Frontiers in Chemistry,
Journal Year:
2020,
Volume and Issue:
8
Published: June 12, 2020
An
iodine/DMSO
catalyzed
selective
cyclization
of
N-tosylhydrazones
with
sulfur
without
adding
external
oxidant
was
developed
for
the
synthesis
4-aryl-1,2,3-thiadiazoles.
In
this
reaction,
oxidation
HI
by
using
DMSO
as
dual
and
solvent
is
key,
which
allowed
regeneration
I2,
ensuring
thus
success
synthesis.
This
protocol
features
simple
operation,
high
step-economy
(one-pot
fashion),
broad
substrate
scope
well
scale-up
ability.
ACS Sustainable Chemistry & Engineering,
Journal Year:
2019,
Volume and Issue:
7(7), P. 7193 - 7199
Published: March 8, 2019
An
environmentally-friendly
method
for
the
clean
preparation
of
various
quinolin-2-yl
substituted
ureas
in
water
under
mild
and
toxic
reagent-,
base-,
organic
solvent-free
conditions
was
established.
In
large-scale
synthesis,
products
could
be
rapidly
collected
via
simple
filtration
washing
with
ethanol.
The
usage
readily
available
raw
materials,
100%
atom
economy,
high
yield,
excellent
regioselectivity
enhanced
practicability
this
protocol.
Organic Chemistry Frontiers,
Journal Year:
2021,
Volume and Issue:
8(11), P. 2710 - 2771
Published: Jan. 1, 2021
This
review
presents
a
critical
and
authoritative
analysis
of
several
exciting
benzannulation
approaches
developed
in
the
past
decade
for
construction
carbazoles,
indolocarbazoles,
benzocarbazoles,
carbolines.
Green Chemistry,
Journal Year:
2019,
Volume and Issue:
22(1), P. 118 - 122
Published: Nov. 29, 2019
A
practical
method
for
the
clean
preparation
of
multisubstituted
pyrroles
via
an
iodine-catalyzed
multicomponent
reaction
under
metal-
and
solvent-free
conditions
was
developed.
In
gram-scale
synthesis,
can
be
easily
collected
through
simple
extraction.
Organic Letters,
Journal Year:
2019,
Volume and Issue:
21(9), P. 3372 - 3376
Published: April 23, 2019
A
new,
one-pot
domino
benzannulation
reaction
between
indole-3-ynones
and
various
nitromethane
derivatives
has
been
explored
for
a
general
entry
to
diversely
functionalized
carbazole
frameworks
(28
examples).
The
scope
of
this
new
extended
variants
like
2-chloroindole-3-ynones
eventuate
in
chemo-differentiated
1,2,3,4-tetrasubstituted
carbazoles
with
retention
the
nitro
group.
efficacy
strategy
demonstrated
through
concise
total
synthesis
natural
products,
viz.
carbazomycin
A,
calothrixin
B,
staurosporinone
(K252c).
Organic Letters,
Journal Year:
2021,
Volume and Issue:
23(11), P. 4406 - 4410
Published: May 21, 2021
A
novel
Rh(III)-catalyzed
C–H
activation/annulation
cascade
of
indole-enaminones
with
diazo
compounds
was
reported
to
construct
diversely
functionalized
carbazole
frameworks.
The
most
notable
characteristic
is
that
this
transformation
could
smoothly
furnish
a
[5
+
1]
cyclization
product
good
excellent
yields
(up
95%),
accompanied
by
the
thorough
removal
acetyl
and
N,N-dimethyl
groups
two
substrates
from
target
products,
rather
than
normally
expected
[4
2]
products.
