Cascade Cyclization of N-Cyanamide Alkenes for the Divergent Synthesis of Azido-, Nitro-, and Alkenyl-Containing Pyrroloquinazolinones
Bo Jiang,
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Cui Zhang,
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Tai‐Gang Fan
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et al.
Organic Letters,
Journal Year:
2024,
Volume and Issue:
26(38), P. 8028 - 8033
Published: Sept. 16, 2024
Radical
cascade
cyclizations
of
Thiolative Annulation of N-Benzyl-N-cyanopropiolamides Leading to Divergent Synthesis of Pyrroloquinazolin-1-ones and Maleimides
Chada Raji Reddy,
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Anootha Neeliveettil,
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Uprety Ajaykumar
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et al.
Organic Letters,
Journal Year:
2025,
Volume and Issue:
unknown
Published: May 8, 2025
An
unprecedented
successive
radical-promoted
thiolative
annulation/Pd-catalyzed
C-H
amination
of
N-benzyl-N-cyanopropiolamides
to
access
pyrrolo[2,1-b]quinazolin-1(9H)-ones
in
a
one-pot
manner
is
described.
Moreover,
altering
the
step
with
oxidation
(reagent
switch)
offered
maleimides
from
same
set
readily
accessible
precursors.
Both
transformations
display
versatility
across
wide
range
substrates,
enabling
efficient
various
functionalized
quinazolin-1-ones
and
good
yields.
Language: Английский
Entry to 4,5-Fused Coumarin frameworks via Radical-Promoted Alkylative Intramolecular C5-Annulation
Chada Raji Reddy,
No information about this author
Venkatareddy Edhara,
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Ankita Kumari
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et al.
Organic & Biomolecular Chemistry,
Journal Year:
2024,
Volume and Issue:
22(31), P. 6385 - 6392
Published: Jan. 1, 2024
A
silver-catalyzed
oxidative
protocol
for
the
synthesis
of
previously
unfamiliar
4,5-fused
coumarins
is
disclosed.
Language: Английский
Visible‐Light Enabled Synthesis of 1‐Aryl‐3‐Sulfonylmethyl‐1,2,4‐Triazoles by Arylazo Sulfones
Advanced Synthesis & Catalysis,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 5, 2024
Abstract
We
present
a
novel
and
highly
efficient
method
for
synthesizing
polyfunctionalized
1,2,4‐triazoles.
This
approach
leverages
visible
light
arylazo
sulfones
in
combination
with
N
‐vinyl
amides,
the
environmentally
friendly
solvent
ethyl
acetate.
Remarkably,
reaction
proceeds
without
need
(photo)catalysts,
ensuring
near‐perfect
atom
economy
producing
only
water
as
by‐product.
exhibits
excellent
functional
group
tolerance
can
be
scaled
both
batch
continuous‐flow
processes.
Language: Английский