Asymmetric catalytic concise synthesis of 3-(3-indolomethyl)-oxindoles for the construction of trigolute analogs DOI

Zun Yang,

Zheng Jiang, Zheng Tan

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: 60(78), P. 10926 - 10929

Published: Jan. 1, 2024

In this paper, a newly asymmetric catalytic construction of 3-(3-indolomethyl)oxindoles was developed. Taking use method as the key step, concise syntheses trigolute analogs accomplished.

Language: Английский

Asymmetric Catalytic (3 + 2) Cyclization and Sequential Reaction to Construct Dihydrofuran- and Azepine-Based Spirooxindoles DOI

Qiliang Luo,

Yuqiao Zhou, Jing Zhang

et al.

Organic Letters, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 22, 2025

The enantioselective formal (3 + 2) cyclization and sequential reaction of 2-malononitrile-substituted oxindoles with benzaldehydes ortho-aminobenzaldehydes were achieved by chiral N,N′-dioxide/metal complex Lewis acid catalysts. This protocol supplies facile efficient access to highly functionalized dihydrofuran- azepine-based spirooxindoles. Based on the control experiments deuterium labeling studies, interconversion diastereomeric intermediates under conditions reversible 1,5-H transfer step disclosed.

Language: Английский

Citations

0
Catalytic Enantioselective Functionalization of Maleimides: An Update DOI Creative Commons
Muriel Amatore, Damien Bonne,

Thierry Constantieux

et al.

Chinese Journal of Chemistry, Journal Year: 2024, Volume and Issue: 42(24), P. 3605 - 3622

Published: Nov. 13, 2024

Comprehensive Summary Maleimide derivatives are well‐established reactive intermediates also found in natural products, synthetic pharmaceuticals and functional polymers. Their specific reactivity widespread applications the field of bioconjugation allowed for development highly selective functionalizations based on simple additions cycloadditions with possible control central C–N axial chirality. These multisite‐reactive scaffolds have aroused a long‐standing interest throughout scientific community more particularly as powerful electrophilic partners recently nucleophilic some transformations. The persistent these easily accessible platforms over last decade has enabled new enantioselective transformations major advancements this presented review. Key Scientists

Language: Английский

Citations

2
Asymmetric catalytic concise synthesis of 3-(3-indolomethyl)-oxindoles for the construction of trigolute analogs DOI

Zun Yang,

Zheng Jiang, Zheng Tan

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: 60(78), P. 10926 - 10929

Published: Jan. 1, 2024

In this paper, a newly asymmetric catalytic construction of 3-(3-indolomethyl)oxindoles was developed. Taking use method as the key step, concise syntheses trigolute analogs accomplished.

Language: Английский

Citations

1