Design, synthesis, and biological evaluation of novel (E)-1-arylethan-1-one O-((3-arylisoxazol-5-yl) methyl) oxime derivatives as potent non-nucleoside HBV inhibitors DOI
Yunhou Huang, Na Liu,

Qiuyue Ning

et al.

Journal of Molecular Structure, Journal Year: 2022, Volume and Issue: 1260, P. 132789 - 132789

Published: March 12, 2022

Language: Английский

Photocatalytic Regioselective Tandem Cyclization Protocol to Trifluoromethylated Pyrrolidones DOI Open Access
Panpan Wang, Yuting Leng,

Kaixia Sui

et al.

European Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 21, 2024

Abstract A new environmentally friendly and efficient strategy for preparing trifluoromethylated pyrrolidones has been developed. The process involves using visible light to induce radical cyclization of 1,5‐dienes with CF 3 SO 2 Na, resulting in excellent regioselectivity. This method uses less expensive easy‐to‐store trifluoromethylation reagents, making it an attractive option. Additionally, the can be easily modified preliminary mechanistic studies have presented.

Language: Английский

Citations

1
Copper-Catalyzed Cascade Annulation of Malonate-Tethered O-Acyl Oximes with Cyclic 1,3-Dicarbonyl Compounds for the Synthesis of Spiro-Pentacyclic Derivatives DOI
Kun Wang,

Hong-Rong Guan,

Wenlong Ren

et al.

The Journal of Organic Chemistry, Journal Year: 2021, Volume and Issue: 86(17), P. 12309 - 12317

Published: Aug. 9, 2021

A copper-catalyzed cascade annulation of malonate-tethered O-acyl oximes with cyclic 1,3-dicarbonyl compounds has been developed for the rapid synthesis spiro-pentacyclic derivatives. This reaction allows one-step formation five C–C/N/O bonds and an angular tricyclic core under very mild conditions shows excellent regioselectivity stereoselectivity.

Language: Английский

Citations

10
Switching the Regioselectivity Access to Pyrroles and Isoquinolines from Ketoxime Acetates and Ynals DOI Creative Commons

Tanggao Liu,

Fan Xu, Xiaojuan Liu

et al.

ACS Omega, Journal Year: 2020, Volume and Issue: 5(48), P. 31473 - 31484

Published: Nov. 23, 2020

A novel formal [3+2] and [4+2] annulation of ketoxime acetates ynals for the synthesis pyrroles isoquinolines has been developed. By simply switching catalyst solvent, reaction proceeds via two pathways. The reactions are achieved under mild conditions with broad substrate scope excellent regioselectivity.

Language: Английский

Citations

10
Copper-catalyzed efficient access to 2,4,6-triphenyl pyridinesviaoxidative decarboxylative coupling of aryl acetic acids with oxime acetates DOI
Varaprasad Bodala,

Karasala Bharat Kumar,

Vidavalur Siddaiah

et al.

New Journal of Chemistry, Journal Year: 2021, Volume and Issue: 45(34), P. 15205 - 15209

Published: Jan. 1, 2021

A simple and efficient strategy for the synthesis of 2,4,6- triphenyl pyridines has been developed through copper-catalysed oxidative decarboxylative coupling C(sp3) aryl acetic acids with oxime acetates using oxygen as a sole terminal oxidant.

Language: Английский

Citations

8
Design, synthesis, and biological evaluation of novel (E)-1-arylethan-1-one O-((3-arylisoxazol-5-yl) methyl) oxime derivatives as potent non-nucleoside HBV inhibitors DOI
Yunhou Huang, Na Liu,

Qiuyue Ning

et al.

Journal of Molecular Structure, Journal Year: 2022, Volume and Issue: 1260, P. 132789 - 132789

Published: March 12, 2022

Language: Английский

Citations

6