
Vaccine, Journal Year: 2024, Volume and Issue: 45, P. 126648 - 126648
Published: Dec. 20, 2024
Language: Английский
Vaccine, Journal Year: 2024, Volume and Issue: 45, P. 126648 - 126648
Published: Dec. 20, 2024
Language: Английский
Drug Delivery and Translational Research, Journal Year: 2025, Volume and Issue: unknown
Published: April 16, 2025
Language: Английский
Citations
1Colloids and Surfaces B Biointerfaces, Journal Year: 2024, Volume and Issue: 248, P. 114478 - 114478
Published: Dec. 28, 2024
Language: Английский
Citations
4Nanoscale, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 31, 2024
Gold nanorods (AuNRs) have shown great potential as photothermal agents for cancer therapy. However, the biosafety of AuNRs ordinarily synthesized using a cationic ligand assistance procedure has always been subject controversy, which limits their application in tumor In this study, we propose novel strategy to enhance biocompatibility by constructing biological coating derived from silk fibroin (SF) on surface. The SF could be easily and precisely manipulated layer-by-layer (LBL) assembly method. resulting SF-coated gold (AuNRs@SF) exhibited reduced cytotoxicity improved hemocompatibility compared untreated AuNRs. Moreover, treated were modified with tumor-targeting peptide (AuNRs@MTSF) efficiently loaded indocyanine green (ICG). Both vitro vivo analyses demonstrated that AuNRs@MTSF more effectively reach tissue enter MCF-7 cells. Furthermore, after loading ICG, superior antitumor efficacy other groups combining photodynamic therapy (PDT) (PTT) under near-infrared (NIR) irradiation without inducing any side effects. This work suggests is approach improving biocompatibility, function-modified AuNRs@SF are effective nanoplatforms targeted multimodal
Language: Английский
Citations
2Vaccine, Journal Year: 2024, Volume and Issue: 45, P. 126648 - 126648
Published: Dec. 20, 2024
Language: Английский
Citations
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