Palladium-catalyzed N-arylation of (hetero)aryl chlorides with pyrroles and their analogues DOI

Ying Yin,

Yuxuan Xiao,

Xun Yang

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 26, 2024

A practical method for N -arylation of N–H heteroarenes with aryl chlorides through Pd/keYPhos catalyzed selective cleavage the Ar–Cl bond under mild conditions has been developed.

Language: Английский

Transformative Reactions in Nitroarene Chemistry: Advances in C–N Bond Cleavage, Skeletal Editing, and N–O Bond Utilization DOI Creative Commons

Keiichiro Iizumi,

Junichiro Yamaguchi

Organic & Biomolecular Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

This review aims to provide a comprehensive overview of the expanding utility nitroarenes and their potential for future applications in synthetic organic chemistry.

Language: Английский

Citations

1
Denitrative Functionalization of Nitroarenes: Recent Progress and Future Perspectives DOI
Haiyan Li,

Zhiguo Lei,

Xun Yang

et al.

European Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 27(45)

Published: Aug. 27, 2024

Abstract Nitroarenes are fundamental feedstocks in the chemical industry. Their relatively inert C−NO 2 bond allows for late‐stage modifications of molecules and exhibits complete orthogonality to reactivity C‐halogen cross‐coupling reactions. The denitrative functionalization nitroarenes holds significant appeal due it avoids use aryl halides, thereby simplifying reaction steps improving atom step economy. Recent progress direct includes palladium‐catalyzed coupling, copper‐catalyzed as well metal‐free one‐pot functionalization. In this review, we provide a concise overview these advancements, detailing features mechanisms. This summary aims highlight versatility efficiency methodologies, offering insights into their potential applications inspiring further research promising area organic synthesis.

Language: Английский

Citations

3
Palladium-catalyzed carbon–carbon bond cleavage of primary alcohols: decarbonylative coupling of acetylenic aldehydes with haloarenes DOI Creative Commons

Zewei Jin,

Qiang Li, Maoshuai Zhu

et al.

RSC Advances, Journal Year: 2025, Volume and Issue: 15(10), P. 7826 - 7831

Published: Jan. 1, 2025

We report a novel method for the palladium-catalyzed cleavage of C–C bonds in primary alcohols, thereby enabling new route synthesis diarylacetylenes.

Language: Английский

Citations

0
Palladium-Catalyzed Coupling of Aryl Chlorides with Secondary Phosphines to Construct Unsymmetrical Tertiary Phosphines DOI
Yuxuan Xiao, Xun Yang, Haiyan Li

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 29, 2024

The functionalization of the C-Cl bond in unactivated aryl chlorides under mild conditions presents a significant challenge. We disclose general protocol for constructing both partially and entirely unsymmetrical tertiary phosphines through Pd/keYPhos-catalyzed coupling with secondary conditions. reaction exhibits excellent functional group tolerance broad substrate scopes. Furthermore, rapid synthesis ligands luminescent compound sTPPs, alongside gram-scale systhesis, demonstrates practical applicability this method.

Language: Английский

Citations

2
Transition-metal-free Photochemical Reductive Denitration of Nitroarenes DOI
Shuai Tang, Weidong Xu, Hua Zhang

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: 60(93), P. 13754 - 13757

Published: Jan. 1, 2024

A mild, transition-metal-free photochemical process for reductive denitration of nitroarenes with broad functional group compatibility has been developed.

Language: Английский

Citations

0
Palladium-catalyzed N-arylation of (hetero)aryl chlorides with pyrroles and their analogues DOI

Ying Yin,

Yuxuan Xiao,

Xun Yang

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 26, 2024

A practical method for N -arylation of N–H heteroarenes with aryl chlorides through Pd/keYPhos catalyzed selective cleavage the Ar–Cl bond under mild conditions has been developed.

Language: Английский

Citations

0