Six-membered ring systems: pyridines and benzo derivatives DOI

Jeanese C. Badenock

Progress in heterocyclic chemistry, Journal Year: 2023, Volume and Issue: unknown, P. 387 - 424

Published: Jan. 1, 2023

Language: Английский

Recent advances and future challenges in the synthesis of 2,4,6-triarylpyridines DOI
Dmitrii A. Shabalin

Organic & Biomolecular Chemistry, Journal Year: 2021, Volume and Issue: 19(38), P. 8184 - 8204

Published: Jan. 1, 2021

The present review is focused on recent advances (2015–present) in the synthesis of 2,4,6-triarylpyridines (also known as Kröhnke pyridines).

Language: Английский

Citations

17
TMSOTf-mediated Kröhnke pyridine synthesis using HMDS as the nitrogen source under microwave irradiation DOI Creative Commons
Chieh‐Kai Chan,

Yi-Hsiu Chung,

Cheng‐Chung Wang

et al.

RSC Advances, Journal Year: 2022, Volume and Issue: 12(13), P. 8263 - 8273

Published: Jan. 1, 2022

An efficient protocol for the preparation of pyridine skeletons has been successfully developed involving TMSOTf/HMDS (trifluoromethanesulfonic acid/hexamethyldisilane) system intermolecular cyclization chalcones under MW (microwave) irradiation conditions. This method provides a facile approach to synthesize 2,4,6-triaryl or 3-benzyl-2,4,6-triarylpyridines in good excellent yields. Interestingly, 2,6-diazabicyclo[2.2.2]oct-2-ene core was obtained by changing acid additive Sn(OTf)2, and desired product also confirmed using X-ray single-crystal diffraction analysis.

Language: Английский

Citations

9
TBAI/TBHP Catalyzed Synthesis of 2,4,6‐Trisubstituted Pyridines from Oxime Acetates Using Benzylamine as an Effective ArCO Surrogate under Transition Metal‐Free Conditions DOI
P. R. Lakshmi, Sunanda Kumari Kadiri, Varaprasad Bodala

et al.

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(12)

Published: March 25, 2024

Abstract An efficient TBHP/TBAI mediated strategy has been developed for the synthesis of 2,4,6‐trisubstitued pyridines from ketoxime acetates and benzylamines under metal‐free conditions first time. In this protocol benzylamine acts as an effective ArCO surrogate. This methodology features use inexpensive catalysts, avert additional ligands additives high functional group tolerance. Moreover, 5‐Lipoxygenase enzyme inhibitory activities were performed all synthesised compounds. Among 2,4,6‐trisubstituted 3fg, 3fa 3eg showed good activity.

Language: Английский

Citations

1
Copper-Catalyzed One-Pot Synthesis of 2,5-Disubstituted 1,3,4-Oxadiazoles from Arylacetic Acids and Hydrazides via Dual Oxidation DOI Creative Commons

Lekkala Chinnari,

Varaprasad Bodala,

Kumari Yettula

et al.

ACS Omega, Journal Year: 2022, Volume and Issue: 7(31), P. 27157 - 27163

Published: July 27, 2022

A simple and efficient protocol has been developed to access symmetrical unsymmetrical 2,5-disubstituted 1,3,4-oxadiazoles from arylacetic acids hydrazides via copper-catalyzed dual oxidation under an oxygen atmosphere. Oxidative decarboxylation of oxidative functionalization the imine C–H bond are key steps. This is first example synthesis through in one-pot. Avoidance expensive ligand high yield products advantageous features method.

Language: Английский

Citations

6
Iron‐Catalysed [3+3] Annulation of Oxime Acetates and Enaminones towards the Synthesis of Multi‐Substituted Pyridines DOI
Varaprasad Bodala,

Rajitha Lakshmi Podugu,

Kumari Yettula

et al.

Chemistry - An Asian Journal, Journal Year: 2022, Volume and Issue: 18(1)

Published: Dec. 3, 2022

A direct access to unsymmetrical and symmetrical multi-substituted pyridines has been accomplished via iron-catalysed [3+3] annulation of oxime acetates with enaminones. This protocol is featured by easily available starting materials, no requirement expensive additives ligands, operational simplicity, good tolerance diverse functional groups.

Language: Английский

Citations

6
Trans-ferulic acid valorization into stilbene derivatives via tandem decarboxylation/Heck coupling using Pd/Al-SBA-15 materials DOI
Georgiana Maties, Camino González‐Arellano, Rafael Luque

et al.

Materials Today Chemistry, Journal Year: 2022, Volume and Issue: 25, P. 100971 - 100971

Published: June 2, 2022

Language: Английский

Citations

5
Substituent-Oriented Synthesis of Substituted Pyridines/Pyrido[3,2-C]coumarins via Sequential Reactions of α-H and Me/Aryl Substituted Oxime Acetates and 3-Formylchromones DOI
Varaprasad Bodala,

Rajitha Lakshmi Podugu,

Kumari Yettula

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(18), P. 12957 - 12966

Published: Aug. 28, 2024

A facile one pot sequential and highly chemoselective synthesis of substituted pyridines/pyrido[3,2-

Language: Английский

Citations

0
Six-membered ring systems: pyridines and benzo derivatives DOI

Jeanese C. Badenock

Progress in heterocyclic chemistry, Journal Year: 2023, Volume and Issue: unknown, P. 387 - 424

Published: Jan. 1, 2023

Language: Английский

Citations

0