Chemistry & Biodiversity,
Journal Year:
2023,
Volume and Issue:
20(8)
Published: July 7, 2023
Abstract
An
efficient
metal‐free
approach
for
site
selective
C−N
coupling
reaction
of
benzo[d]isoxazole
and
2
H
‐chromene
derivatives
has
been
designed
developed
against
AchE.
This
nitrogen
containing
organo‐base
promoted
methodology,
which
is
both
practical
environmentally
friendly,
provides
an
easy
suitable
pathway
synthesizing
Benzisoxazole‐Chromene
(BC)
possessing
poly
heteroaryl
moieties.
The
synthesized
BC
4
a
–
n
was
docked
into
the
active
sites
AChE
to
obtain
more
perception
binding
modes
compounds.
Out
them,
compound
l
displayed
potent
activity
high
selectivity
inhibition.
Final
docking
results
indicates
that
showed
lowest
energy
−11.2260
kcal/mol
with
AChE.
analogs
would
be
potential
candidates
promoting
studies
in
medicinal
chemistry
research.
Organic & Biomolecular Chemistry,
Journal Year:
2022,
Volume and Issue:
20(34), P. 6766 - 6770
Published: Jan. 1, 2022
Triflic
acid
promoted
multicomponent
synthesis
of
functionalized
S
-benzyl
dithiocarbamates
from
diazo
compounds
and
secondary
amines
in
the
presence
carbon
disulfide
is
described.
Organic & Biomolecular Chemistry,
Journal Year:
2023,
Volume and Issue:
21(31), P. 6360 - 6367
Published: Jan. 1, 2023
S
-Alkylation
of
dithiocarbamates
using
alcohols
as
alkylating
agents
via
a
hydrogen
borrowing
strategy
hydroxyapatite-supported
copper
nanoparticles
heterogeneous
catalyst.
Asian Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
13(5)
Published: March 7, 2024
Abstract
Herein
we
report,
the
synthesis
of
single‐atom
iron
on
nitrogen‐doped
carbon
as
a
catalyst
for
direct
formation
C
sp3
−S
bond
via
borrowing
hydrogen
strategy
using
alcohols
alkylating
agent.
The
was
synthesized
by
encapsulating
ferrocene
within
ZIF‐8
framework,
followed
pyrolysis
and
characterized
precisely
FE‐SEM,
HR‐TEM,
XPS,
Raman,
XRD
EXAFS.
is
robust,
displayed
an
excellent
reactivity
in
reaction
could
be
recycled
five
times
without
any
appreciable
loss
activity.
Jurnal Kimia Sains dan Aplikasi,
Journal Year:
2024,
Volume and Issue:
27(7), P. 300 - 306
Published: May 28, 2024
The
complex
compound
dithiocarbamate
exhibits
various
biological
activities,
including
anticancer,
antibacterial,
antifungal,
and
antioxidant
properties.
Dibutyl
tin
(IV)
N-ethyl
benzyl
was
synthesized
to
overview
its
structure
evaluate
antibacterial
activity
against
Salmonella
typhimurium
ATCC
14028
Propionibacterium
acnes.
This
via
an
in
situ
method
by
adding
dibutyl
dichloride,
N-ethylbenzylamine,
carbon
disulfide,
forming
a
precipitate,
which
then
dried
yield
white
powder.
powder
can
also
be
crystallized.
characterized
using
FTIR,
1H
NMR,
13C
NMR
spectroscopy,
along
with
testing
the
disc
diffusion
method.
FTIR
analysis
revealed
characteristic
absorption
bands
at
1111.00
cm-1
(C-N),
731.02
(C-S),
2954.95
(C-H),
1602.85
(C=C),
360.69
(Sn-S),
567.07
(Sn-C).
spectrum
showed
chemical
shifts
0-3.8570
ppm
(δ
CH3),
5.0032-5.1472
N-CH2),
7.2780-7.3607
C6H5).
displayed
signals
0-34.5610
48.6398-56.9247
127.6651-135.7665
C6H5),
201.7568
CS2).
of
assessed,
revealing
inhibition
zones
typhi
6.78
mm
(100
ppm),
7.36
(120
7.76
(140
categorizing
as
moderate.
Against
acnes,
were
1.8
1.88
2.13
weak.
Based
on
these
findings,
it
concluded
that
form
octahedral
activity.
However,
is
not
yet
suitable
for
use
new
antibiotic.
Proceedings of universities Applied chemistry and biotechnology,
Journal Year:
2023,
Volume and Issue:
13(2), P. 160 - 171
Published: July 1, 2023
Ore
flotation
is
the
main
and
defining
technological
process
in
ore
benefication
non-ferrous
metals
production.
The
requires
use
of
a
variety
chemical
reagents,
including
collectors,
frothers,
surface
modifiers,
pH
regulators.
development
selection
suitable
reagents
for
processed
material
play
vital
role
efficient
flotation.
activity
collectors
depends
fundamentally
on
composition
structure
hydrophobic
hydrophilic
fragments
forming
agent
molecule,
as
well
nature
that
undergoes
processing.
In
this
regard,
identification
study
“substance
structure–flotation
activity”
relation,
search
new
effective
gain
importance
within
applied
organic
organoelement
chemistry
related
branches
science
technology.
article,
we
review
syntheses
collector
namely
xanthates
dithiocarbamates,
based
literature
data
past
five
years.
Where
necessary,
earlier
sources
are
provided.
reaction
conditions
yields
target
compounds
presented
using
schemes.
addition,
present
results
tests
surfaces
various
ores
mechanism
concentrate
extraction.
According
to
reviewed
publications,
fixation
minerals
can
be
regarded
complexation
functional
groups
metal
ions
located
mineral.
Organic & Biomolecular Chemistry,
Journal Year:
2023,
Volume and Issue:
21(31), P. 6293 - 6297
Published: Jan. 1, 2023
An
efficient
method
for
the
preparation
of
six-membered
cyclic
dithiocarbamates
is
described,
in
which
triethylamine
effectively
promotes
reaction
1-amino-3-chloropropan-2-ol
derivatives
with
carbon
disulfide.
On
basis
experimental
and
theoretical
studies,
a
mechanism
proposed
to
explain
difference
between
present
our
previously
reported
dioxide
fixation.
Asian Journal of Organic Chemistry,
Journal Year:
2022,
Volume and Issue:
11(8)
Published: July 2, 2022
Abstract
A
facile
and
efficient
method
for
the
synthesis
of
α
‐diarylmethyl
substituted
phenols
from
para
‐quinone
methides
(
p
‐QMs)
with
has
been
developed
by
using
phosphoric
acid
as
catalyst
water
green
solvent
under
mild
conditions.
In
addition,
when
TEMPO
was
added
an
additive
reaction,
diaryl‐substituted
could
be
generated
target
product.
The
reactions
show
high
functional
group
tolerance,
good
to
excellent
yields
unique
selectivity,
a
broad
range
motif
containing
phenol(s)
quinones
prepared
through
divergent
methods.
Furthermore,
series
control
experiments
were
performed
gain
insights
plausible
mechanisms.
These
protocols
have
atomic
economy,
may
significant
implications
construction
C(
sp
3
)−C(
2
)
bonds
in
organic
synthesis.
