Synthesis of Amides Using Triazine Esters as Stable Acylation Reagents DOI

Synfacts, Journal Year: 2024, Volume and Issue: 20(04), P. 0348 - 0348

Published: March 13, 2024

Key words amides - iron-mediated amidation triazines nitroarenes

Language: Английский

Nickel-catalyzed cross-electrophile coupling of unactivated (hetero)aryl sulfone with aryl bromide DOI
Wenxin Li,

Bo‐Jie Huo,

Jie-Ying Huang

et al.

Journal of Catalysis, Journal Year: 2024, Volume and Issue: 430, P. 115359 - 115359

Published: Feb. 1, 2024

Language: Английский

Citations

10
Hydroxylation of Aryl Sulfonium Salts for Phenol Synthesis under Mild Reaction Conditions DOI Creative Commons

Xuan-Bo Hu,

Qian-Qian Fu,

Xueying Huang

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(4), P. 831 - 831

Published: Feb. 13, 2024

Hydroxylation of aryl sulfonium salts could be realized by utilizing acetohydroxamic acid and oxime as hydroxylative agents in the presence cesium carbonate a base, leading to variety structurally diverse hydroxylated arenes 47–95% yields. In addition, reaction exhibited broad functionality tolerance, range important functional groups (e.g., cyano, nitro, sulfonyl, formyl, keto, ester) well amenable mild conditions.

Language: Английский

Citations

10
Nickel-catalyzed cross-electrophile couplings of aryl fluorosulfates with vinyl chlorosilanes DOI

Jin-He Na,

Hong-Jian Du,

Jia-Wen Jing

et al.

Journal of Catalysis, Journal Year: 2024, Volume and Issue: 437, P. 115636 - 115636

Published: July 6, 2024

Language: Английский

Citations

9
Direct Cross-Couplings of Aryl Nonaflates with Aryl Bromides under Nickel Catalysis DOI
Hao Xu,

Jia-Wen Jing,

Yubing Chen

et al.

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 30, 2025

The direct cross-couplings of aryl nonaflates with bromides could be successfully accomplished by utilizing nickel as the catalyst, magnesium metal mediator, and lithium chloride additive. reactions proceeded efficiently in THF at room temperature to produce desired biaryls moderate good yields, showing both a reasonable substrate scope functional group tolerance. Additionally, an equally performance realized when reaction was subjected scale-up synthesis. Preliminary study suggested that presumably proceeds through situ formation arylmagnesium reagent key intermediate.

Language: Английский

Citations

1
Cross-Electrophile Couplings of Benzyl Sulfonium Salts with Thiosulfonates via C–S Bond Activation DOI

Xuan-Bo Hu,

Yuwei Chen, Chenlong Zhu

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(18), P. 13601 - 13607

Published: Sept. 4, 2024

A zinc-mediated cross-electrophile coupling of benzyl sulfonium salts with thiosulfonates via C-S bond cleavage was achieved. The reductive thiolation proceeded well under transition metal-free conditions to afford the desired sulfides in good yields, exhibiting both broad substrate scope and functionality tolerance. In addition, reaction could be applied use selenosulfonate as an effective selenylation agent subjected scale-up synthesis.

Language: Английский

Citations

5
Molybdenum‐Catalyzed One‐Pot Multi‐Step Synthesis of N‐Polyheterocycles from Nitroarenes and Glycols DOI Creative Commons
Sara Gómez‐Gil, Nuria Cases, Raquel Hernández‐Ruiz

et al.

European Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 27(18)

Published: March 16, 2024

Abstract We report the efficient, sustainable one‐pot synthesis of a wide variety N ‐polyheterocycles, such as imidazo‐quinolines and quinoxalines, furoquinolines, from easily available nitroaromatics glycols via molybdenum catalytic domino reduction‐imine formation‐intramolecular cyclization‐oxidation sequence. It is worth highlighting that recycling incorporation waste carbonyl byproduct, generated in reduction step, into final compound realized. In addition, overall efficiency atom economy process are further improved owing to participation one reaction intermediate reductant allows lowering amount external reducing agent employed.

Language: Английский

Citations

4
CuH-Catalyzed Reductive Coupling of Nitroarenes with Phosphine Oxides for the Direct Synthesis of Phosphamides DOI

Jie Tang,

Zhiyou Li, Qi Meng

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(11), P. 7848 - 7858

Published: May 29, 2024

A CuH-catalyzed reductive coupling of nitroarenes with phosphine oxides is developed, which produces a series phosphamides in moderate to excellent yields good functional group tolerance. Gram-scale synthesis and late-stage modification nitro-aromatic molecule niclosamide are also successfully conducted. The mechanism study shows that the nitro transformed after being reduced nitroso nucleophilic addition procedure involved during reaction.

Language: Английский

Citations

4
Sulfonylation of Pyridyl Phosphonium Salts with Sulfinate Salts in Aqueous Media for the Synthesis of 4-Pyridyl Sulfones via C–P Bond Cleavage DOI

Bo‐Jie Huo,

Wenwen Wang, Yijie Huang

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 30, 2024

A Na

Language: Английский

Citations

4
Magnesium-Mediated Three-Component Reductive Cross-Couplings of Aryl Aldehydes, Aryl Bromides, and Aryl 2-Pyridyl Esters: An Efficient Synthesis of Diarylmethanol Esters DOI
Xiaowei Han,

Yuan-Shuai Wu,

Tie Wu

et al.

Tetrahedron, Journal Year: 2025, Volume and Issue: unknown, P. 134558 - 134558

Published: Feb. 1, 2025

Language: Английский

Citations

0
Synthesis of amides via TBN-induced oxidation cross-coupling of acetonitrile and N -sulfinylanilines DOI

Quansen Wu,

Zhuang Ma, Rui Li

et al.

Synthetic Communications, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 9

Published: April 21, 2025

Language: Английский

Citations

0