A facile route for highly enantioenriched six‐membered 1,4‐N,N‐ and N,O‐heterocycles from L‐serinate‐derived α‐bromoacetates DOI
So Jeong Lee,

Min Ji Park,

Seyeon Kim

et al.

Bulletin of the Korean Chemical Society, Journal Year: 2023, Volume and Issue: 44(12), P. 1025 - 1033

Published: Oct. 14, 2023

Abstract Preparation of highly enantioenriched six‐membered 1,4‐ N,N‐ and N,O‐ heterocycles has been developed through [4 + 2] heteroannulation α‐bromoacetates with 1,4‐binucleophiles. Two consecutive substitutions diastereoenriched L‐serinate‐derived provide convenient access to a wide range C‐aryl/aliphatic substituted up 99:1 er.

Language: Английский

Semi-heterogeneous g-C3N4/NaI dual catalytic C–C bond formation under visible light DOI
Haiyang Song, Jun Jiang, Chao Wu

et al.

Green Chemistry, Journal Year: 2023, Volume and Issue: 25(8), P. 3292 - 3296

Published: Jan. 1, 2023

The semi-heterogeneous g-C 3 N 4 /NaI dual catalytic system driven C–C bond formation between quinoxalin-2(1 H )-ones and arylhydrazines under blue light irradiation is reported for the first time.

Language: Английский

Citations

115
Multifunctional nano-cellulose aerogel for efficient oil–water separation: Vital roles of magnetic exfoliated bentonite and polyethyleneimine DOI

Rui Tang,

Shiqi Xu,

HU Ya

et al.

Separation and Purification Technology, Journal Year: 2023, Volume and Issue: 314, P. 123557 - 123557

Published: March 10, 2023

Language: Английский

Citations

35
Tropos Diphenylmethane-Based Phosphine–Phosphoramidite Ligands: Design, Synthesis, and Application in Catalytic Asymmetric Hydrogenation DOI
Zhong Zheng, Zheng‐Chao Duan, Xiang‐Ping Hu

et al.

Organic Letters, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 9, 2025

A series of chiral hybrid diphosphorus ligands incorporating a conformationally flexible tropos diphenylmethane-based phosphoramidite unit have been developed and evaluated in the Rh-catalyzed asymmetric hydrogenation 2-(1-arylvinyl)anilides α-enamides, leading to up >99% yield 99% enantiomeric excess. Preliminary results from comparative studies showcased extraordinary catalytic performance these phosphine–phosphoramidite ligands, with competency essentially superior those well-established regular rigid backbone.

Language: Английский

Citations

1
Recent advancements in visible-light-induced direct C(3)–H functionalization of quinoxalin-2(1H)-ones DOI Creative Commons

Xin Han,

Yifan Guo, Y. Hu

et al.

Green Synthesis and Catalysis, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

Language: Английский

Citations

3
A highly active and chemoselective homobimetallic ruthenium catalyst for one-pot reductive amination in water DOI
Gopal Deshmukh, Thakur Rochak Kumar Rana,

Nikita Yadav

et al.

Green Chemistry, Journal Year: 2023, Volume and Issue: 26(3), P. 1610 - 1626

Published: Dec. 13, 2023

A bimetallic Ru( ii ) complex efficiently catalyzes reductive amination of diverse substrates in water with the highest reported TONs and TOFs. Experimental DFT calculations point to a cooperative effect for increased efficiency at low catalyst loading (0.05 mol%).

Language: Английский

Citations

7
Transition-Metal-Catalyzed Asymmetric Reductive Amination and Amidation Cascade Reaction for the Synthesis of Piperazinones DOI

Rongrong Xie,

Huan Zhou,

Hui Lü

et al.

Organic Letters, Journal Year: 2022, Volume and Issue: 24(49), P. 9033 - 9037

Published: Dec. 6, 2022

An efficient enantioselective reductive amination and amidation cascade reaction has been developed. Catalyzed by iridium or rhodium complexes with the help of sets additives, coupling simple alkyl diamines α-ketoesters occurs smoothly to afford chiral cyclic piperazinone products. For disubstituted monosubstituted diamine substrates, corresponding reactions proceed through distinctive types intermediates thus require different transition metals achieve high enantioselectivity, namely, for former latter. In this transformation, applied highly modular phosphoramidite-phosphine hybrid ligands displayed preeminent versatility tunability.

Language: Английский

Citations

11
Cobalt-Catalyzed Enantioselective Reductive Amination of Ketones with Hydrazides DOI
Tiantian Chen, Yanhua Hu, Xuyang Tang

et al.

Organic Letters, Journal Year: 2023, Volume and Issue: 26(4), P. 769 - 774

Published: Dec. 4, 2023

An efficient cobalt-catalyzed asymmetric reductive amination of ketones with hydrazides has been realized, directly producing valuable chiral hydrazines in high yields and enantioselectivities (up to 98% enantiomeric excess).

Language: Английский

Citations

5
Metal-free cascade reactions for one-pot tetrahydroquinoxaline construction through nitroarene reduction and imine hydrogenation with water DOI
Yanqi Chen,

Subin Hao,

Lingfeng Yin

et al.

New Journal of Chemistry, Journal Year: 2024, Volume and Issue: 48(14), P. 6103 - 6108

Published: Jan. 1, 2024

A metal-free one-pot cascade process of imines with B 2 cat and water has been developed to construct dihydroquinoxalinones tetrahydroquinoxalines directly from readily available 2-nitroanilines or o -dinitrobenzenes α-ketoesters α-diketones.

Language: Английский

Citations

1
Sulfur-Promoted Access to 3-Arylquinoxalin-2-ones by Oxidative Coupling of o-Phenylenediamines with Arylacetates DOI

Le Anh Nguyen,

Thi Yen Nhi Tran, Quoc Anh Ngo

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(29), P. 6098 - 6102

Published: July 15, 2024

We disclose the synthesis of 3-arylquinoxalin-2-ones from o-phenylenediamines and readily available arylacetates. The method harnesses selective oxidative property elemental sulfur in presence amine base catalyst DMSO. reactions are operationally simple tolerate a wide range functional groups.

Language: Английский

Citations

1
Penta- versus hexa-coordinated iridium catalysts control the reactivity of the direct reductive amination between aliphatic amines and aliphatic ketones: a DFT-guided mechanism DOI Creative Commons

Hao Lin,

Longfei Li,

Lanbo Liu

et al.

Catalysis Science & Technology, Journal Year: 2024, Volume and Issue: 14(14), P. 3984 - 3995

Published: Jan. 1, 2024

The mechanism of the iridium-catalysed direct reductive amination between aliphatic partners was studied by DFT calculations leading to important changes in rate-determining step depending on nature ligand coordinating iridium.

Language: Английский

Citations

0