Phytochemical Analysis,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 26, 2025
Peels
are
an
abundant
but
still
underutilized
waste
product
in
the
Citrus
fruit
industry.
They
contain
coumarins
with
antiadipogenic
potential
that
could
be
promising
targets
new
valorization
strategies
for
peels.
In
this
study,
these
coumarins,
is,
citropten,
bergamottin,
and
5-geranyloxy-7-methoxycoumarin
(5G7MC),
were
investigated
limon
peels
of
different
commercial
varieties
by
HPLC-DAD
after
extraction
ethanol
choline
chloride-based
natural
deep
eutectic
solvents
(NADES)
as
alternative
agents
green
extraction.
Target
almost
exclusively
found
flavedo
(exocarp)
peel
layer
whole
samples,
not
albedo
(mesocarp)
layer.
Flavedo
samples
from
"Verdelli"
(ES)
"Lisbon"
(ZA)
showed
particularly
high
concentrations
ethanolic
extracts.
When
applying
NADES
extraction,
best
results
citropten
achieved
malonic
acid,
1,2-propanediol,
citric
acid
hydrogen
bond
donors
(HBDs),
higher
yields
than
reference
solvent
ethanol.
For
bergamottin
5G7MC,
obtained
1,2-propanediol
HBD,
though
lower
The
possible
chlorination
coumarin
epoxides
byakangelicol
oxypeucedanin
was
recognized
acidic
LC-MS
analysis.
Overall,
C.
proved
to
a
relevant
starting
material
through
NADES.
Catalysis Reviews,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 126
Published: April 8, 2024
Monoterpenes
derived
from
various
biomass
constitute
an
important
platform
for
synthesizing
fragrances,
intermediates,
and
pharmaceuticals.
In
this
review,
the
most
recent
relevant
transformations
of
terpenes
are
discussed
with
primary
focus
on
heterogeneous
catalysis
emphasizing
green
chemistry
chemical
engineering
aspects.
This
review
aims
to
outline
significant
advancements
in
particular
importance
academic
industrial
research.
is
accomplished
by
highlighting
pivotal
reactions,
including
oxidation,
epoxidation,
hydroformylation,
CO2
cycloaddition,
isomerization,
condensation,
one-pot
synthesis
(such
as
tandem
telescopic
reactions),
using
catalytic
routes
that
have
been
published
literature
last
decade.
The
provides
insights
catalyst
design
mentioned
above
tailoring
selectivity
highlights
structure–activity
relationship.
Pharmaceuticals,
Journal Year:
2024,
Volume and Issue:
17(3), P. 355 - 355
Published: March 9, 2024
The
methods
and
solvents
employed
in
routine
extraction
protocols
essentially
impact
the
composition
of
resulting
extracts,
i.e.,
relative
abundances
individual
biologically
active
metabolites
quality
stability
isolates.
Natural
deep
eutectic
(NADESs)
represent
a
new
class
environmentally
friendly
solvents,
which
are
recognized
as
promising
extractants
alternative
to
conventional
organic
liquids.
However,
their
efficiencies
when
applied
different
workflows
still
poorly
characterized.
Therefore,
here,
we
compare
potential
three
for
natural
products
from
Aralia
elata
var.
mandshurica
with
selected
using
non-targeted
metabolomics
approach.
metabolite
profiling
relied
on
reversed-phase
ultra-high-performance
liquid
chromatography–high-resolution
mass
spectrometry
(RP-UHPLC-HR-MS).
roots
A.
were
extracted
by
maceration,
ultrasound-assisted
(UAE),
vibrocavitation-assisted
(VAE).
Principal
component
analysis
(PCA)
revealed
clear
separation
extracts
obtained
NADES1
(choline
chloride/malic
acid)
NADES2
(sorbitol/malic
acid/water).
Based
results
hierarchical
clustering
normalized
further
statistical
evaluation
t-test,
it
could
be
concluded
that
showed
superior
efficiency
all
addressed.
this
NADES
was
more
detail.
PCA
followed
t-test
yielded
only
3
efficiently
whereas
46
compounds
abundant
VAE.
When
VAE
UAE
compared,
108
appeared
VAE,
1
recovered
UAE.
These
facts
clearly
indicate
advantage
method
over
maceration
Seven
twenty-seven
tentatively
identified
tandem
(MS/MS)
found
first
time.
Additional
studies
necessary
understand
applicability
other
plant
materials.
Separation Science and Technology,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 27
Published: Jan. 15, 2025
The
sustainable
extraction
of
natural
antioxidants
from
plants
has
gained
significant
attention
as
a
viable
alternative
to
synthetic
options
in
the
food
industry.
However,
traditional
processes
often
rely
on
hazardous
solvents,
raising
concerns
about
toxicity
and
environmental
impact.
This
review
highlights
transformative
potential
green
solvents
innovative
technologies
advancing
practices
aligned
with
Sustainable
Development
Goals.
Key
findings
include
effectiveness
intensification
techniques,
such
ultrasound-assisted
microwave-assisted
extractions,
enhancing
efficiency
reducing
resource
use.
also
explores
solutions
critical
challenges
like
solvent
recovery
recycling,
promising
approaches
biphasic
systems
situ
methods
demonstrating
industrial
feasibility.
Notably,
this
work
bridges
gap
between
laboratory-scale
research
large-scale
production
by
emphasizing
strategies
improve
process
scalability.
By
synthesizing
current
trends
identifying
future
directions,
offers
unique
insights
into
commercially
for
antioxidant
extraction,
positioning
essential
tools
more
