlations
that
predict
for
gas‐liquid
liquid‐liquid
flows.
The
variations
are
plotted
over
range
capillary
numbers
both
experimental
computational
studies.
study
shows
effects
area
on
patterns
not
sufficiently
investigated
researchers,
particularly
rectangular
areas
aspect
ratios.
