Biomedical SERS – the current state and future trends

Chemical Society Reviews, Journal Year: 2024, Volume and Issue: 53(18), P. 8957 - 8979

Published: Jan. 1, 2024

Surface enhanced Raman spectroscopy (SERS) is meeting the requirements in biomedical science being a highly sensitive and specific analytical tool. By employing portable systems combination with customized sample pre-treatment, point-of-care-testing (POCT) becomes feasible. Powerful SERS-active sensing surfaces high stability modification layers if required are available for testing application complex biological matrices such as body fluids, cells or tissues. This review summarizes current state collection pretreatment SERS detection protocols, schemes,

Language: Английский

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Biosafety aspects of RNAi‐based pests control

Pest Management Science, Journal Year: 2024, Volume and Issue: 80(8), P. 3697 - 3706

Published: March 23, 2024

Abstract While the overuse of classical chemical pesticides has had a detrimental impact on environment and human health, discovery RNA interference (RNAi) offered opportunity to develop new sustainable approaches for pest management. RNAi is naturally occurring regulation defense mechanism that can be exploited effectively protect crops by silencing key genes affecting growth, development, behavior or fecundity pests. However, as with all technologies, there range potential risks challenges associated application RNAi, such dsRNA stability, off‐target effects, safety non‐target organisms, other challenges. A better understanding molecular mechanisms involved in in‐depth discussion analysis these risks, required limit mitigate adverse effects. © 2024 Society Chemical Industry.

Language: Английский

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Interactions of foliar nanopesticides with insect cuticle facilitated through plant cuticle: Effects of surface chemistry and roughness-topography-texture

Plant Nano Biology, Journal Year: 2024, Volume and Issue: 7, P. 100062 - 100062

Published: Feb. 1, 2024

In response to the growing worldwide demand for enhanced agricultural output and sustainable farming practices, nanopesticides have become a significant area of investigation in research. Importantly, fate, distribution, efficacy any nanopesticide is linked interfacial attributes dynamic interactions between outer surfaces – cuticle plants insects. This review starts with an outline diverse pathways facilitating accumulation on plant cuticles, including their eventual transfer cuticles insect pests. Subsequently, comprehensive overview provided micro- nano-scale morphological features characteristic along implications these hold various nanopesticides. The then focuses mediated through cuticle. Finally, nanoscale mechanistic processes are discussed, emphasis aspects such as wetting dynamics, critical length scales (e.g., inter-crystal spacing waxes surface wavelengths), interdigitation molecular adhesion long-chain macromolecular nanocarriers. Collectively, elucidates essential governing entities. concluding section provides prevailing challenges potential avenues understanding transport deposition mechanisms

Language: Английский

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Sea urchin-like nanocarrier for enhancing pesticide retention and rain fastness on hydrophobic and hydrophilic crop foliage

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 490, P. 151901 - 151901

Published: May 6, 2024

Language: Английский

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Novel Environmentally Friendly RNAi Biopesticides: Targeting V-ATPase in Holotrichia parallela Larvae Using Layered Double Hydroxide Nanocomplexes

Journal of Agricultural and Food Chemistry, Journal Year: 2024, Volume and Issue: 72(20), P. 11381 - 11391

Published: May 10, 2024

RNA interference (RNAi)-based biopesticides offer an attractive avenue for pest control. Previous studies revealed high RNAi sensitivity in Holotrichia parallela larvae, showcasing its potential grub In this study, we aimed to develop environmentally friendly method H. larvae. The double-stranded (dsRNA) of the V-ATPase-a gene (HpVAA) was loaded onto layered double hydroxide (LDH). dsRNA/LDH nanocomplex exhibited increased environmental stability, and investigated absorption rate permeability dsRNA–nanoparticle complexes explored controlling effect. Silencing HpVAA found darken epidermis with growth cessation or death mortality, disrupting midgut structure. Quantitative reverse transcription-polymerase chain reaction confocal microscopy confirmed effective by peanut plants, distribution roots, stems, leaves. Nanomaterial-mediated silenced target genes, leading pests. Therefore, these findings indicate successful application nanomaterial-mediated system underground pests, thus establishing a theoretical foundation developing green, safe, efficient control strategy.

Language: Английский

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Perfect cooperative pest control via nano-pesticide and natural predator: High predation selectivity and negligible toxicity toward predatory stinkbug

Chemosphere, Journal Year: 2024, Volume and Issue: 355, P. 141784 - 141784

Published: March 25, 2024

Language: Английский

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Preparation of a Fluxapyroxad Nanoformulation with Strong Plant Uptake for Efficient Control of Verticillium Wilt in Potato

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 11, 2025

Potato (Solanum tuberosum L.) is ranked as the fourth largest staple crop in China. However, potato production increasingly threatened by Verticillium wilt (VW) caused fungus dahliae various provinces. In present study, we explored application of star polycation (SPc) nanocarrier to improve effectiveness fungicide fluxapyroxad (Flu) combating VW. The SPc self-assembled with Flu through hydrogen bonds and van der Waals forces form Flu/SPc complex spontaneously, which exhibited strong intermolecular interactions, indicated a high affinity constant favorable thermodynamic parameters. Complexation decreased particle size Flu. had greater effect on V. than alone, reducing colony diameter spore numbers more effectively. Expression levels multiple key genes involved nitrogen, polysaccharide, sugar metabolism were downregulated upon treatment compared treatment, might contribute growth inhibition Flu/SPc-treated samples. Uptake studies plants demonstrated that significantly enhanced absorption alone. Slighter disease symptoms lower fungal biomass greenhouse field trials confirmed protective effects seedlings. This first report nanofungicide limits protects potatoes from destructive

Language: Английский

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CYP321F3 mediates metabolic resistance to methoxyfenozide in rice stem borer, Chilo suppressalis

Pesticide Biochemistry and Physiology, Journal Year: 2025, Volume and Issue: unknown, P. 106383 - 106383

Published: March 1, 2025

Language: Английский

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Sustainable Nanomaterials: Principles and Practices

Sustainable development and biodiversity, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 27

Published: Jan. 1, 2025

Language: Английский

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Toxicity evaluation of metsulfuron-methyl, nicosulfuron, and methoxyfenozide as pesticides in Indonesia

Open Agriculture, Journal Year: 2025, Volume and Issue: 10(1)

Published: Jan. 1, 2025

Abstract Pesticides are substances widely used to control or eliminate pests, including weeds, insects, and other harmful organisms. Agricultural pesticides, in particular, must meet specific safety quality standards before being marketed. In this study, the acute chronic toxicity of metsulfuron-methyl, nicosulfuron, methoxyfenozide were predicted using quantitative structure–activity relationship (QSAR) analysis through EPI Suite program. Furthermore, vivo testing was conducted evaluate skin irritation, eye sensitization based on modified OECD 404, 405, 406 guidelines. The QSAR indicated that all three pesticides have low profiles. irritation tests, metsulfuron-methyl (100 mg), nicosulfuron (125 (150 mg) showed a primary score 0 0, indicating no irritant effects rabbit guinea pig skin. test, caused mild conjunctival redness eyelid swelling, with an average 1.25, classifying it as (Category 2B). contrast, did not cause any observable 0. These findings suggest while may non-irritating do induce sensitization. This research provides essential toxicological data for regulatory evaluations underscores importance integrating methods assess pesticide comprehensively.

Language: Английский

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