Naturally‐occurring nematicides of plant origin: two decades of novel chemistries DOI Creative Commons
H. Ibrahim, Vaderament‐A. Nchiozem‐Ngnitedem, Louise‐Marie Dandurand

et al.

Pest Management Science, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 6, 2024

Abstract Plant‐parasitic nematodes are among the most destructive plant pathogens, resulting in a global annual economic loss of about 358 billion dollars. Using synthetic nematicides to control plant‐parasitic has resulted broad‐spectrum toxicity environment. Plant‐derived secondary metabolites have recently emerged as viable options that provide effective, greener, and renewable routes for managing various cropping systems. However, limited comprehensive information on plant‐derived sources, chemical structures, nematicidal activities is available. This study aims compile analyze data plant‐based with properties collected over last two decades. In this review, we identified 262 were isolated from 35 families 65 species. Alkaloids, terpenoids, saponins, flavonoids, coumarins, thiophenes, annonaceous acetogenins studied compounds. addition structure–activity relation specific potency, techniques their extraction isolation material discussed. Our findings demonstrate potential plants feedstock sourcing compounds discovering new chemistries could potentially be used developing next generation nematicides. © 2024 The Author(s). Pest Management Science published by John Wiley & Sons Ltd behalf Society Chemical Industry.

Language: Английский

Antioxidant and antimicrobial activities of different extracts of Tragopogon dubius and Tragopogon porrifolium L. subsp. longirostris: Determination of their phytochemical contents by UHPLC-Orbitrap®-HRMS analysis DOI
İnan Dursun, Rüya Sağlamtaş, Kübra FETTAHOĞLU

et al.

Food Bioscience, Journal Year: 2024, Volume and Issue: unknown, P. 105604 - 105604

Published: Dec. 1, 2024

Language: Английский

Citations

6
Physicochemical and Antimicrobial Properties of Lactic Acid-Based Natural Deep Eutectic Solvents as a Function of Water Content DOI Creative Commons
Olga N. Pozharitskaya, Ekaterina D. Obluchinskaya, Veronika A. Shikova

et al.

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(22), P. 10409 - 10409

Published: Nov. 12, 2024

The interest in natural deep eutectic solvents (NADESs) green technology as an alternative to organic has grown over the past decades. In this work, for first time, effect of dilution with water on physicochemical and antimicrobial properties lactic acid-based NADES choline chloride (NADES1), sorbitol (NADES2), glucose (NADES3) was systematically studied. According FTIR data, after NADESs water, strong hydrogen bonds weakened, however, were not destroyed up 40% water. resulted a linear decrease density refractive index increase pH. equations prediction density, pH, function content calculated. viscosity decreased by half adding approximately 10% initial NADES2 NADES3 significantly different. However, 20% almost same. most pronounced surface tension (by 46.7%) found NADES1. activity following order: > NADES1 NADES2. caused gradual activity. showed lowest minimal inhibitory concentrations (MIC) (7.8, 3.9, 0.98 mg/mL) minimum bactericidal (MBC) (15.6, 7.8, 1.95 Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, respectively. 2–8 times addition all tested together low pH could explain effect. revealed regularity can be useful selection laboratory industrial scale.

Language: Английский

Citations

4
Analysis of the bioactive parts and components of Aralia elata (Miq.) Seem based on non‐targeted metabolomics and its hepatoprotective effects induced by cyclophosphamide DOI
Jun‐Qi Zhang, Shanshan Chen, Haiyang Yan

et al.

Journal of Food Science, Journal Year: 2025, Volume and Issue: 90(2)

Published: Feb. 1, 2025

Abstract In the present study, non‐targeted metabolomics was utilized to identify bioactive components in root, seed, and leaf of Aralia elata (Miq.) Seem ( A. ), a traditional Chinese specialty vegetable. The relative content indicated that saponins, flavonoids, phenolic acids were main components, whereas principal component analysis showed significant differences among three parts. ABTS, DPPH, ferric reducing antioxidant power, hydroxyl radical scavenging capacity assays conducted evaluate activities extracts from parts, root extract demonstrated highest potential. Correlation analyses revealed saponins possessed best capacity. Twelve identified total (tSAs) by liquid chromatography–high‐resolution mass spectrometry. protective effect tSAs on cyclophosphamide‐induced liver damage evaluated using BRL‐3A cells. significantly enhanced cellular levels, reduced levels aspartate aminotransferase alanine 38.81% 37.43%, respectively, evident hepatoprotective effects. Practical Application This research could help develop dietary supplements rich antioxidants roots also pave way for novel therapies diseases.

Language: Английский

Citations

0
Comparison of Analytical Methods Used for Standardization of Triterpenoid Saponins in Herbal Monographs Included in the Russian and Other Pharmacopeias DOI Open Access
Л. Н. Фролова, Е. Л. Ковалева, V. V. Shelestova

et al.

