ACS Applied Optical Materials,
Journal Year:
2024,
Volume and Issue:
2(4), P. 595 - 603
Published: March 25, 2024
Alloyed
upconversion
nanoparticles
(aUCNPs,
NaYbF4:10%
Er@NaYF4)
with
high
Yb3+
doping
were
designed
to
brighten
luminescence,
exploring
multicolor
patterns
of
information
encryption.
The
luminescence
intensity
aUCNPs
was
2.3
times
higher
than
that
common
doped
UCNPs
reported
(dUCNPs,
NaYF4:20%
Yb,
2%
Er@NaYF4).
Furthermore,
because
the
(90%),
both
green
and
red
emissions
enhanced,
∼4.2
∼17.2
stronger
10%
Er@NaYF4,
respectively.
reasons
for
having
a
brightened
explored
by
synthesizing
four
different
structures
comparing
their
luminescence.
These
are
attributed
unique
features:
(1)
larger
absorption
cross
section
accumulating
energy,
(2)
more
efficient
energy
transfer
between
Er3+,
(3)
inert
shell
inhibiting
surface
quenching.
Eventually,
three
colors
including
yellow,
orange,
obtained
combining
neutral
(NR)
taking
advantage
inner
filter
effect
(IFE),
thus
successfully
applied
in
encryption
patterns.
Advanced Functional Materials,
Journal Year:
2024,
Volume and Issue:
34(19)
Published: Jan. 4, 2024
Abstract
The
blood–brain
barrier
(BBB)
is
a
tailored
system
of
capillary
endothelial
cells
intermixed
with
tight
junctions
and
adherent
that
regulates
the
transport
various
materials
substances
between
blood
vasculature
central
nervous
(CNS).
However,
in
cases
brain
diseases,
BBB's
protective
regulatory
effects
hamper
therapeutics
from
reaching
affected
sites
sufficient
quantities.
This
has
so
far
been
leading
challenge
treating
CNS
diseases
disorders.
For
this
problem
to
be
overcome,
recent
research
sought
develop
novel
modalities
achieve
efficient
therapy
alleviate
associated
symptoms.
Therefore,
numerous
strategies
have
operated
years
address
limitations
traditional
invasive
methods,
including
poor
penetration
serious
side
effects.
As
desperately
in‐demand
technology,
nanotheranostics
particularly
shown
promising
results.
Herein,
review
reports
advancements
techniques
nanotechnology‐based
developed
for
neurodegenerative
study
provides
comprehensive
data
on
subject
used
future
studies
management
disorders
diseases.
Chemistry of Materials,
Journal Year:
2024,
Volume and Issue:
36(9), P. 4054 - 4077
Published: April 18, 2024
Stimuli-responsive
self-immolative
polymers
(SIPs)
represent
a
unique
class
of
that
can
undergo
controlled,
sequential
head-to-tail
depolymerization
upon
specific
stimuli.
Since
their
inception,
they
have
evolved
over
two
decades
to
become
one
the
most
attractive
polymer
types.
With
characteristic
feature
"one
stimulus,
multiple
responses",
SIPs
inherently
possess
ability
serve
as
chemical
amplifiers,
which
amplify
weak
or
biological
signals.
This
promises
higher
stimulus
sensitivity,
greater
selectivity
for
microenvironments,
and
potential
generate
more
persistent,
extensive,
significant
responses
while
consuming
fewer
stimuli
sources.
Review
summarizes
latest
research
advancements
in
stimuli-responsive
drug
delivery
molecular
imaging
past
five
years.
Regarding
structure
SIPs,
we
briefly
overview
updates
self-immolation
units,
end-cap
moieties,
sequence
SIPs.
In
terms
applications,
focus
on
possible
applications
disease
treatment
methods.
Finally,
provide
brief
perspective
future
directions
these
applications.
Materials Today Bio,
Journal Year:
2025,
Volume and Issue:
31, P. 101470 - 101470
Published: Jan. 9, 2025
Pseudomonas
aeruginosa
infection
is
the
most
common
pathogen
in
burn
wound
infections,
causing
delayed
healing
and
progression
to
chronic
wounds.
Therefore,
there
an
urgent
need
develop
antimicrobial
agents
that
can
promote
for
effectively
treating
infected
Using
magnetic
stirring
ultrasound
synthesize
Apt-pM@UCNPmSiO2-Cur-CAZ.
The
nanosystems
were
characterized
using
transmission
electron
microscopy
(TEM),
dynamic
light
scattering
(DLS),
ultraviolet-visible
spectrophotometry
(UV-Vis).
Flow
cytometry,
bacterial
LIVE/DEAD
staining
scanning
performed
assess
vitro
antibacterial
anti-biofilm
effects
of
nanosystems.
potential
vivo
toxicity
evaluated
a
mouse
skin
model.
Apt-pM@UCNPmSiO2-Cur-CAZ
synthesized
exhibited
uniform
circular
shape
with
Zeta
-0.8
mV.
In
vitro,
demonstrated
superior
compared
standalone
antibiotics.
Bacteria
treated
showed
varying
degrees
deformation
shrinkage,
resulting
severe
damage
cells.
Additionally,
inhibit
eradicate
biofilms,
while
also
targeting
bacteria
enhanced
efficacy.
Interestingly,
NIR
could
enhance
due
photodynamic
action.
model,
nanosystem
eliminated
bacteria,
promoting
aeruginosa-infected
wounds
without
significant
toxic
effects.
novel
targeted
nano-delivery
system
promising
combating
it
may
serve
as
new
therapeutic
approach
infections.
Lanthanide-doped
upconversion
luminescent
nanoparticles
(UCNPs)
have
garnered
extensive
attention
due
to
their
notable
anti-Stokes
shifts
and
superior
photostability.
Notably,
Ho3+-based
UCNPs
present
a
complex
energy
level
configuration,
which
poses
challenges
in
augmenting
luminescence
efficiency.
Herein,
rational
design
strategy
was
used
enhance
the
intensity
of
Ho3+
ions
by
improving
photon
absorption
ability
utilization
Efficient
transfer
excitation
light
were
achieved
through
carefully
selected
host
materials,
precisely
controlled
sensitizers,
external
antennas
using
organic
dyes,
enhancing
luminescence.
Due
attenuation
effect
hydroxyl
vibration
on
luminescence,
nanomaterials
exhibit
multicolor
characteristics
different
solution
environments.
Significantly,
composites
intense
red
aqueous
solution,
showing
great
application
potential
biomedicine
colorimetry.
