Multifunctional Gemini Surfactants: Structure, Synthesis, Properties and Applications DOI Open Access
Bogumił Brycki, Iwona Kowalczyk,

Adrianna Szulc

et al.

InTech eBooks, Journal Year: 2017, Volume and Issue: unknown

Published: July 5, 2017

Gemini cationic surfactants are compounds which composed of two hydrophilic head groups and hydrophobic tails linked by a spacer at the or closed to them. The can be either hydrophilic. It rigid flexible. neutral charge molecule is retained presence organic inorganic counterions. Critical micelle concentrations (CMCs), surface tension (γ) minimal inhibitory concentration (MIC) dozen times lower than corresponding parameters monomeric surfactants. unique properties gemini with wide range hydrophilic-lipophilic balance (HLB) make them very useful, innovative material in detergents, cosmetics, personal care products, additives for paints coatings, biocides, science, synthesis, pharmacy, textiles, enhanced oil recovery, nanotechnology, petroleum many other branches life. A large number papers concerning have been published so far. This review presents synthetic look current work devoted structure, synthesis applications

Language: Английский

Surface Design for Antibacterial Materials: From Fundamentals to Advanced Strategies DOI Creative Commons
Wenlong Li, Eng San Thian, Miao Wang

et al.

Advanced Science, Journal Year: 2021, Volume and Issue: 8(19)

Published: Aug. 5, 2021

Healthcare-acquired infections as well increasing antimicrobial resistance have become an urgent global challenge, thus smart alternative solutions are needed to tackle bacterial infections. Antibacterial materials in biomedical applications and hospital hygiene attracted great interest, particular, the emergence of surface design strategies offer effective antibiotics, thereby preventing possible development resistance. In this review, recent progress on advanced modifications prevent addressed comprehensively, starting with key factors against adhesion, followed by varying that can inhibit biofilm formation effectively. Furthermore, "super antibacterial systems" through pre-treatment defense targeted bactericidal system, proposed evidence clinical potential. Finally, advantages future challenges resist healthcare-associated discussed, promising prospects developing novel materials.

Language: Английский

Citations

294

Silver nanoparticle-embedded hydrogel as a photothermal platform for combating bacterial infections DOI
Yingnan Liu, Li Fan, Zhirong Guo

et al.

Chemical Engineering Journal, Journal Year: 2019, Volume and Issue: 382, P. 122990 - 122990

Published: Sept. 27, 2019

Language: Английский

Citations

238

Antimicrobial Ionic Liquid‐Based Materials for Biomedical Applications DOI Creative Commons
Nasser Nikfarjam, Matineh Ghomi, Tarun Agarwal

et al.

Advanced Functional Materials, Journal Year: 2021, Volume and Issue: 31(42)

Published: July 23, 2021

Abstract Excessive and unwarranted administration of antibiotics has invigorated the evolution multidrug‐resistant microbes. There is, therefore, an urgent need for advanced active compounds. Ionic liquids with short‐lived ion‐pair structures are highly tunable have diverse applications. Apart from their unique physicochemical features, newly discovered biological activities ionic fascinated biochemists, microbiologists, medical scientists. In particular, antimicrobial properties opened new vistas in overcoming current challenges associated combating antibiotic‐resistant pathogens. Discussions regarding liquid derivatives monomeric polymeric forms presented here. The mechanism parameters that affect activities, such as chain length, cation/anion type, cation density, polymerization, considered. potential applications biomedical arena, including regenerative medicine, biosensing, drug/biomolecule delivery, to stimulate scientific community further improve efficacy liquids.

Language: Английский

Citations

219

Porphyrin MOF Dots–Based, Function‐Adaptive Nanoplatform for Enhanced Penetration and Photodynamic Eradication of Bacterial Biofilms DOI
Qingqing Deng, Panpan Sun, Lu Zhang

et al.

Advanced Functional Materials, Journal Year: 2019, Volume and Issue: 29(30)

Published: June 4, 2019

Abstract Recently, antimicrobial photodynamic therapy (aPDT) has been considered as an attractive treatment option for biofilms ablation. However, even very efficient photosensitizers (PSs) still need high light doses and PS concentrations to eliminate due the limited penetration diffusion of PSs in biofilms. Moreover, hypoxic microenvironment rapid depletion oxygen during PDT severely limit their therapeutic effects. Herein, first time, a porphyrin‐based metal organic framework (pMOF) dots–based nanoplatform with effective biofilm penetration, self‐oxygen generation, enhanced efficiency is synthesized bacterial eradication. The function‐adaptive composed pMOF dots encapsulated by human serum albumin–coated manganese dioxide (MnO 2 ). pH/H O ‐responsive decomposition MnO triggers release ultra‐small positively charged simultaneously generates situ alleviate hypoxia released reactive species yield can effectively penetrate into biofilms, strongly bind cell surface, ablate Importantly, such realize great outcomes Staphylococcus aureus –infected subcutaneous abscesses vivo without damage healthy tissues, which offers promising strategy

Language: Английский

Citations

217

Structure–activity relationship of cationic surfactants as antimicrobial agents DOI
Chengcheng Zhou, Yilin Wang

Current Opinion in Colloid & Interface Science, Journal Year: 2019, Volume and Issue: 45, P. 28 - 43

Published: Dec. 6, 2019

Language: Английский

Citations

183

Ionic Liquid‐Based Polymer Nanocomposites for Sensors, Energy, Biomedicine, and Environmental Applications: Roadmap to the Future DOI Creative Commons
Kirti Bhushan Mishra, Nishu Devi, Samarjeet Singh Siwal

et al.

