Tetranuclear N-Heterocyclic Carbene Palladium Acetate—The Fast-Initiating Precatalyst of Suzuki Coupling DOI Open Access
Sylwia Ostrowska, Szymon Rogalski, Maciej Kubicki

et al.

Catalysts, Journal Year: 2024, Volume and Issue: 14(11), P. 836 - 836

Published: Nov. 20, 2024

A tetranuclear N-heterocyclic palladium carbene acetate, characterised by a [Pd]/[NHC] = 2/1 ratio, was synthesised and shown to be catalytically active in Suzuki coupling. Single crystal XRD studies of the complex revealed its unprecedented geometry, with presence three coordinated centres. The catalytic activity is significantly higher than that analogues containing same ligand. Preliminary have been carried out determine properties complex.

Language: Английский

N-heterocyclic carbene-palladium complex immobilized on Co-MOF 74 microrods as a highly selective catalyst for Suzuki–Miyaura cross-coupling DOI Creative Commons
Duygu Hacıefendioğlu, Alï Tuncel

Reaction Kinetics Mechanisms and Catalysis, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 2, 2025

Language: Английский

Citations

1
Pd–NHC (NHC = N-Heterocyclic Carbene)-Catalyzed B-Alkyl Suzuki Cross-Coupling of 2-Pyridyl Ammonium Salts by N–C Activation: Application to the Discovery of Agrochemical Molecular Hybrids DOI
Yanqing Gao,

Yuge Hu,

Jiuhui Ye

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(11), P. 2309 - 2314

Published: March 11, 2024

2-Alkylpyridines are a privileged scaffold throughout the realm of organic synthesis and play key role in natural products, pharmaceuticals, agrochemicals. Herein, we report first B-alkyl Suzuki cross-coupling 2-pyridyl ammonium salts to access functionalized 2-alkylpyridines. The use well-defined, operationally simple Pd-NHCs permits for an exceptionally broad scope challenging C–N with organoboranes containing β-hydrogen, representing novel method discovery highly sought-after molecules plant protection.

Language: Английский

Citations

3
Earth‐Abundant Recyclable Magnetic Iron Oxide Nanoparticles for Green‐light Mediated C−H Arylation in Heterogeneous Phase DOI

Tanumoy Mandal,

Ashwin Chaturvedi,

Aznur Azim

et al.

Chemistry - A European Journal, Journal Year: 2024, Volume and Issue: 30(44)

Published: May 24, 2024

A magnetically isolable iron oxide nanoparticles is introduced as an efficient heterogeneous photocatalyst for non-directed C-H arylation employing aryl diazonium salts the precursors. This first-row transition metal-based revealed versatile activities and applicable to a wide range of substrates, demonstrating brilliant efficacy superior recyclability. Detailed catalytic characterization describes physical properties redox behavior Fe-catalyst. Adequate control experiments helped establish radical-based mechanism arylation.

Language: Английский

Citations

3
Full-color emission of fluorinated benzothiadiazole-based D–A–D fluorophores and their bioimaging applications DOI Creative Commons
Sihong Chen,

Xi-Ying Cao,

Pengtao Hu

et al.

Materials Advances, Journal Year: 2023, Volume and Issue: 4(24), P. 6612 - 6620

Published: Jan. 1, 2023

By modulating donor and acceptor units, serial fluorinated benzothiadiazole-based full-color fluorophores with various luminescence properties, such as DSE, ACQ AIEE effects, are developed. Importantly, red emitter 3m can be used in bioimaging.

Language: Английский

Citations

6
Purple Light-Promoted Coupling of Bromopyridines with Grignard Reagents via SET DOI
Xingyu Lei, Yihan Wang, Shanshan Ma

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(10), P. 7148 - 7155

Published: May 8, 2024

Alkyl- and arylpyridines 2,2′-bipyridines are conventionally prepared by Minisci reactions of pyridines transition metal-catalyzed coupling halopyridines. Herein, purple light-promoted radical 2- or 4-bromopyridines with Grignard reagents in Et2O a mixture tetrahydrofuran regular glassware without the need for metal catalyst were disclosed first time. Methyl, primary secondary alkyl, cycloalkyl, aryl, heteroaryl, pyridyl, alkynyl compatible protocol. As result, alkyl- easily prepared. Single electron transfer from reagent to bromopyridine was stimulated light. An extruded dimerization worked as catalyst. Light on/off experiments indicated that constant irradiation required product formation. Studies clock substrates verified involvement pyridyl noninvolvement an alkyl aryl reagent. The available proof supports photoinduced SRN mechanism new reactions.

