Acta Chimica Sinica,
Journal Year:
2022,
Volume and Issue:
80(8), P. 1152 - 1152
Published: Jan. 1, 2022
Dihydrobenzofuran
structural
units
are
widely
present
in
bioactive
natural
products,
and
therefore,
this
type
of
products
have
attracted
extensive
attention
from
synthetic
organic
chemists
pharmaceutical
chemists.In
recent
years,
enantioselective
formation
unit,
especially
its
C2
C3
vicinal
chiral
stereocenters,
has
always
been
one
challenging
problems
the
field
methodology.Among
some
methods,
construction
optically
active
dihydrobenzofuran
[3＋2]
cyclizations
phenols
(quinones)
olefins
via
asymmetric
catalysis
or
induction
by
auxiliaries
developed
rapidly.In
review,
we
summarized
progress
cyclization
reactions
with
different
types
catalysts
auxiliaries,
emphasis
on
understanding
control
stereoselectivies
these
methods.Meanwhile,
application
total
synthesis
dihydrobenzofurans
enabled
was
briefly
introduced.Finally,
future
development
trend
[3＋
2]
analyzed,
order
to
stimulate
emergence
highly
efficient
general
catalytic
system.
Organic & Biomolecular Chemistry,
Journal Year:
2023,
Volume and Issue:
21(8), P. 1821 - 1826
Published: Jan. 1, 2023
A
novel
[3
+
2]
cascade
reaction
of
aryl
acetate
with
1,4-dihydroxy-2-naphthoic
acid
ester
by
cooperative
catalysis
isothiourea
and
vanadium
is
developed.
The
key
step
the
that
C1-ammonium
enolates
generated
from
will
cycloadduct
to
1,4-naphthoquinone
intermediates.
3-Aryl-3H-benzofuranone
derivatives
can
be
prepared
in
medium
good
yields
under
mild
conditions.
The Chemical Record,
Journal Year:
2023,
Volume and Issue:
23(11)
Published: July 4, 2023
Enantiomerically
enriched
five-
and
six-membered
benzo
oxygen
heterocycles
are
privileged
architectures
in
functional
organic
molecules.
Over
the
last
several
years,
many
effective
methods
have
been
established
to
access
these
compounds.
However,
comprehensive
documents
cover
updated
methodologies
still
highly
demand.
In
this
review,
recent
transition
metal
catalyzed
transformations
lead
chiral
presented.
The
mechanism
chirality
transfer
or
control
processes
also
discussed
details.
New Journal of Chemistry,
Journal Year:
2024,
Volume and Issue:
48(18), P. 8243 - 8276
Published: Jan. 1, 2024
The
present
review
summarizes
the
recent
advances
(2018–2023)
in
stereoselective
annulation
involving
p
-benzoquinones
for
construction
of
fused,
spiro
and
bridged/cage
frameworks.
Chemistry - A European Journal,
Journal Year:
2024,
Volume and Issue:
30(44)
Published: June 1, 2024
A
copper-catalyzed
[3+2]
annulation
reaction
of
exocyclic
enamines/enol
ethers
with
1,4-benzoquinone
esters
has
been
developed,
providing
facile
access
to
N,O-spiroketals
and
spiroketals
under
mild
conditions
broad
substrate
scope
(26
examples,
71-94
%
yields).
Gram
scale
synthesis
chemical
transformations
demonstrated
that
this
method
is
potentially
useful
in
the
natural
products
drugs
containing
a
N,O-
spiroketal
moiety.
The
chiral
N,O-spiroketal
could
be
obtained
98
ee
after
recrystallization,
when
SaBOX
ligand
was
employed.
Acta Chimica Sinica,
Journal Year:
2022,
Volume and Issue:
80(8), P. 1152 - 1152
Published: Jan. 1, 2022
Dihydrobenzofuran
structural
units
are
widely
present
in
bioactive
natural
products,
and
therefore,
this
type
of
products
have
attracted
extensive
attention
from
synthetic
organic
chemists
pharmaceutical
chemists.In
recent
years,
enantioselective
formation
unit,
especially
its
C2
C3
vicinal
chiral
stereocenters,
has
always
been
one
challenging
problems
the
field
methodology.Among
some
methods,
construction
optically
active
dihydrobenzofuran
[3＋2]
cyclizations
phenols
(quinones)
olefins
via
asymmetric
catalysis
or
induction
by
auxiliaries
developed
rapidly.In
review,
we
summarized
progress
cyclization
reactions
with
different
types
catalysts
auxiliaries,
emphasis
on
understanding
control
stereoselectivies
these
methods.Meanwhile,
application
total
synthesis
dihydrobenzofurans
enabled
was
briefly
introduced.Finally,
future
development
trend
[3＋
2]
analyzed,
order
to
stimulate
emergence
highly
efficient
general
catalytic
system.
