Silver-catalyzed radical bisphosphonation reaction of maleimides with diarylphosphine oxides DOI
Wen Zhang,

Hong‐Li Ruan,

Zhijia Zhu

et al.

Tetrahedron Letters, Journal Year: 2023, Volume and Issue: 121, P. 154464 - 154464

Published: April 5, 2023

Language: Английский

SbCl3 Initiated Aerobic Phosphorylation of sp3 C−H Bond: A Facile Approach to α‐Phosphorylated Tetrahydroisoquinolines DOI
Yuemei Li, Shuwei Zhang,

Qiyuan Ma

et al.

Chemistry - An Asian Journal, Journal Year: 2022, Volume and Issue: 17(19)

Published: Aug. 10, 2022

An aerobic phosphorylation of N-aryltetrahydroisoquinolines was realized by SbCl3 initiated sp3 C-H bond functionalization, providing a series α-aminophosphonates in high yields. This work reveals that /O2 is an efficient and facile catalyst system to enable the antimony containing reagents might be potentially applied more general transformations.

Language: Английский

Citations

5
Palladium-Catalyzed Heck Cyclization with P(O)H Compounds to Construct Phosphinonyl-Azaindoline and -Azaoxindole Derivatives DOI

Yi-Yun Pan,

Xi-Wei Zhu,

Lei Shi

et al.

The Journal of Organic Chemistry, Journal Year: 2023, Volume and Issue: 88(14), P. 9843 - 9852

Published: July 11, 2023

We report herein a concise method for the construction of phosphinonyl-azaindoline and -azaoxindole derivatives via palladium-catalyzed cascade cyclization with P(O)H compounds. Various H-phosphonates, H-phosphinates, aromatic secondary phosphine oxides are all tolerated under reaction conditions. Furthermore, isomer families such as 7-, 5-, 4-azaindolines could be synthesized in moderate to good yields.

Language: Английский

Citations

1
Phenol-mediated decarboxylative proton transfer of γ-methylidene-δ-valerolactones: an approach towards (E)-2,4-pentadienoates DOI

Feng Wei,

Xiaoying Wu,

Ran Song

et al.

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(7), P. 2015 - 2020

Published: Jan. 1, 2024

A phenol-mediated decarboxylative proton transfer of γ-methylidene-δ-valerolactones (GMDVs) was developed, affording the target polysubstituted ( E )-2,4-pentadienoates in 99% yields with / Z up to 99 : 1.

Language: Английский

Citations

0
Alkyne Insertion Enabled Vinyl to Acyl 1,5‐Palladium Migration: Rapid Access to Substituted 5‐Membered‐Dihydrobenzofurans and Indolines DOI

Mingruo Ding,

Pengcheng Ou,

Xuening Li

et al.

Angewandte Chemie, Journal Year: 2023, Volume and Issue: 135(18)

Published: Feb. 21, 2023

Abstract “Through space” palladium/hydrogen shift is an efficient strategy to achieve selective functionalization of a specific remote C−H bond. Compared with relatively extensive exploited 1,4‐palladium migration process, the relevant 1,5‐Pd/H was far less investigated. We herein report novel pattern between vinyl and acyl group. Through pattern, rapid access 5‐membered‐dihydrobenzofuran indoline derivatives has been achieved. Further studies have unveiled unprecedented trifunctionalization (vinylation, alkynylation amination) phenyl ring through 1,5‐palladium relayed decarbonylative Catellani type reaction. A series mechanistic investigations DFT calculations provided insights into reaction pathway. Notably, it that in our case prefers stepwise mechanism involving Pd IV intermediate.

Language: Английский

Citations

0
Silver-catalyzed radical bisphosphonation reaction of maleimides with diarylphosphine oxides DOI
Wen Zhang,

Hong‐Li Ruan,

Zhijia Zhu

et al.

Tetrahedron Letters, Journal Year: 2023, Volume and Issue: 121, P. 154464 - 154464

Published: April 5, 2023

Language: Английский

Citations

0