Synthesis of 4-Hydroxy-5-phenylaminoimidazoles through a Three-Component Reaction of Sulfur Ylides, Nitrosobenzenes, and Amidines DOI

Chaowei Xiang,

Gongruixue Zeng,

Yi Hao

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(24), P. 18227 - 18234

Published: Nov. 27, 2024

A novel annulation reaction of amidines with sulfur ylides and nitrobenzenes has been developed, affording various 4-hydroxy-5-phenylaminoimidazoles in moderate to excellent yields. The have further converted into α-ketoamide imidazol-4-imine derivatives. Moreover, a plausible mechanism for this multicomponent is proposed.

Language: Английский

Direct Synthesis of α-Ketothioamide Derivatives through a One-Pot Reaction of Sulfur Ylides, Nitrosobenzenes, and Thioacetic Acid DOI

Chaowei Xiang,

Fang Luo, Zheng Wang

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(12), P. 8878 - 8887

Published: June 7, 2024

A one-pot approach has been developed for the synthesis of α-ketothioamide derivatives from sulfur ylides, nitrosobenzenes, and thioacetic acid. This protocol is carried out under mild reaction conditions in generally moderate to excellent yields without any precious catalysts, affording with structural diversity. Additionally, a possible mechanism this chemical transformation proposed.

Language: Английский

Citations

3
Au(PPh3)Cl/AgOTf/TsOH-Catalyzed Cascade Reaction between 1-(2-Hydroxyphenyl)-propargyl Alcohols and β-Oxoketones (Amides, Acid): Diastereoselective Construction of cis-3a,8a-Dihydrofuro[2,3-b]benzofuran Framework DOI

Yangyi Zhang,

Guisheng Deng

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 20, 2024

In the Au(PPh

Language: Английский

Citations

2
The Synthesis of Benzazepines via Sequential [3 + 2]-Annulation and [3,3]-Sigmatropic Rearrangement DOI
Fang Luo, Wei Wang,

Chaowei Xiang

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(48), P. 10224 - 10228

Published: Nov. 22, 2024

A novel annulation reaction of prop-2-ynylsulfonium salts with sulfur ylides and nitrosobenzenes has been developed, affording various benzazepines in moderate to good yields. Prop-2-ynylsulfonium act as C

Language: Английский

Citations

1
Synthesis of 4-Hydroxy-5-phenylaminoimidazoles through a Three-Component Reaction of Sulfur Ylides, Nitrosobenzenes, and Amidines DOI

Chaowei Xiang,

Gongruixue Zeng,

Yi Hao

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(24), P. 18227 - 18234

Published: Nov. 27, 2024

A novel annulation reaction of amidines with sulfur ylides and nitrobenzenes has been developed, affording various 4-hydroxy-5-phenylaminoimidazoles in moderate to excellent yields. The have further converted into α-ketoamide imidazol-4-imine derivatives. Moreover, a plausible mechanism for this multicomponent is proposed.

Language: Английский

Citations

0