Bioprinting, Journal Year: 2024, Volume and Issue: unknown, P. e00379 - e00379
Published: Dec. 1, 2024
Language: Английский
Materials Today Bio, Journal Year: 2025, Volume and Issue: 31, P. 101531 - 101531
Published: Feb. 5, 2025
Three-dimensional (3D) printing technology has shown significant promise in the medical field, particularly orthopedics, prosthetics, tissue engineering, and pharmaceutical preparations. This review focuses on innovative application of 3D addressing challenges osteonecrosis femoral head (ONFH). Unlike traditional hip replacement surgery, which is often suboptimal for younger patients, offers precise localization necrotic areas ability to create personalized implants. By integrating advanced biomaterials, this a promising strategy approach early hip-preserving treatments. Additionally, 3D-printed bone engineering scaffolds can mimic natural environment, promoting regeneration vascularization. In future, potential extends combining with artificial intelligence optimizing treatment plans, developing materials enhanced bioactivity compatibility, translating these innovations from laboratory clinical practice. demonstrates how uniquely addresses critical ONFH treatment, including insufficient vascularization, poor mechanical stability, limited long-term success conventional therapies. introducing gradient porous scaffolds, bioactive material coatings, AI-assisted design, work outlines novel strategies improve interventions. These advancements not only enhance efficacy but also pave way findings into applications.
Language: Английский
Citations
1
Biofabrication, Journal Year: 2025, Volume and Issue: 17(2), P. 022005 - 022005
Published: Jan. 31, 2025
Gradient tissues are anisotropic structure with gradual transition in structural and biological properties. The gradient structural, mechanical biochemical properties of osteochondral meniscal play a major role defining tissue functions. Designing substitutes that replicate these is crucial to facilitate regeneration functions following injuries. Advanced manufacturing technologies such as 3D bioprinting hold great potentials for recreating nature through using zone-specific bioinks layer-by-layer deposition spatially defined biomaterials, cell types bioactive cues. This review highlighted the gradients detail, elaborated on individual components bioink, reviewed recent advancements gradient-based substitutes. Finally, key challenges field future perspectives developing were discussed. insights from advances can broaden possibilities engineering tissues.
Language: Английский
Citations
0
Current Treatment Options in Cardiovascular Medicine, Journal Year: 2025, Volume and Issue: 27(1)
Published: Jan. 31, 2025
Language: Английский
Citations
0
Bioprinting, Journal Year: 2024, Volume and Issue: unknown, P. e00365 - e00365
Published: Oct. 1, 2024
Language: Английский
Citations
3
BioNanoScience, Journal Year: 2024, Volume and Issue: 15(1)
Published: Dec. 17, 2024
Language: Английский
Citations
2
Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 17, 2024
Abstract Regeneration of oral soft tissue defects, including mucogingival defects associated with the recession or loss gingival and/or mucosal tissues around teeth and implants, is crucial for restoring form, function, health. This study presents a novel approach using three‐dimensional (3D) bioprinting to fabricate individualized grafts precise size, shape, layer‐by‐layer cellular organization. A multicomponent polysaccharide/fibrinogen‐based bioink developed, parameters are optimized create shape‐controlled (gingival) constructs. Rheological, printability, shape‐fidelity assays, demonstrated influence thickener concentration print on resolution shape fidelity. Artificial intelligence (AI)‐derived tool enabled streamline iterative parameter optimization analysis interaction between parameters. The cell‐laden bioinks exhibited excellent viability fidelity shape‐controlled, full‐thickness constructs over 18‐day culture period. While variations in concentrations within minimally impact organization morphogenesis (gingival epithelial, connective tissue, basement membrane markers), they bioprinted represents significant step toward biofabrication personalized grafts, offering potential applications repair regeneration periodontal disease dental implants.
Language: Английский
Citations
2
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 280, P. 135999 - 135999
Published: Sept. 24, 2024
Language: Английский
Citations
1
Biomedical Materials, Journal Year: 2024, Volume and Issue: 20(1), P. 012004 - 012004
Published: Dec. 20, 2024
Bioprinting has the potential to revolutionize tissue engineering and regenerative medicine, offering innovative solutions for complex medical challenges addressing unmet clinical needs. However, traditional
Language: Английский
Citations
1
Bioprinting, Journal Year: 2024, Volume and Issue: unknown, P. e00379 - e00379
Published: Dec. 1, 2024
Language: Английский
Citations
0