Advanced Science, Journal Year: 2022, Volume and Issue: 9(26)

Published: July 19, 2022

Current interest toward ionic liquids (ILs) stems from some of their novel characteristics, like low vapor pressure, thermal stability, and nonflammability, integrated through high conductivity broad range electrochemical strength. Nowadays, represent a new category chemical-based compounds for developing superior multifunctional substances with potential in several fields. ILs can be used solvents such as salt electrolyte additional materials. By adding functional physiochemical variety IL-based electrolytes also energy storage purposes. It is hoped that the present review will supply guidance future research focused on polymer nanocomposites sensors, performance, biomedicine, environmental applications. Additionally, comprehensive overview about polymer-based composites' components, including classification types matrix available provided this review. More focus placed upon ILs-based polymeric multiple applications biosensors, energy-related materials, actuators, environmental, aviation aerospace industries. At last, existing challenges prospects field are discussed concluding remarks provided.

Language: Английский

Citations

116

Antimicrobial activity of quaternary ammonium salts: structure-activity relationship DOI Open Access
Mallikarjuna N. Nadagouda,

Pooja Vijayasarathy,

Aebin Sin

et al.

Medicinal Chemistry Research, Journal Year: 2022, Volume and Issue: 31(10), P. 1663 - 1678

Published: July 2, 2022

Language: Английский

Citations

82

Synthesis of Cu-Nanoparticle Hydrogel with Self-Healing and Photothermal Properties DOI
Shuai Chen, Fu Tang,

Liangzhen Tang

et al.

ACS Applied Materials & Interfaces, Journal Year: 2017, Volume and Issue: 9(24), P. 20895 - 20903

Published: June 1, 2017

Copper (Cu) nanoparticles possess unusual electrical, thermal, and optical properties. However, applications of these materials are often limited by their tendency to oxidize. We prepared Cu a simple polyol method, with good control over the particle size. The reaction required no inert atmosphere or surfactant agents. as-prepared showed resistance oxidation in solution. These were then incorporated into biocompatible polysaccharide hydrogel, which further stabilized nanoparticles. hybrid hydrogel exhibited rapid self-healing ability. Because excellent photothermal conversion properties embedded nanoparticles, temperature elevation under laser irradiation. cytotoxicity; however, irradiation displayed antibacterial owing heating effects. This study demonstrates that our may have biomedical fields therapy.

Language: Английский

Citations

162

The Impact of Biosurfactants on Microbial Cell Properties Leading to Hydrocarbon Bioavailability Increase DOI Creative Commons
Ewa Kaczorek, Amanda Pacholak, Agata Zdarta

et al.

Colloids and Interfaces, Journal Year: 2018, Volume and Issue: 2(3), P. 35 - 35

Published: Aug. 26, 2018

The environment pollution with hydrophobic hydrocarbons is a serious problem that requires development of efficient strategies would lead to bioremediation contaminated areas. One the common methods used for enhancement biodegradation pollutants addition biosurfactants. Several mechanisms have been postulated as responsible bioavailability They include solubilization and desorption well modification bacteria cell surface properties. presented review contains wide discussion these in context alteration efficiency It brings new light such complex important issue.

Language: Английский

Citations

149

Design, Synthesis, and Nanostructure-Dependent Antibacterial Activity of Cationic Peptide Amphiphiles DOI
Nathália Rodrigues de Almeida, Yuchun Han, J. Manuel Perez

et al.

ACS Applied Materials & Interfaces, Journal Year: 2018, Volume and Issue: 11(3), P. 2790 - 2801

Published: Dec. 27, 2018

The development of bacterial resistant strains is a global health concern. Designing antibiotics that limit the rise pathogenic resistance essential to efficiently treat infections. Self-assembling amphiphilic molecules are an intriguing platform for treatment pathogens because their ability disrupt membranes and function as drug nanocarriers. We have designed cationic peptide amphiphiles (PAs) can form micelles, nanofibers, twisted ribbons with aim understanding antimicrobial activity at supramolecular level. found micelle-forming PAs possess excellent against various Gram-positive Gram-negative pathogens, such methicillin-resistant Staphylococcus aureus (MRSA) multidrug-resistant Klebsiella pneumoniae minimal inhibitory concentrations (MICs) ranging between 1 8 μg/mL, when compared nanofibers MICs >32 μg/mL. data suggest depends on morphology, amino acid sequence, length alkyl tail, overall hydrophobicity PA. Scanning electron microscopy, confocal flow cytometry studies using MRSA Escherichia coli K12 showed increase cell membrane permeability integrity pathogen's membrane, leading lysis death. promising develop new antimicrobials could work nanocarriers synergistic antibacterial therapies.

Language: Английский

Citations

125