Language: Английский

Citations

2
A Review on the Recent Progress of Layered Double Hydroxides (LDHs)-based Catalysts for Heterocyclic Synthesis DOI

Khadija El Farouki,

Marieme Kacem,

Mustapha Dib

et al.

Current Organocatalysis, Journal Year: 2023, Volume and Issue: 11(2), P. 154 - 174

Published: Oct. 31, 2023

Over the past decade, heterocyclic compounds and their derivatives have emerged as promising substances with potential pharmacological applications due to interesting biological properties. The significance of in drug discovery development is evident from fact that a majority drugs pharmaceutical market incorporate active or ingredients. Various synthetic methods advancements been devised prepare these using diverse catalysts under mild conditions. Layered double hydroxides (LDHs)-based materials gained considerable attention across different fields, usability can be significantly enhanced via selection metal cations, molar ratios, surface complexation, intercalation modifications. synthesis application LDH-based garnered increasing interest exceptional Moreover, found extensive use heterogeneous numerous compounds. This review presents latest developments catalytic solid compounds, covering literature published 2018 2023. Keywords: materials, catalysis, catalyst, synthesisLayered

Language: Английский

Citations

4
Synthesis of Functionalized Indoles by an Iridium-Catalyzed N–H Insertion Cascade: Nucleophilic Cyclization of Naphthylamines with α-Diazocarbonyl Compounds DOI
Xiaogang Wang, Chi Yang, Di Chen

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 28, 2024

A novel iridium-catalyzed [3 + 2] annulation of naphthylamines and α-diazocarbonyl compounds was developed for the rapid assembly densely functionalized indoles. This new catalytic process represents first example a cascade intramolecular nucleophilic cyclization by N-H insertion amines. Various could be obtained in high yields with excellent functional group tolerance. The reaction affords valuable indole derivatives, enabling expedient access to heterocyclic analogues not easily accessible other methods.

Language: Английский

Citations

1
Structural and catalytic studies of Six-Membered amino N-Heterocyclic carbene palladium (II) complexes with a triazine backbone for Suzuki coupling reaction DOI
Ming‐Tsz Chen, Cheng‐Chun Huang, Ching‐Wei Chang

et al.

Inorganica Chimica Acta, Journal Year: 2024, Volume and Issue: unknown, P. 122466 - 122466

Published: Nov. 1, 2024

Language: Английский

Citations

0
Weakly-Activated Phenol Derivatives as New Green Electrophilic Partners in Suzuki–Miyaura and Related C-C Couplings DOI Creative Commons

Jules Perney,

Alexandre Humblot-Negri,

Carlos Vaca‐García

et al.

Molecules, Journal Year: 2024, Volume and Issue: 30(1), P. 51 - 51

Published: Dec. 26, 2024

In recent years, there has been growing interest in the development of greener alternatives to traditional reagents used carbon–carbon coupling reactions, particularly response environmental concerns. The commonly aryl halides, despite being highly reactive Suzuki–Miyaura (SMC), pose significant risks. As a result, research shifted towards exploring use phenols, which are widely accessible and environmentally benign. However, phenols considerably less due poor leaving group properties hydroxyl group, necessitating prior activation facilitate their reactions. This work aims review investigations on strategies for focusing application related C-C couplings. addition, exploration potential conducting step “in situ” will also be discussed. We hope that this article pave way more sustainable efficient methodologies, addressing both ecological practical challenges organic synthesis.

Language: Английский

Citations

0
Tetranuclear N-Heterocyclic Carbene Palladium Acetate—The Fast-Initiating Precatalyst of Suzuki Coupling DOI Open Access
Sylwia Ostrowska, Szymon Rogalski, Maciej Kubicki

et al.

Catalysts, Journal Year: 2024, Volume and Issue: 14(11), P. 836 - 836

Published: Nov. 20, 2024

A tetranuclear N-heterocyclic palladium carbene acetate, characterised by a [Pd]/[NHC] = 2/1 ratio, was synthesised and shown to be catalytically active in Suzuki coupling. Single crystal XRD studies of the complex revealed its unprecedented geometry, with presence three coordinated centres. The catalytic activity is significantly higher than that analogues containing same ligand. Preliminary have been carried out determine properties complex.

Language: Английский

Citations

0