Six-membered ring systems: With O and/or S atoms DOI
Clementina M.M. Santos, Artur M. S. Silva

Progress in heterocyclic chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 421 - 484

Published: Jan. 1, 2024

Language: Английский

Transition metal-free tunable synthesis of 3-(trifluoromethylthio) and 3-trifluoromethylsulfinyl chromones via domino C-H functionalization and chromone annulation of enaminones DOI
Tao Zhou, Jing Zhou, Yunyun Liu

et al.

Chinese Chemical Letters, Journal Year: 2024, Volume and Issue: 35(11), P. 109683 - 109683

Published: March 2, 2024

Language: Английский

Citations

15
Recent progress in visible light‐driven halogenation: Chlorination, bromination, and iodination DOI

Anh Thu Nguyen,

Houng Kang, Truong Giang Luu

et al.

Bulletin of the Korean Chemical Society, Journal Year: 2024, Volume and Issue: 45(9), P. 738 - 758

Published: Sept. 1, 2024

Abstract Halogenation is one of the most important transformations in organic synthesis. Halogenated compounds are employed many reactions to prepare useful molecules. Many methods have been developed introduce halogens into different compounds. Visible light‐mediated efficient, low‐toxic, and mild‐condition applied for various chemistry transformations. Remarkably, there has an increasing development application visible light‐induced halogenation recent years. Herein, we present a comprehensive summary including chlorination, bromination, iodination under light irradiation since 2020.

Language: Английский

Citations

5
Platform of Oxidative Transformation of α-Methyl Secondary Enaminones toward Tetrahydropyridines DOI
Fei Huang, Mingrui Li, Quanbin Jiang

et al.

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 20, 2025

In this paper, the application of α-methyl secondary enaminones in synthesis tetrahydrofuropyridines is described. The key step methodology situ generation 1-azadiene from oxidation enaminone, followed by a subsequent inverse-electron-demand hetero-Diels–Alder reaction proceeded to give desired product. Mechanistic studies and density functional theory (DFT) calculations revealed detailed pathway. Gram-scale preparation experiments further transformation product demonstrate potential applicability method. addition, amide derivatives could be obtained employing β-methyl as substrates under similar oxidative conditions. present work opens new window rarely reported enaminones.

Language: Английский

Citations

0
An update on the advances in chromone and the derivatives synthesis based on the key chromone annulation of o-hydroxyaryl enaminones DOI
Liu‐Liang Mao, Yunyun Liu, Jie‐Ping Wan

et al.

Chinese Chemical Letters, Journal Year: 2024, Volume and Issue: unknown, P. 110784 - 110784

Published: Dec. 1, 2024

Language: Английский

Citations

3
Synthesis of 2,4-Dicyanoalkylated Benzoxazines through the Radical-Mediated Cascade Cyclization of Isocyanides with AIBN under Metal- and Additive-Free Conditions DOI

Mengjia Ni,

Shuanggen Gui,

Yang Fu

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(6), P. 3970 - 3976

Published: Feb. 29, 2024

A general and novel method for the radical cascade cyclization of aryl isocyanides with AIBN has been described. This strategy provides straightforward access to various 2,4-dicyanoalkylated benzoxazines in moderate good yields under metal- additive-free conditions. The reaction can apply a gram scale tolerate diverse functional groups. 2,4-Dicyanoalkylated benzoxazine derivatives feature large Stokes shift intramolecular charge transfer properties.

Language: Английский

Citations

1
Visible Light Mediated Synthesis of 3‐Indolmethyl Chromones via the Cyclization of o‐Hydroxyaryl Enaminones with 3‐Indoleacetic Acids Catalyzed by Graphitic Carbon Nitride Adorned with Copper Nanoparticles DOI

Nandish Talpada,

Anuj S. Sharma, Vinay S. Sharma

et al.

ChemNanoMat, Journal Year: 2024, Volume and Issue: 10(5)

Published: March 18, 2024

Abstract Copper nanoparticles ( Cu 2 O NPs ) supported on graphitic carbon nitride g‐C 3 N 4 have been introduced as an effective heterogenous catalyst for the synthesis of 3‐indolmethyl chromones a–q under visible light conditions via cyclization o ‐hydroxyaryl enaminones with 3‐indoleacetic acids. The was thoroughly characterized using various techniques such FT‐IR, PXRD, XPS, FE‐SEM, EDX, TEM, and HR‐TEM analysis. optimized reaction enabled high yield production a wide range in short timespan at room temperature method successfully applied to gram‐scale synthesis. Importantly, could be reused up five cycles without significant decrease its activity. This approach aligns eco‐friendly principles, demonstrating favorable green chemistry metrics compound , including process mass intensity (7.83), environmental impact factor (6.83), atom economy (67.56 %), efficiency (60.76 chemical (92.37 (1.64), productivity (60.97 (69.15 %) optimum (89.93 %).

Language: Английский

Citations

1
Synthesis of 3-Substituted Chromones through Photoactivation of Acceptor–Acceptor Diazo Compounds DOI
Namrata Rastogi, Prashant Kumar, Asit Kumar

et al.

Synthesis, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 4, 2024

Abstract We report the photocatalytic alkylation of o-hydroxyarylenaminones with acceptor–acceptor diazo compounds to access 3-alkyl chromones. The reaction involves triplet sensitization substrate via energy transfer from photosensitizer. notable features protocol are operational simplicity, wide scope, and generally high yields products.

Language: Английский

Citations

0
Six-membered ring systems: With O and/or S atoms DOI
Clementina M.M. Santos, Artur M. S. Silva

Progress in heterocyclic chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 421 - 484

Published: Jan. 1, 2024

Language: Английский

Citations

0