Chemical Reviews,
Journal Year:
2024,
Volume and Issue:
124(10), P. 6643 - 6689
Published: May 9, 2024
1,1′-Bi-2-naphthol
(BINOL)
has
been
extensively
used
as
the
chirality
source
in
fields
of
molecular
recognition,
asymmetric
synthesis,
and
materials
science.
The
direct
electrophilic
substitution
at
aromatic
rings
optically
active
BINOL
developed
one
most
convenient
strategies
to
structurally
modify
for
diverse
applications.
High
regioselectivity
achieved
reaction
with
electrophiles.
Depending
upon
conditions
patterns,
various
functional
groups
can
be
introduced
specific
positions,
such
6-,
5-,
4-,
3-positions,
BINOL.
Ortho-lithiation
3-position
directed
by
2-position
have
prepare
3-
3,3′-substituted
BINOLs.
use
transition
metal-catalyzed
C–H
activation
also
explored
functionalize
3-,
7-positions.
These
regioselective
substitutions
allowed
construction
tremendous
amount
derivatives
fascinating
structures
properties
reviewed
this
article.
Examples
applications
BINOLs
varying
catalysis,
chiral
sensing
are
provided.
Angewandte Chemie International Edition,
Journal Year:
2024,
Volume and Issue:
unknown
Published: July 18, 2024
Abstract
Despite
impressive
advances
in
the
construction
of
enantioenriched
silacarbocycles
featuring
silicon‐stereogenic
centers
via
a
selection
well‐defined
sila‐synthons,
development
more
convenient
and
economic
method
with
readily
available
starting
materials
is
significantly
less
explored
remains
considerable
challenge.
Herein,
we
report
first
example
copper‐catalyzed
sequential
hydrosilylation
accessible
methylenecyclopropanes
(MCPs)
primary
silanes,
affording
an
efficient
route
to
wide
range
chiral
silacyclopentanes
bearing
consecutive
silicon‐
carbon‐stereogenic
excellent
enantio‐
diastereoselectivities
(generally
≥98
%
ee,
>25
:
1
dr).
Mechanistic
studies
reveal
that
these
reactions
combine
intermolecular
ring‐opening
aryl
MCPs
intramolecular
asymmetric
resultant
Z
/
E
mixture
homoallylic
silanes.
Journal of the American Chemical Society,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 21, 2024
A
ligand-controlled
regiodivergent
and
enantioselective
ring
expansion
of
benzosilacyclobutenes
with
internal
naphthyl
alkynes
has
been
achieved
by
adjusting
the
ligand
cavity
size.
The
(
Chinese Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
43(10), P. 3508 - 3508
Published: Jan. 1, 2023
Due
to
the
widespread
application
of
various
organosilicon
compounds
in
material
science,
electronic
devices
and
pharmaceutical
research,
it
is
great
significance
develop
green
efficient
synthetic
methods
for
diverse
silicon-containing
molecules.Silacyclobutane
an
important
kind
small-membered
rings,
which
exhibits
unique
reactivities
under
transition
metal
catalysis
cleave
C-Si
bond
driven
by
inherent
ring
strain
Lewis
acidity.The
resulting
Si-M
species
can
then
be
transformed
into
compounds.Herein,
recent
advances
Pd,
Rh,
Ni-catalyzed
cleavage
reactions
silacyclobutanes
are
summarized
detail,
mechanism
development
tendency
such
briefly
discussed.
Organic Letters,
Journal Year:
2024,
Volume and Issue:
26(29), P. 6142 - 6147
Published: July 12, 2024
Selective
dehydrogenative
C-H
silylation
is
one
of
the
most
powerful
tools
to
synthesize
silacycles.
Herein,
we
developed
Ru-catalyzed
sequential
hydrosilylation/C-H
allyl-indoles
and
O-H/C-H
pyrrole
phenols.
Both
six-membered
indole
silacycles
silyl
ether
cycles
were
successfully
synthesized
with
good
functional
group
tolerance.
Furthermore,
RuHCl(CO)(PPh
Green Synthesis and Catalysis,
Journal Year:
2023,
Volume and Issue:
5(3), P. 205 - 210
Published: Sept. 7, 2023
Asymmetric
ring-expansion
reactions
of
silacyclobutanes
(SCBs)
with
alkynes
have
evolved
as
one
the
powerful
protocols
for
construction
silicon-stereogenic
compounds.
However,
achievement
highly
enantioselective
annulation
SCBs
terminal
remains
a
challenge.
Herein,
we
report
rhodium-catalyzed
asymmetric
reaction
alkynes,
which
relies
on
newly
identified
chiral
sulfinamide
phosphine
ligand
Ming-Phos.
This
catalytic
system
exhibits
unique
effects
under
mild
conditions,
leading
to
direct
synthesis
structurally
diverse
silacycles
in
moderate
good
yields
high
enantioselectivities
(up
95%
ee).
Chemistry - A European Journal,
Journal Year:
2023,
Volume and Issue:
29(70)
Published: Sept. 23, 2023
Abstract
Silaspiranes
bearing
a
spiro‐silicon
center
are
promising
ring
frameworks
for
the
synthesis
of
novel
spirocyclic
molecules
possessing
unique
properties.
Development
efficient
methods
towards
these
structures
has
therefore
attracted
considerable
attentions
synthetic
chemists.
This
minireview
highlights
representative
advances
in
field,
and
is
categorized
into
four
parts
according
to
formation
strategies:
cyclization,
annulation,
expansion
cycloaddition.
Chinese Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
43(10), P. 3388 - 3388
Published: Jan. 1, 2023
In
the
past
two
decades,
organosilicon
compounds
bearing
silicon-stereogenic
centers
have
attracted
extensive
attention
in
fields
of
organic
synthesis,
materials,
and
drug
design.However,
expansion
these
has
been
greatly
restricted
by
limited
source
compounds.Therefore,
development
highly
efficient
selective
asymmetric
catalytic
methods
to
obtain
chiral
with
is
a
challenging
task
that
needs
be
solved
urgently.The
latest
research
progress
on
new
reaction
systems
for
synthesis
center
containing
organosilanes
since
2011
mainly
summarized.
