Visible‐Light Enabled Synthesis of 1‐Aryl‐3‐Sulfonylmethyl‐1,2,4‐Triazoles by Arylazo Sulfones DOI Creative Commons
Luca Nicchio, Lorenzo Di Terlizzi, Maurizio Fagnoni

et al.

Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 5, 2024

Abstract We present a novel and highly efficient method for synthesizing polyfunctionalized 1,2,4‐triazoles. This approach leverages visible light arylazo sulfones in combination with N ‐vinyl amides, the environmentally friendly solvent ethyl acetate. Remarkably, reaction proceeds without need (photo)catalysts, ensuring near‐perfect atom economy producing only water as by‐product. exhibits excellent functional group tolerance can be scaled both batch continuous‐flow processes.

Language: Английский

Thiolative Annulation of N-Benzyl-N-cyanopropiolamides Leading to Divergent Synthesis of Pyrroloquinazolin-1-ones and Maleimides DOI
Chada Raji Reddy,

Anootha Neeliveettil,

Uprety Ajaykumar

et al.

Organic Letters, Journal Year: 2025, Volume and Issue: unknown

Published: May 8, 2025

An unprecedented successive radical-promoted thiolative annulation/Pd-catalyzed C-H amination of N-benzyl-N-cyanopropiolamides to access pyrrolo[2,1-b]quinazolin-1(9H)-ones in a one-pot manner is described. Moreover, altering the step with oxidation (reagent switch) offered maleimides from same set readily accessible precursors. Both transformations display versatility across wide range substrates, enabling efficient various functionalized quinazolin-1-ones and good yields.

Language: Английский

Citations

0
Cascade Cyclization of N-Cyanamide Alkenes for the Divergent Synthesis of Azido-, Nitro-, and Alkenyl-Containing Pyrroloquinazolinones DOI
Bo Jiang, Cui Zhang,

Tai‐Gang Fan

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(38), P. 8028 - 8033

Published: Sept. 16, 2024

Radical cascade cyclizations of

Citations

3
Entry to 4,5-Fused Coumarin frameworks via Radical-Promoted Alkylative Intramolecular C5-Annulation DOI
Chada Raji Reddy,

Venkatareddy Edhara,

Ankita Kumari

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: 22(31), P. 6385 - 6392

Published: Jan. 1, 2024

A silver-catalyzed oxidative protocol for the synthesis of previously unfamiliar 4,5-fused coumarins is disclosed.

Language: Английский

Citations

1
Visible‐Light Enabled Synthesis of 1‐Aryl‐3‐Sulfonylmethyl‐1,2,4‐Triazoles by Arylazo Sulfones DOI Creative Commons
Luca Nicchio, Lorenzo Di Terlizzi, Maurizio Fagnoni

et al.

Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 5, 2024

Abstract We present a novel and highly efficient method for synthesizing polyfunctionalized 1,2,4‐triazoles. This approach leverages visible light arylazo sulfones in combination with N ‐vinyl amides, the environmentally friendly solvent ethyl acetate. Remarkably, reaction proceeds without need (photo)catalysts, ensuring near‐perfect atom economy producing only water as by‐product. exhibits excellent functional group tolerance can be scaled both batch continuous‐flow processes.

Language: Английский

Citations

0