Phytochemical Analysis, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 19, 2025

ABSTRACT Introduction Harmonization of methodological approaches to the analysis herbal substances containing triterpenoid saponins, considered largest group phytochemicals, is essential for pharmaceutical industry worldwide. Objectives This review aimed perform a comparative requirements standardization substances, medicinal products (HMPs), and other materials saponins in pharmacopeial texts Russian Federation world's leading pharmacopeias. Materials Methods The covers data on quantitative qualitative as presented State Register Medicinal Products Russia monographs pharmacopeias: European Pharmacopeia, United States British Japanese national pharmacopeias Eurasian Economic Union (EEU) Member States. Results compares discusses analytical methods used Aesculus hippocastanum L. seeds, Aralia elata (Miq.) Seem roots, Glycyrrhiza spp. Orthosiphon aristatu s (Blume) Miq. leaves, Polemonium caeruleum rhizomes with roots. most common are (HP)TLC (U)HPLC. Pharmacopeia also includes titrimetry spectrophotometry. Conclusions appropriate selection biologically active compounds HMP still challenging. We believe that rational approach HMPs should be based use maximum extractability specific pharmacological activity. harmonized procedures reference identification assay metabolites must implemented at all stages production control from finished dosage forms.

Language: Английский

Citations

0
Insight into the mechanism of efficient extraction of tea saponins from Camellia oleifera shells using deep eutectic solvents DOI

Xiangyan Mo,

Fangxue Hang,

Er-Fang Ren

et al.

Innovative Food Science & Emerging Technologies, Journal Year: 2025, Volume and Issue: unknown, P. 104001 - 104001

Published: March 1, 2025

Language: Английский

Citations

0
Influence of ultrasound extraction of Fucus vesiculosus on the kinetics of fucoidan degradation and its properties DOI Creative Commons
Ekaterina D. Obluchinskaya, Olga N. Pozharitskaya

Drug development & registration, Journal Year: 2025, Volume and Issue: unknown

Published: March 28, 2025

Introduction. A promising source for isolating fucoidan is Fucus vesiculosus L., a widespread species of brown algae. In recent years, the possibility using in medicine and pharmacy has been widely studied. The method extracting polysaccharides significantly affects their characteristics properties. To improve extraction efficiency, ultrasonic-assisted (UAE) recently explored. Aim. Study influence time low-frequency UAE algae F. on kinetics degradation its Materials methods. Fresh frozen L. were used as raw material. was carried out at an oscillation frequency 22 kHz temperature 25 °C. extract obtained 60 °C dynamic maceration method. homogeneity molecular weight analyzed by high-performance size exclusion chromatography (HPSEC). FT-IR spectra VERTEX 70 spectrometer. Quantitative determination fucose sulfates performed spectrophotometric antioxidant activity (AOA) assessed FRAP test. Mathematical statistical processing results accordance with Russian Federation Pharmacopeia XV edition MO Excel 2007 software. Results discussion. calculated rate 19.5 %/h. reaction constant half-life second-order model (R 2 > 0.97) 5.8 · 10 –6 mol/(g min) 110 min. Ultrasonic occurred predominantly due to random scission 0,98). Using FTIR spectrometry, it found that preliminary structures without ultrasound after not changed. Analysis showed ultrasonic extraction, despite decrease weight, demonstrated significant vitro. Conclusion. For first time, change conformational properties caused shown. leads average destruction sulfate groups. Overall, this study shows low which gentle, environmentally friendly can be completed short period, effectively critically changing activity.

Language: Английский

Citations

0
DEVELOPMENT OF A SUSTAINABLE EXTRACTION AND STORAGE STABILITY OF ANTIOXIDANT AND ANTICHOLINERGIC PRESSURIZED NATURAL DEEP EUTECTIC SOLVENT EXTRACTS FROM CITRUS RETICULATA LEAVES DOI Creative Commons
Gloria Domínguez‐Rodríguez, Víctor M. Amador-Luna, J. A. Mendiola

et al.

Food and Bioproducts Processing, Journal Year: 2024, Volume and Issue: 149, P. 70 - 81

Published: Nov. 8, 2024

Language: Английский

Citations

3
An integrative metabolomics and metagenomics analysis of functional microbiota examines the extraction of bioactive products using longan pericarp DOI
Yizhuo Zhang, Jun Huang, Rongqing Zhou

et al.

Biochemical Engineering Journal, Journal Year: 2024, Volume and Issue: 211, P. 109464 - 109464

Published: Aug. 11, 2024

Language: Английский

Citations

1
Naturally‐occurring nematicides of plant origin: two decades of novel chemistries DOI Creative Commons
H. Ibrahim, Vaderament‐A. Nchiozem‐Ngnitedem, Louise‐Marie Dandurand

et al.

Pest Management Science, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 6, 2024

Abstract Plant‐parasitic nematodes are among the most destructive plant pathogens, resulting in a global annual economic loss of about 358 billion dollars. Using synthetic nematicides to control plant‐parasitic has resulted broad‐spectrum toxicity environment. Plant‐derived secondary metabolites have recently emerged as viable options that provide effective, greener, and renewable routes for managing various cropping systems. However, limited comprehensive information on plant‐derived sources, chemical structures, nematicidal activities is available. This study aims compile analyze data plant‐based with properties collected over last two decades. In this review, we identified 262 were isolated from 35 families 65 species. Alkaloids, terpenoids, saponins, flavonoids, coumarins, thiophenes, annonaceous acetogenins studied compounds. addition structure–activity relation specific potency, techniques their extraction isolation material discussed. Our findings demonstrate potential plants feedstock sourcing compounds discovering new chemistries could potentially be used developing next generation nematicides. © 2024 The Author(s). Pest Management Science published by John Wiley & Sons Ltd behalf Society Chemical Industry.

Language: Английский

Citations

1