Organic Letters, Journal Year: 2025, Volume and Issue: unknown
Published: March 25, 2025
A new catalytic conversion type of nitro substrate with CO2 as a single-carbon source is presented, wherein great collection azaheterocycles generated by newly established iridium-catalyzed, copper-induced reductive system. This procedure handily employs poly(methylhydrosiloxane) (PMHS) the reductant to simultaneously realize dual reduction highest oxidation-state and units in one operation. Elaborate mechanistic studies illustrate essential role iridium catalyst reducing NO2 moiety well double functions copper additive subsequent formylation C-H cyclization steps.
Language: Английский