Visible-light-promoted azidation/arylation of unactivated alkenes with Togni-N3 via electrondonor–acceptor complexes DOI
Peng Xie, Yue Gao,

Chenqi Wu

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 30, 2024

A visible-light-promoted azidation/arylation of unactivated alkenes with Togni-N 3 toward a series azidated pyrrolo[1,2- ]indoles via an EDA complex as the key intermediate.

Language: Английский

Photochemical dearomative skeletal modifications of heteroaromatics DOI Creative Commons
Peng Ji, Kuaikuai Duan, Menglong Li

et al.

Chemical Society Reviews, Journal Year: 2024, Volume and Issue: 53(12), P. 6600 - 6624

Published: Jan. 1, 2024

Dearomatization has emerged as a powerful tool for rapid construction of 3D molecular architectures from simple, abundant, and planar (hetero)arenes. The field evolved beyond simple dearomatization driven by new synthetic technology development. With the renaissance photocatalysis expansion activation mode, last few years have witnessed impressive developments in innovative photochemical methodologies, enabling skeletal modifications dearomatized structures. They offer truly efficient useful tools facile highly complex structures, which are viable natural product synthesis drug discovery. In this review, we aim to provide mechanistically insightful overview on these innovations based degree alteration, categorized into dearomative functionalization editing, highlight their utilities.

Language: Английский

Citations

14
Decatungstate‐Photocatalyzed Diastereoselective Dearomative Hydroalkylation of Indoles DOI Creative Commons

Emeric Montinho‐Inacio,

Damien Bouchet, Wei‐Yang Ma

et al.

European Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 27(22)

Published: April 16, 2024

Abstract In this study, we present an efficient and straightforward dearomative hydroalkylation of indoles. By utilizing alkanes or ethers as alkyl radical sources employing TBADT a cost‐effective photocatalyst for direct hydrogen atom transfers (HAT), achieved successful conversion these heterocyclic derivatives into 2‐alkylindolines with good to excellent yields high diastereoselectivity under mild reaction conditions.

Language: Английский

Citations

8
Photoredox/NHC cooperative catalysis for alkylacylation of styrenes: An alternative method for the synthesis of γ-aminoketones DOI

Ke-Yang Yu,

Fu Cheng,

Dong-Sen Duan

et al.

Tetrahedron Letters, Journal Year: 2025, Volume and Issue: 156, P. 155450 - 155450

Published: Jan. 8, 2025

Language: Английский

Citations

1
Visible Light Photoredox-Catalyzed Formyl/Carboxylation of Activated Alkenes with Glyoxylic Acid Acetals and CO2 DOI

Yang Han,

Yang Yao,

Qi Yang

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(20), P. 4194 - 4199

Published: May 15, 2024

A photoredox-catalyzed sequential α-formyl/carboxylation of alkenes with glyoxylic acid acetals and CO

Language: Английский

Citations

6
Advances in photochemical/electrochemical synthesis of heterocyclic compounds from carbon dioxide DOI
Yuyang Xie, Ying‐Ming Pan

Green Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

This paper reviews progress in the photochemical/electrochemical construction of heterocyclic compounds using CO 2 , differentiating between various reaction types and elucidating their underlying mechanisms as well potential applications.

Language: Английский

Citations

5
Visible-Light-Promoted Cascade Carboxylation/Arylation of Unactivated Alkenes with CO2 for the Synthesis of Carboxylated Indole-Fused Heterocycles DOI

Yang Han,

Qi Yang,

Yang Yao

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(30), P. 6341 - 6346

Published: July 18, 2024

Described here is a visible-light-promoted cascade carboxylation/arylation of indole-tethered unactivated alkenes with CO

Language: Английский

Citations

4
Visible-light-promoted trifluoromethylation/arylation of unactivated alkenes with Togni-CF3 for the synthesis of trifluoromethylated pyrrolo[1,2–a]indoles DOI

Hongni Qin,

Yong Zhang, Song Sun

et al.

Tetrahedron Letters, Journal Year: 2025, Volume and Issue: unknown, P. 155468 - 155468

Published: Jan. 1, 2025

Language: Английский

Citations

0
Copper-PMHS System-Enabled Reductive Cyclization of o-Aminobenzamides with CO2 as a Single-Carbon Synthon DOI
Jiang Nan, Lu Zhang,

Rui Cao

et al.

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 18, 2025

Chemical utilization of carbon dioxide (CO2) has emerged as a sustainable access for synthesizing high-value chemicals. Continuously designing the more practical reaction systems is large importance. Herein, an unprecedented and powerful copper-PMHS reductive system o-aminobenzamides with CO2 disclosed. Synthetically, diverse range quinazolinones (>70 examples) are rapidly assembled excellent functional group tolerance in good yields. Moreover, building other types heterocycles such benzothiazoles benzimidazoles also allowable. Mechanistically, differing from reported carbonylation cases, this finding represents scarce example single-carbon atom synthon PMHS system.

Language: Английский

Citations

0
Dearomatization of Aromatic Compounds: A Decade Review DOI
Jianmin Chen, Wenhao Zhang, Dayun Huang

et al.

Asian Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: May 28, 2025

Abstract Dearomatization offers an efficient strategy for directly converting arenes into cyclic molecules. In this review, we discuss representative examples of dearomatization reactions through five modes: (1) radical dearomatization, (2) halofunctionalization‐dearomatization, in which three‐membered intermediates were frequently involved, (3) nucleophilic mainly about electron‐rich arenes, (4) oxidative and (5) reductive dearomatization. Compared to heteroarenes, simple benzene are more challenging participate reactions. recent years, fewer reports have focused on benzene. Heteroarenes, inherently or easily activated, tend undergo readily. This review highlights a decade progress including indoles, benzofurans, benzothiophenes, thiophenes, furans, naphthols, naphthalenes, quinolines, pyridines, nitrobenzenes, benzenes. It also analyzes their mechanisms strategies. We hope will aid future research field.

Language: Английский

Citations

0
Advances in the Synthesis of Carboxylic Acid by Photochemical Conversion of CO2 DOI
Pan‐Feng Yuan,

Can‐Ming Zhu,

Qingyuan Meng

et al.

Chinese Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 44(10), P. 2997 - 2997

Published: Jan. 1, 2024

Language: Английский

Citations

2