Palladium-Catalyzed Asymmetric [3+2] Cycloaddition Reaction of Vinyl Cyclopropane with Electron-Deficient Dienes

Synlett, Journal Year: 2024, Volume and Issue: unknown

Published: March 18, 2024

Abstract Palladium-catalyzed asymmetric [3+2] cycloaddition reaction of vinyl cyclopropane and electron-deficient dienes was realized. The proceeded regioselectively on the distant C=C double bond dienes, mainly controlled by steric hindrance 5-substituent dienes. Chiral multi-substituted cyclopentanes bearing three functional groups (monosubstituted alkene, conjugated ester, cyano) continuous stereocenters were obtained in moderate to high yields, diastereoselectivities, enantioselectivities.

Language: Английский

Dicarbofunctionalization via C–C Bonds Cleavage

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Language: Английский

Selected Diastereoselective Transition Metal-Catalyzed Cyclizations

Elsevier eBooks, Journal Year: 2023, Volume and Issue: unknown, P. 335 - 356

Published: Dec. 19, 2023

Language: Английский