Intramolecular Silanoxy-Michael Reactions with Pendant Nitroalkenes: Racemic and Enantioselective DOI
Harshit Joshi, Shyam Sathyamoorthi

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 21, 2024

We present the first racemic and scalemic examples of di-

Language: Английский

Synthesis of alduronic acid lactones and rare sugar glyconolactones via decarboxylative oxygenation of uronic acids: construction of polyhydroxylated fused-ring alkaloids DOI
Pengwei Chen,

Ma Xian,

Song Ni

et al.

Chinese Chemical Letters, Journal Year: 2025, Volume and Issue: unknown, P. 110983 - 110983

Published: Feb. 1, 2025

Language: Английский

Citations

1
Recent Advancement on Selectfluor Mediated Synthesis of Heterocyclic Molecules DOI Open Access
Sukanya Das, Rudra Narayan Das, Tapas Ghosh

et al.

The Chemical Record, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 16, 2025

Abstract Selectfluor, [1‐chloromethyl‐4‐fluoro‐1,4‐diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate)], is a highly valuable reagent in contemporary chemistry, serving not only as an electrophilic fluorinating agent but also effective catalyst the synthesis of various pharmaceutically relevant heterocycles. This review article seeks to present comprehensive overview significant heterocyclic ring formations facilitated by selectfluor. Both metal‐free and metal‐catalyzed recent advancement on selectfluor mediated cyclisation processes are discussed this mainly over last eight years (2017‐April 2024).

Language: Английский

Citations

1
Iron‐Based Deep Eutectic Solvents: Key Players for Amide and Sulfonamide Synthesis and Alcohol Oxidation DOI
Luciana Cicco,

Sara Urselli,

Claudia Favia

et al.

European Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 27(24)

Published: April 22, 2024

Abstract A sustainable protocol has been devised for the oxidation of activated secondary alcohols to their corresponding carbonyl compounds, as well utilization selective mono‐alkylating reagents both amide and arylsulfonamide derivatives. These reactions proceed smoothly in good yields (up 98 %) when conducted Fe‐based deep eutectic solvents (DESs), which serve dual roles catalysts. Operating under mild (40 °C) aerobic conditions, these transformations are completed within a 4 h time frame. pharmacologically relevant derivative, specifically PMRT1 inhibitor, also successfully synthesized on 3 g‐scale utilizing reusable FeCl ⋅ 6H 2 O/glycerol Lewis acidic DES.

Language: Английский

Citations

3
Harnessing tethered nitreniums for diastereoselective amino-sulfonoxylation of alkenes DOI Creative Commons
Shyam Sathyamoorthi,

Appasaheb K. Nirpal,

Dnyaneshwar A. Gorve

et al.

Beilstein Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: 21, P. 947 - 954

Published: May 19, 2025

We present the first examples of alkene amino-sulfonoxylation reactions that leverage unique reactivity carbamate tethered N -alkoxy nitrenium ions. In almost all cases examined, deliver product with exquisite regioselectivity and diastereoselectivity. The protocols followed are operationally very simple only use commercial I(III) reagents sulfonic acids, amounting to a metal-free protocol for amino-oxygenation. No special precautions need be taken exclude air or ambient moisture, products amenable further transformations.

Language: Английский

Citations

0
Carboxylic Acids DOI

Rupali Dasharath Shinde,

Shivani Singh Chauhan,

Harikrushn G Kakadiya

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Citations

0
Recent advances in the synthesis of 3,3-disubstituted oxetanes DOI
Hikaru Ishikura, James A. Bull

Advances in heterocyclic chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 159 - 209

Published: Jan. 1, 2024

Language: Английский

Citations

1
Intramolecular Silanoxy-Michael Reactions with Pendant Nitroalkenes, Racemic and Enantioselective DOI Creative Commons
Shyam Sathyamoorthi, Harshit Joshi

Published: June 4, 2024

We present the first racemic and scalemic examples of di-tert-butyl silanoxy Michael additions. Our operationally simple protocol is selective for nitro-olefins simply involves stirring substrate with an appropriate hydrogen-bond donor catalyst without any special precautions to exclude air or moisture. For each examined, we have developed complementary protocols which respectively optimize yield enantioselectivity. reactions scale well, products are valuable intermediates further transformations, including preparation enantioenriched vicinal amino-alcohols.

Language: Английский

Citations

1
The oxidation of 2-phenyl ethanols by Fe(NO3)3·9H2O in CF3COOH: the dramatic substituent effect DOI

Zhe Jia,

Pu Zhang, Zhi‐Xin Guo

et al.

Journal of Organometallic Chemistry, Journal Year: 2024, Volume and Issue: 1018, P. 123288 - 123288

Published: July 31, 2024

Language: Английский

Citations

1
New Features of the H2SO4–HNO3 System in the Synthesis of Adamantanecarboxylic Acids DOI
Elena I. Ivleva,

D. V. Zvereva,

Yu. N. Klimochkin

et al.

Russian Journal of General Chemistry, Journal Year: 2024, Volume and Issue: 94(8), P. 1905 - 1911

Published: Aug. 1, 2024

Language: Английский

Citations

1
The Oxidation of 2-Phenyl Ethanols by Fe(No3)3.9h2o in Cf3cooh: The Dramatic Substituent Effect DOI
Zhi‐Xin Guo, Pu Zhang,

Zhe Jia

et al.

Published: Jan. 1, 2024

Download This Paper Open PDF in Browser Add to My Library Share: Permalink Using these links will ensure access this page indefinitely Copy URL DOI

Language: Английский

Citations

0