Chemistry of Heterocyclic Compounds, Journal Year: 2023, Volume and Issue: 59(4-5), P. 193 - 200
Published: May 1, 2023
Language: Английский
Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(20), P. 5813 - 5819
Published: Jan. 1, 2024
In this paper, we have developed an efficient strategy for the concise synthesis of diverse selenyl imidazo[2,1- b ]thiazinones via electrochemical oxidative three-component tandem reactions in absence transition metals, and oxidants.
Language: Английский
Citations
4
Chemistry - A European Journal, Journal Year: 2021, Volume and Issue: 27(60), P. 14931 - 14935
Published: Aug. 27, 2021
An electrochemical three component cascade phosphorylation reaction of various heteroatoms-containing nucleophiles including carbazoles, indoles, phenols, alcohols, and thiols with Ph2 PH has been established. Electricity is used as the "traceless" oxidant water air are utilized "green" oxygen source. All kinds structurally diverse organophosphorus compounds P(O)-N/P(O)-O/P(O)-S bonds assembled in moderate to excellent yields (three categories products, 50 examples, up 97 % yield). A tentative free radical course put forward rationalize procedure.
Language: Английский
Citations
24
Advanced Synthesis & Catalysis, Journal Year: 2022, Volume and Issue: 364(4), P. 909 - 913
Published: Jan. 11, 2022
Abstract A palladium‐catalyzed stereoselective intramolecular Heck dearomative of indoles with silyl termination has been developed. type tetracyclic indoline derivatives containing silicon were prepared, involving N ‐(2‐bromobenzoyl)indoles and silylboronates. This protocol not only led to a broad substrate scope in acceptable yields but also could be scaled up gram quantities as well further synthetic transformation. magnified image
Language: Английский
Citations
19
Advanced Synthesis & Catalysis, Journal Year: 2022, Volume and Issue: 364(16), P. 2735 - 2740
Published: July 1, 2022
Abstract A metal‐ and exogenous‐oxidant‐free oxidation‐induced oxyphosphorylation of alkenes alkynes with water for β‐ketophosphonates has been developed through the radical coupling under electrochemical conditions. This protocol is compatible a wide range alkenes, alkynes, diarylphosphorus derivatives, enables gram‐scale synthesis β‐ketophosphonates. The mechanistic study revealed that P radicals were generated via hydrogen atom transfer (HAT) event jointly mediated by tetrabutylammonium acetate anode oxidation process. magnified image
Language: Английский
Citations
17
The Journal of Organic Chemistry, Journal Year: 2022, Volume and Issue: 87(9), P. 6224 - 6236
Published: April 20, 2022
An efficient copper-catalyzed aerobic oxidative cross-dehydrogenative coupling reaction for the synthesis of multisubstituted phosphorylhydrazides from N,N-disubstituted hydrazines and hydrogen phosphoryl compounds is accomplished. The proceeds under mild conditions without addition any external oxidants bases. This work reported here represents a direct P(═O)-N-N bond formation with advantages being operationally simple, good functional group tolerance, high atom step economy. Furthermore, selected exhibit potential inhibitory activity against tumor cells, which can be used in field screening anticancer agents as new chemical entities.
Language: Английский
Citations
15
The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(9), P. 6106 - 6116
Published: April 18, 2024
An electrochemical oxidative cross-coupling strategy for the synthesis of N-sulfenylsulfoximines from sulfoximines and thiols was accomplished, giving diverse in moderate to good yields. Moreover, this can be extended construct N–P bond N-phosphinylated sulfoximines. With electrons as reagents, dehydrogenation reaction proceeds smoothly absence traditional redox reagents.
Language: Английский
Citations
3
Synlett, Journal Year: 2020, Volume and Issue: 31(19), P. 1894 - 1898
Published: June 16, 2020
Integrated electrochemical reactors in automated flow systems have been utilised for chalcogenophosphite formations. Multiple reactions can be performed using a programmed sequence fully autonomous way. Differently functionalised chalcogenophosphites efficiently synthesised short reaction times.
Language: Английский
Citations
20
European Journal of Organic Chemistry, Journal Year: 2021, Volume and Issue: 2021(26), P. 3743 - 3747
Published: June 25, 2021
Abstract An efficient and chemoselective synthesis of sulfoxides through the electrooxidation sulfides has been well developed. This protocol takes advantage electricity as terminal oxidant molecular oxygen water atom sources. A variety structurally diverse sulfoxide compounds are assembled in moderate to excellent yields. The scaled‐up reactions at 6–20 mmol show good practicability application potential this methodology. possible free radical mechanism proposed rationalize reaction procedure.
Language: Английский
Citations
17
Green Chemistry, Journal Year: 2024, Volume and Issue: 26(19), P. 10189 - 10195
Published: Jan. 1, 2024
A highly efficient and sustainable approach was developed for the construction of Si–O/Si–Si bonds, through electrochemical oxidative dehydrogenation hydrosilanes with O -nucleophiles or self-condensation hydrosilanes.
Language: Английский
Citations
2
Advanced Synthesis & Catalysis, Journal Year: 2020, Volume and Issue: 363(2), P. 464 - 469
Published: Dec. 5, 2020
Abstract The site‐selective functionalization of biologically important nitrogen‐containing heterocycles and related derivatives remains a challenging task. We report herein on the direct regiodivergent N1/C2 phosphorylation free indole derivatives. Cyclic voltammograms EPR data indicate that by utilizing different electrolyte‐mediated anodic oxidation to generate active species, diverse collection N1 C2 products could be obtained in moderate high yields under exogenous‐oxidant‐free metal‐catalyst‐free electrochemical conditions. In addition, N−P coupling was also found compatible with various alkylamines. magnified image
Language: Английский
Citations
18