Recent Advances in Nonprecious Metal Catalysis DOI
David J. Bernhardson, Aran K. Hubbell, Robert A. Singer

et al.

Organic Process Research & Development, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 7, 2024

As the field of nonprecious metal catalysis continues to expand, we pursue a review series covering selected transformations in this area over short time interval highlight practical advancements. We seek raise awareness both current art and need continue development toward broader applications earth-abundant metals chemical pharmaceutical industries.

Language: Английский

Two 1-D, 2-D, and 3-D silver(I) complexes: crystallography, spectroscopy, bacteriostatic activity studies and TD/DFT calculation, Hirshfeld surface analysis DOI

Lan‐Qin Chai,

Tiantian Chen, Xiang Huang

et al.

Journal of Molecular Structure, Journal Year: 2025, Volume and Issue: unknown, P. 141972 - 141972

Published: March 1, 2025

Language: Английский

Citations

1
Ruthenium–Hydride Complexes Facilitated Sustainable Synthesis of Isoxazolones via Acceptorless Dehydrogenative Annulation of Alcohols DOI

Clinton Savarimuthu Selvan,

Veerappan Tamilthendral, Rengan Ramesh

et al.

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

A streamlined strategy for the one-pot synthesis of isoxazolone analogues has been developed through an acceptorless dehydrogenative annulation (ADA) pathway by employing new Ru(II) hydride complexes as effective catalysts. New (C1–C3) tailored with N̂O chelating carbazolone benzhydrazone ligands were synthesized and their formation was confirmed using analytical spectral techniques including FT-IR NMR. The structural configuration featuring octahedral geometry around ion precisely determined single-crystal X-ray diffraction analysis. Further, catalytic efficacy titled established facile productive derivatives from a diverse range benzyl alcohols, methyl acetoacetate/ethyl benzoylacetate hydroxylamine hydrochloride, generating excellent yields up to 93% under well-suited mild conditions 1 mol % catalyst loading. sequence time-dependent control experiments unveiled ADA route, indicating initial generation 4-methoxy benzaldehyde intermediate followed 3-phenylisoxazol-5(4H)-one, accompanied release water hydrogen byproducts. Gram-scale compound indicates industrial relevance our synthetic strategy. short medicinally active androgen antagonist illustrates utility present protocol.

Language: Английский

Citations

0
Ruthenium(II)-Catalyzed Synthesis of N-Heterocycles via Ac-ceptorless Dehydrogenative Condensation DOI
Chong Zhang, Bowen Hu, Dafa Chen

et al.

Journal of Organometallic Chemistry, Journal Year: 2025, Volume and Issue: 1029, P. 123545 - 123545

Published: Jan. 31, 2025

Language: Английский

Citations

0
NNN-Ru complexes catalyzed β-methylation of alcohols using methanol via borrowing hydrogen approach DOI

Mengxuan Bai,

Ziying Zhong, Zhiqiang Hao

et al.

Journal of Catalysis, Journal Year: 2025, Volume and Issue: unknown, P. 116026 - 116026

Published: Feb. 1, 2025

Language: Английский

Citations

0
A Comprehensive Investigation of Diverse Synthetic Methodologies for Constructing Quinoline Frameworks: A Critical Overview DOI Open Access
Nagesh Dhanaji Chavan,

Balamurugan Shanmugavel,

Yasinalli Tamboli

et al.

ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(10)

Published: March 1, 2025

Abstract Recently, quinoline has emerged as a critical heterocyclic structure, attracting attention for its diverse industrial and synthetic organic chemistry applications. This compound is essential developing novel lead compounds in drug discovery extensively studied therapeutic derivatives medicinal chemistry. An extensive body of literature details the methodologies synthesizing this key scaffold functionalization to enhance biological efficacy. Numerous synthesis protocols have been documented, highlighting significance ongoing chemical research. These include various strategies, such transition metal‐catalyzed reactions environmentally sustainable processes, which are crucial constructing functionalizing derivatives. review aims systematically examine procedures findings, addressing limitations these pathways their environmental impacts. Additionally, curated selection quinolines will be presented.

Language: Английский

Citations

0
Nickel–PNN catalysed sustainable synthesis of polysubstituted quinolines under microwave irradiation DOI
Manali A. Mohite, Sonu Sheokand, Maravanji S. Balakrishna

et al.

Catalysis Science & Technology, Journal Year: 2024, Volume and Issue: 14(20), P. 5959 - 5969

Published: Jan. 1, 2024

This manuscript describes the synthesis of triazolyl-pyridine-based pincer cationic and neutral nickel complexes their application in microwave-assisted quinolines.

Language: Английский

Citations

2
Potent pincer-zinc catalyzed homogeneous α-alkylation and Friedländer quinoline synthesis reaction of secondary alcohols/ketones with primary alcohols DOI
Debashis Jana, Sima Roy,

Srijita Naskar

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: 22(31), P. 6393 - 6408

Published: Jan. 1, 2024

Herein, we describe an air- and moisture-stable, homogeneous zinc catalyst stabilised using electron deficient N^N^N pincer-type ligand.

Language: Английский

Citations

1
Cu–ABNO Catalyst for the Synthesis of Quinolines and Pyrazines via Aerobic Double Dehydrogenation of Alcohols DOI
Shivali Hans,

Mohd Adham,

Manas Khatua

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 28, 2024

In this report, a new imidazole- and amide-functionalized pincer-like Cu(II) complex (1) was synthesized characterized. By employing 1 9-azabicyclo[3.3.1]nonane NH-Oxyl (ABNOH), catalytic protocol for alcohol oxidation the subsequent oxidation-triggered synthesis of quinolines pyrazines were explored. Alcohols such as 2-aminoaryl alcohols also oxidized efficiently. As carbonyls from 2-arylaminobenzyl secondary are synthons quinolines, we explored their directly alcohols. The quite efficient completed reaction in only ∼5–10 h. Combinations (a) primary with or ketones (b) found to be very effective quinolines. successful various 1,2-diols 1,2-diaminobenzenes 10 Mechanistic investigations showed that generated acted an active catalyst: it activated O2 subsequently cooperation N-Oxyl (ABNO•) α-CH hydrogen coordinated alkoxide. Then, Cu(II)/Cu(I) reduction led formation carbonyl compounds, which via successive C–C/C–N coupling reactions resulted heterocycles presence KOtBu 1.

Language: Английский

Citations

1
Chromium Catalyzed Sustainable C-C and C-N Bond Formation: C-Alkylation and Friedländer Quinoline Synthesis Using Alcohols DOI

Vaishnavi Atreya,

Sachin Jalwal, Subrata Chakraborty

et al.

Dalton Transactions, Journal Year: 2024, Volume and Issue: 54(3), P. 1212 - 1221

Published: Nov. 18, 2024

A complex of earth-abundant chromium mediates C–C and C–N bond formation via alcohol dehydrogenation, forming C -alkylated ketones secondary alcohols, as well quinoline synthesis by a modified Friedländer reaction.

Language: Английский

Citations

0
Recent Advances in Nonprecious Metal Catalysis DOI
David J. Bernhardson, Aran K. Hubbell, Robert A. Singer

et al.

Organic Process Research & Development, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 7, 2024

As the field of nonprecious metal catalysis continues to expand, we pursue a review series covering selected transformations in this area over short time interval highlight practical advancements. We seek raise awareness both current art and need continue development toward broader applications earth-abundant metals chemical pharmaceutical industries.

Language: Английский

Citations

0