I2-Promoted oxidative annulation of three different amines to access diverse biheteroaryls DOI

Guangping Fan,

Penghui Cao,

Fang Bai

et al.

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 25, 2024

An I 2 -promoted oxidative annulation of three different amines enables the assembly nonsymmetrical 2,2′-biquinolines and related bis-azines through a [4π + 2σ] reaction.

Language: Английский

Cu-Catalyzed biheterocyclization along with sulfonyl remote migration: Access to Marinoquinoline alkaloids and 4-sulfonyl pyrrolo[2,3-c]quinolines DOI

Lianshun Zhang,

Lan Bao,

Ting Song

et al.

Chinese Chemical Letters, Journal Year: 2025, Volume and Issue: unknown, P. 110915 - 110915

Published: Feb. 1, 2025

Language: Английский

Citations

0
Unlocking Isonitrile Insertion with N-Centered Radicals: A General Synthetic Strategy toward Quinazolinone Alkaloids by Synergistic Photo/Copper Catalysis DOI
Xiao-Yu Guo, Hui Wang,

Zhongyan Hu

et al.

ACS Catalysis, Journal Year: 2025, Volume and Issue: unknown, P. 5307 - 5317

Published: March 16, 2025

Language: Английский

Citations

0
Fe-Catalyzed Radical Trifluoromethylation and Cyclization of Ortho-Vinyl Enaminones with 1-(Trifluoromethyl)-1,3-benzo-[d][1,2]iodaoxol-3(1H)-one to Construct Functionalized Quinolines DOI

Qin Luo,

Z.‐F. XIE,

Cen Jian

et al.

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: May 19, 2025

Herein, we present a protocol for the construction of functionalized quinolines, i.e., 3-acyl-4-(2,2,2-trifluoro-ethyl)quinolines (ATFQLs) 4, from ortho-vinyl enaminones and 1-(trifluoromethyl)-1,3-benzo-[d][1,2]-iodaoxol-3(1H)-one, which was catalyzed by FeCp2 promoted FeCl3 (Lewis acid) additives in solvents (i.e., acetonitrile toluene). This strategy first utilized FeCp2-catalyzed functionalization alkenes with trifluoromethyl radicals. The intermediate formed captured ortho-iodobenzoate substrate, yielding 3, then underwent FeCl3-catalyzed elimination at higher temperature to form an α,β-unsaturated intermediate. subsequent intramolecular Michael reaction yielded final target compound 4. In summary, series ATFQLs 4 were synthesized through formation two bonds (C═C C-C).

Language: Английский

Citations

0
I2-Promoted oxidative annulation of three different amines to access diverse biheteroaryls DOI

Guangping Fan,

Penghui Cao,

Fang Bai

et al.

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 25, 2024

An I 2 -promoted oxidative annulation of three different amines enables the assembly nonsymmetrical 2,2′-biquinolines and related bis-azines through a [4π + 2σ] reaction.

Language: Английский

Citations

0