Abstract
The
iron
(ІІІ)‐promoted
tandem
cyclization
of
1‐(2‐(allyloxy)aryl)‐1
H
‐indoles
with
diselenides
has
been
developed
for
the
preparation
seleno‐benzo[2,3][1,4]oxazepino[4,5‐a]indole
derivatives.
investigation
to
determine
best
reaction
conditions
indicated
use
(0.2
mmol)
(1.5
equiv.)
and
iron(III)
chloride
in
acetonitrile
at
room
temperature
under
air,
more
than
48
examples
were
obtained.
features
access
selenized
7‐membered
containing
nitrogen‐oxygen
heterocyclic
skeleton,
which
also
represents
a
7‐exo‐trig
process
1‐(2‐((2‐methylallyl)oxy)aryl)‐1
diselenides.
Green Chemistry,
Journal Year:
2021,
Volume and Issue:
23(13), P. 4647 - 4655
Published: Jan. 1, 2021
Organoselenium-catalyzed
reactions
of
carbonyl
derivatives
can
produce
may
useful
compounds
under
mild
and
green
conditions.
This
article
aims
to
summarize
the
recent
advances
give
a
perspective
from
both
chemistry
safety
viewpoint.
Chemistry - A European Journal,
Journal Year:
2023,
Volume and Issue:
29(49)
Published: June 20, 2023
Benzamide-derived
organochalcogens
(chalcogen=S,
Se,
and
Te)
have
shown
promising
interest
in
biological
synthetic
chemistry.
Ebselen
molecule
derived
from
benzamide
moiety
is
the
most
studied
organoselenium.
However,
its
heavier
congener
organotellurium
under-explored.
Here,
an
efficient
copper-catalyzed
atom
economical
method
has
been
developed
to
synthesize
2-phenyl-benzamide
tellurenyl
iodides
by
inserting
a
tellurium
into
carbon-iodine
bond
of
2-iodobenzamides
one
pot
with
78-95
%
yields.
Further,
Lewis
acidic
nature
Te
center
basic
nitrogen
synthesized
2-Iodo-N-(quinolin-8-yl)benzamide
enabled
them
as
pre-catalyst
for
activation
epoxide
CO2
at
1
atm
preparation
cyclic
carbonates
TOF
TON
values
1447
h-1
4343,
respectively,
under
solvent-free
conditions.
In
addition,
2-iodo-N-(quinolin-8-yl)benzamide
also
used
activating
anilines
form
variety
1,3-diaryl
ureas
up
95
yield.
The
mechanistic
investigation
mitigation
done
125
NMR
HRMS
studies.
It
seems
that
reaction
proceeds
via
formation
catalytically
active
Te-N
heterocycle,
ebtellur
intermediate
which
isolated
structurally
characterized.
The Journal of Organic Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 24, 2025
Herein,
an
atom
efficient
and
one-pot
protocol,
offering
a
series
of
sulfonylated
pyrrolo[2,3-b]quinolines
via
C-N,
C-C,
C-S
bond
formation,
has
been
developed
with
inexpensive
copper
catalyst.
Notably,
the
reaction
proceeds
double-annulation
followed
by
1,3-sulfonyl
migration
sequence.
Moreover,
method
is
applicable
to
broad
range
2-carbonylanilines.
Furthermore,
synthetic
applications
scale-up
highlight
utility
potential
this
protocol.
In
addition,
antimalarial
property
showed
parasite
inhibition
without
cytotoxic
effects
in
mammalian
cells.
Green Chemistry,
Journal Year:
2021,
Volume and Issue:
23(19), P. 7544 - 7548
Published: Jan. 1, 2021
A
sustainable,
highly
chemoselective,
regioselective
and
cis
-selective
radical
isothiocyano-chalcogenization
of
alkenes
with
NH
4
SCN
in
water
is
disclosed.
Chemical Communications,
Journal Year:
2022,
Volume and Issue:
58(50), P. 7050 - 7053
Published: Jan. 1, 2022
A
one
pot
Cu(I)-assisted
synthetic
methodology
has
been
developed
for
the
preparation
of
biologically
important
C2-symmetric
spirodiaza,
benzyloxy
and
benzoxytelluranes
from
2-bromo-N-aryl
benzamides,
benzyl
alcohols,
benzoic
acids
by
using
tellurium
dianion
(Te2-)
under
base-free
conditions.
Furthermore,
C-C
coupled
biaryl
1,1'-diamides
have
prepared
an
excess
Na2Te
same
reaction
The
synthesized
spirodiazatelluranes
served
as
a
potent
catalyst
reduction
H2O2
nitro-Michael
reactions.
Industrial & Engineering Chemistry Research,
Journal Year:
2021,
Volume and Issue:
60(24), P. 8659 - 8663
Published: June 10, 2021
In
this
work,
the
end-capping
strategy
was
adopted
in
selenized
material
production
for
first
time.
Methylselenized
glucose,
as
a
new-generation
glucose
product,
designed
and
synthesized
under
NaBH4-free
conditions,
avoiding
generation
of
hydrogen
gas.
comparison
with
reported
works,
new
method
significantly
reduced
cost
enhanced
safety.
The
produced
methylselenized
an
even
more
stable
low-valent
Se
it
hardly
oxidized
by
air,
resulting
elevated
efficiency
serving
practical
fertilizer
Se-enriched
crop
planting.
Abstract
Electrosynthesis
of
selenylated‐oxazolone
derivatives
via
cascade
selenylation/cyclization
ynamides
was
disclosed.
A
series
diaryl
diselenides,
dialkyl
and
heteroaryl‐substituted
tolerated
in
this
protocol
delivered
4‐selenyloxazolones
28–83%
yields.
The
scale‐up
reaction
the
oxidation
performed
to
showcase
practicability
method.
Furthermore,
mechanistic
experiments
indicated
that
a
cationic
pathway
instead
radical
probably
involved.
