Droplet-Based Microfluidics: Applications in Pharmaceuticals
Pharmaceuticals,
Journal Year:
2023,
Volume and Issue:
16(7), P. 937 - 937
Published: June 28, 2023
Droplet-based
microfluidics
offer
great
opportunities
for
applications
in
various
fields,
such
as
diagnostics,
food
sciences,
and
drug
discovery.
A
droplet
provides
an
isolated
environment
performing
a
single
reaction
within
microscale-volume
sample,
allowing
fast
with
high
sensitivity,
throughput,
low
risk
of
cross-contamination.
Owing
to
several
remarkable
features,
droplet-based
microfluidic
techniques
have
been
intensively
studied.
In
this
review,
we
discuss
the
impact
microfluidics,
particularly
focusing
on
screening
development.
addition,
surveyed
methods
device
fabrication
generation/manipulation.
We
further
highlight
some
promising
studies
covering
synthesis
delivery
that
were
updated
last
5
years.
This
review
researchers
quick
guide
includes
most
up-to-date
relevant
information
latest
scientific
findings
development
pharmaceutical
field.
Language: Английский
Novel caffeic acid grafted chitosan-sodium alginate microcapsules generated by microfluidic technique for the encapsulation of bioactive peptides from silkworm pupae
Xiao‐Meng Xun,
No information about this author
Zhi-Ang Zhang,
No information about this author
Zi-Xuan Yuan
No information about this author
et al.
Sustainable Chemistry and Pharmacy,
Journal Year:
2023,
Volume and Issue:
32, P. 100974 - 100974
Published: Feb. 2, 2023
Language: Английский
Synthesis of energetic materials by microfluidics
Defence Technology,
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 1, 2024
Energetic
materials,
characterized
by
their
capacity
to
store
and
release
substantial
energy,
hold
pivotal
significance
in
some
fields,
particularly
defense
applications.
Microfluidics,
with
its
ability
manipulate
fluids
facilitate
droplet
formation
at
the
microscale,
enables
precise
control
of
chemical
reactions.
Recent
scholarly
endeavors
have
increasingly
harnessed
microfluidic
reactors
realm
energetic
yielding
morphologically
controllable
particles
enhanced
uniformity
explosive
efficacy.
However,
crucial
insights
into
microfluidic-based
methodologies
are
dispersed
across
various
publications,
necessitating
a
systematic
compilation.
Accordingly,
this
review
addresses
gap
concentrating
on
synthesis
materials
through
microfluidics.
Specifically,
methods
based
micro-mixing
droplets
previous
papers
summarized
strategies
critical
parameters
within
reactions
discussed
detail.
Then,
comparison
terms
advantages
disadvantages
is
attempted.
As
demonstrated
last
section
regarding
perspectives,
challenges
such
as
clogging,
dead
zones,
suboptimal
production
yields
non-ignoble
promising
fields
they
might
be
addressed
integrating
sound,
optics,
or
electrical
energy
meet
heightened
requirements.
This
comprehensive
overview
aims
consolidate
analyze
diverse
array
approaches
material
synthesis,
offering
valuable
for
future
research
directions.
Language: Английский
Artificial intelligence-accelerated high-throughput screening of antibiotic combinations on a microfluidic combinatorial droplet system
Deyu Yang,
No information about this author
Ziming Yu,
No information about this author
Mengxin Zheng
No information about this author
et al.
Lab on a Chip,
Journal Year:
2023,
Volume and Issue:
23(18), P. 3961 - 3977
Published: Jan. 1, 2023
Microfluidic
platforms
have
been
employed
as
an
effective
tool
for
drug
screening
and
exhibit
the
advantages
of
lower
reagent
consumption,
higher
throughput
a
degree
automation.
Despite
great
advancement,
it
remains
challenging
to
screen
complex
antibiotic
combinations
in
simple,
high-throughput
systematic
manner.
Meanwhile,
large
amounts
datasets
generated
during
process
generally
outpace
abilities
conventional
manual
or
semi-automatic
data
analysis.
To
address
these
issues,
we
propose
artificial
intelligence-accelerated
combinatorial
evaluation
system
(AI-HTCDES),
which
not
only
allows
production
with
varying
concentrations,
but
can
also
automatically
analyze
dynamic
growth
bacteria
under
action
different
combinations.
Based
on
this
system,
several
displaying
additive
effect
are
discovered,
dosage
regimens
each
component
determined.
This
strategy
provides
useful
guidance
clinical
use
combination
therapy
personalized
medicine,
offers
promising
screenings
other
medicines.
Language: Английский
Analysis of SAW Temperature Properties in KTiOPO4 Single Crystal
Materials,
Journal Year:
2022,
Volume and Issue:
16(1), P. 69 - 69
Published: Dec. 21, 2022
The
surface
acoustic
wave
(SAW)
properties
of
potassium
titanyl
phosphate
(KTiOPO4,
KTP)
single
crystal
were
evaluated
by
numerical
methods.
phase
velocity,
electromechanical
coupling
coefficient,
power
flow
deflection
angle,
and
temperature
coefficient
delay
(TCD)
determined
for
different
cuts
KTP.
It
was
shown
that
SAW
has
the
0.59%
TCD
62
ppm/°C
on
Z-cut
propagation
direction
along
X
+
70°-axis.
For
X-axis,
pseudo-surface
(PSAW)
is
characterized
0.46%
value
57
ppm/°C.
Bleustein–Gulyaev
(BG)
35
41
Y-
X-cuts
KTP,
respectively.
Language: Английский