Oxyphosphorodithiolation of Vinyl Azides with P4S10 and Alcohols Leading to β-Keto Phosphorodithioates DOI

Jian Huang,

Chao Ma, Jian Sun

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(24), P. 18384 - 18392

Published: Dec. 10, 2024

A simple strategy for the synthesis of β-keto phosphorodithioates has been developed through direct oxyphosphorodithiolation vinyl azides with P

Language: Английский

Copper-catalysed radical cascade reaction of N-(2-oxo-2-phenylethyl) substituted 2-pyridones with styrene to access 1,6-carboannulated 2-pyridone scaffolds DOI

Shengkui Jin,

Liqiang Hao,

Cunneng Li

et al.

Organic & Biomolecular Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Herin, we present a DTBP-mediated 3 + 2 cycloaddition reaction between N -(2-oxo-2-phenylethyl) substituted 2-pyridones and styrene; this can afford 1,6-carboannulated 2-pyridone scaffolds with up to 79% yields.

Language: Английский

Citations

0
Condensation of carboxylic acids with amines using the Boc2O/DMAP system under solvent-free conditions DOI
Mourad Boukachabia, Mounia Merabet‐Khelassi, Olivier Riant

et al.

Organic & Biomolecular Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

We have developed an efficient solvent-free protocol for amide bond formation using Boc 2 O/DMAP, involving the in situ generation of a mixed anhydride and proceeding via sequential mechanism.

Language: Английский

Citations

0
Radical-mediated sulfonylation relay of alkyl alkynes/alkenes and electron-deficient alkenes to access vinyl and alkyl sulfones DOI
Jinhui Liu,

Fang Long,

Qing Li

et al.

Organic Chemistry Frontiers, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

A radical-mediated sulfonylation relay of alkyl alkynes/alkenes with electron-deficient alkenes using Na 2 S O 4 as a linker is developed to synthesize highly selective ( Z )-vinyl and sulfones under metal-free catalyzed system.

Language: Английский

Citations

0
Photoinduced Palladium-Catalyzed Radical Heck-Type Coupling of Cyclobutanone Oxime Esters with Vinyl Arenes DOI
Sen Yang,

Shasha Cai,

Junhua Li

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(10), P. 7243 - 7254

Published: May 2, 2024

A palladium-catalyzed radical Heck-type coupling reaction of cyclobutanone oxime esters with olefins under visible-light irradiation has been developed. The cyanoalkyl/Pd(I) hybrid species generated by selected ring-opening C–C bond cleavage imino/Pd(I) reacted smoothly vinyl arenes, delivering the cyanoalkylation mild conditions. This elegant strategy a broad scope and functional group tolerance. Subsequently, late-stage functionalization bioactive molecules synthetic transformations product further confirm practicality.

Language: Английский

Citations

2
Recent advances in radical cascade reaction for constructing nitrogen heterocycles using azides as radical acceptors DOI

Dong Xia,

Shi Yun,

Liying Jiang

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: 22(27), P. 5511 - 5523

Published: Jan. 1, 2024

The research advances in radical tandem cyclization for constructing nitrogen heterocycles which azide functions as a acceptor are reviewed.

Language: Английский

Citations

1
Iron-Catalyzed Perfluoroalkylarylation of Styrenes with Arenes and Alkyl Iodides Enabled by Halogen Atom Transfer DOI

Hanqing Zhao,

Wanting Li,

Yong Yao

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 18, 2024

A new iron-catalyzed three-component perfluoroalkylarylation of styrenes with alkyl halides and arenes has been established. Alkyl undergo halogen atom transfer methyl radicals to form in reactions initiated by a combination

Language: Английский

Citations

1
Electrophotocatalytic Thiocyanation and Sulfonylation Cyclization of Unactivated Alkenes DOI
Yingchun Ma,

Ping Yu,

Ruoyu Qin

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 18, 2024

We report an electrophotocatalytic process that enables the thiocyanation and sulfonylation/cyclization of alkenes. It is applicable to a wide range unactivated alkenes, using inexpensive photocatalyst 2,4,6-triphenylpyrylium tetrafluoroborate (TPPT) produce diverse array heterocycles containing sulfonyl thiocyano groups with good functional group tolerance. The protocol operates under mild, chemical oxidant- transition-metal-free, broad scope substrates. Preliminary mechanistic studies suggest reaction involves combination electrolysis reductive quenching photocatalytic cycle TPPT.

Language: Английский

Citations

1
Na2CO3-Promoted Synthesis of Thiocarbamates from Isocyanates and Thiols under Mild Conditions DOI

Yingbin Gong,

Leilei Yan,

Zhiqiang Guo

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: 22(31), P. 6277 - 6281

Published: Jan. 1, 2024

A method for the synthesis of thiocarbamates catalyzed by Na 2 CO 3 from isocyanates and thiols was developed, possible mechanism proposed. This has advantages high yield, good tolerance, atom economy mild conditions.

Language: Английский

Citations

0
One-pot synthesis of functionalized dihydropyridin-2-ones via carbene-catalyzed base-controlled [3+3] annulation reaction DOI
Zhan‐Yong Wang,

Guoyang Ma,

Yaoyao Xu

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Herein, we have described a novel organocatalytic approach to access biologically important dihydropyridin-2-ones in one-pot way with generally high yields (up 99%) and excellent enantioselectivities 99% ee). This reaction proceeded

Language: Английский

Citations

0
Synthesis of benzosultams via Ag(I)-catalyzed alkylative cyclization of vinyl sulfonamides DOI

Raju Dupud,

Karthik Kumar Merugu,

R Remyachand

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

A simple methodology for the synthesis of benzo-fused-γ-sultams via decarboxylative alkylation and cyclization vinyl sulfonamides is described. Carboxylic acids with diverse structural features were employed as alkyl sources in this method.

Language: Английский

Citations

0