Manganese/Cobalt Bimetallic Relay Catalysis for Divergent Dehydrogenative Difluoroalkylation of Alkenes DOI
Zhong Tao,

Chengyihan Gu,

Yuhang Li

et al.

Angewandte Chemie, Journal Year: 2023, Volume and Issue: 135(42)

Published: Aug. 29, 2023

Abstract The involvement of manganese radical for halogen atom transfer (XAT) reactions has been esteemed as one reliable method but encountered with limited catalytic models. In this paper, a novel bimetallic relay catalysis Mn 2 (CO) 10 and cobaloxime developed divergent dehydrogenative difluoroalkylation alkenes using commercially available difluoroalkyl bromides. A wide range structurally diverse terminal, cyclic internal well tetrasubstituted are found to be good coupling partners deliver difluoroalkylated allylic products difluoromethylated products, accompanied the production H by‐product. This strategy features broad substrate scope, mild reaction conditions excellent functional group compatibility. Its success represents an important step‐forward expedite construction rich library products.

Language: Английский

Recent New Developments in Hofmann, Curtius, Schmidt, Lossen, and Related Reactions DOI
Masato Matsugi,

Takayuki Shioiri

Elsevier eBooks, Journal Year: 2023, Volume and Issue: unknown

Published: Jan. 1, 2023

Language: Английский

Citations

1
Synthesis of Difluoromethylated Alkenes via Copper‐Catalyzed Protodefluorination of β‐(Trifluoromethyl)styrenes DOI Creative Commons
Tao Dong, Yibin Ye, Yanhui Wang

et al.

Chemistry - An Asian Journal, Journal Year: 2023, Volume and Issue: 18(19)

Published: Aug. 18, 2023

Abstract Under typical copper‐catalyzed hydroboration conditions, β ‐(trifluoromethyl)styrenes demonstrate unusal reactivities by forming difluoromethylated alkenes via a net protodefluorination process. This is also distinct from trifluoromethyl with alkyl substituents where defluoroborylation products predominate.

Language: Английский

Citations

1
Manganese/Cobalt Bimetallic Relay Catalysis for Divergent Dehydrogenative Difluoroalkylation of Alkenes DOI
Zhong Tao,

Chengyihan Gu,

Yuhang Li

et al.

Angewandte Chemie, Journal Year: 2023, Volume and Issue: 135(42)

Published: Aug. 29, 2023

Abstract The involvement of manganese radical for halogen atom transfer (XAT) reactions has been esteemed as one reliable method but encountered with limited catalytic models. In this paper, a novel bimetallic relay catalysis Mn 2 (CO) 10 and cobaloxime developed divergent dehydrogenative difluoroalkylation alkenes using commercially available difluoroalkyl bromides. A wide range structurally diverse terminal, cyclic internal well tetrasubstituted are found to be good coupling partners deliver difluoroalkylated allylic products difluoromethylated products, accompanied the production H by‐product. This strategy features broad substrate scope, mild reaction conditions excellent functional group compatibility. Its success represents an important step‐forward expedite construction rich library products.

Language: Английский

Citations

1