Natural synthesis of β-glucan nanoparticles via microwave for breast cancer prevention: a study on oats-derived nanoparticles

Natural Product Research, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 7

Published: March 13, 2025

This study investigates the antibacterial and cancer-preventive properties of β-glucan nanoparticles (GNP) synthesised from oats using microwave energy, sodium tripolyphosphate (TPP), silver (Ag). UV-visible spectroscopy indicated a strong surface plasmon resonance peak between 220 250 nm for GNP. FTIR analysis identified band at 609 cm-1, signifying β linkage confirming presence β-glucans. SEM imaging showed that have smooth surfaces with various forms sizes ranging 67 to 129 nm, which aligns average size 76-115 determined by particle analysis. The disc diffusion method revealed significant activity GNP DNA fragmentation confirmed induced apoptosis in MCF-7 cell lines. observed IC50 value (50.41-59.34 µg/ml) dose effectively triggers highlighting their potent anticancer effects. selective cytotoxicity towards cancer cells emphasises need further exploration these targeted therapy.

Language: Английский

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Intracellular Production of Gold Nanoparticles from Lysinibacillus fusiformis, Their Spectro-Structural Characterization and Antibacterial Potential on MDR Bacteria of Chronic Wounds

BioNanoScience, Journal Year: 2025, Volume and Issue: 15(2)

Published: March 24, 2025

Language: Английский

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Directed Evolution of Silicatein Reveals Biomineralization Synergism between Protein Sequences

ACS Omega, Journal Year: 2025, Volume and Issue: 10(1), P. 334 - 343

Published: Jan. 6, 2025

Biomineralization is a green synthesis route for variety of metal nanoparticles. Silicatein biomineralization protein originally found in marine sponge Tethya aurantia that converts inorganic precursors to oxide In this work, we investigate the popular catalytic triad hypothesis and implement directed evolution with aim improve solubility kinetics silicatein enable increased nanoparticle synthesis. Site-directed mutagenesis residues did not abolish activity, aligning results seen one previous study. Recombinant production mutants Escherichia coli following library generation survival screen yielded several mutant proteins augmented activity. Sequence analysis these reveals multiple sequences within single cell contribute enhanced biomineralization. Combined sequence silicateins from different sponges, suggest permissive wide variations act synergistically

Language: Английский

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In Situ Self‐Assembled La and Y Nanoparticles Based on Biomineralization of Diatom Frustules to Boost the Electrochemical Performance of SiO₂ Anodes for Lithium‐Ion Batteries

Advanced Sustainable Systems, Journal Year: 2025, Volume and Issue: unknown

Published: March 27, 2025

Abstract Using diatoms, a typical microbial system of biomineralization, as template, La 2 O 3 and Y are synthesized in situ via biological self‐assembly during the cultivation diatoms 3+ /Y ‐containing media without any supplements, reducing agents or triggering agents. Then, diatom frustules modified with nanoparticles (NPs) prepared high‐temperature reduction crystallization. Furthermore, it has been used an anode material for lithium‐ion batteries excellent electrochemical properties. The DFT calculations reveal that doping changes energy band structure near Fermi level SiO increases current carrying density. frustule anodes loaded (DBS@C‐La‐10 DBS@C‐Y‐10) have specific discharge capacities approximately 1021.3 980.7 mAh g −1 , respectively, after 220 cycles. This is first study which mineralization behavior rare earth elements on reported applied to batteries. work provides new option applying field storage.

Language: Английский

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Bioinspired Nanomaterials to Combat Microbial Biofilm and Pathogen Challenges: A Review

ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: 7(22), P. 25287 - 25313

Published: Nov. 12, 2024

The emergence of antibiotic-resistant biofilms poses a significant challenge in healthcare, as these complex microbial communities demonstrate an increased resistance to conventional treatment methods. Traditional antibiotics often fail against biofilms, resulting persistent infections and failures. To address this urgent issue, innovative strategies such bioinspired nanomaterials, antimicrobial peptides, quorum sensing inhibitors, combination therapies show promise disrupting biofilm structures, enhancing activity, overcoming mechanisms. Bioinspired nanomaterials have emerged pivotal approach for tackling the challenges presented by pathogens across various sectors, including industry, environmental protection. Their advantages include enhanced biocompatibility, targeted delivery, improved efficacy formation threats. Recent advancements highlight potential solutions, nanoparticles, smart nanocarriers, surface modifications, nanozymes, combating biofilm-related issues. Despite progress nanomaterial research, remain. intricate interactions within evolving nature necessitate multidisciplinary approaches. Furthermore, translating laboratory findings into practical applications faces obstacles related scalability, stability, regulatory compliance. Future are expected focus on multifunctional nanoparticles that disrupt advanced modifications better interaction, nanocarriers nanozymes dismantle structures. This review focuses development application pathogen challenges. It emphasizes roles targeting capabilities. Additionally, explores formulating management practices, providing insights advantages, limitations, future perspectives

Language: Английский

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Mineralization of SF6 and NF3 fluorinated compounds for greenhouse gas abatement by oxalates

Chemosphere, Journal Year: 2024, Volume and Issue: 358, P. 142186 - 142186

Published: May 1, 2024

Language: Английский

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Lignin-Functionalized Fe₃O₄ Nanoparticles Facilitate the Extraction and Reduction of Metal Ions to Form Binary and Quinary Composite Nanoparticles

ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: 7(14), P. 16949 - 16963

Published: July 16, 2024

Lignin functionalized magnetic nanoparticles (NPs) were used for the interfacial biomineralization of Fe3O4–Au, Fe3O4–Ag, Fe3O4–Pd, Fe3O4–Pt binary, and Fe3O4–Au–Ag–Pd–Pt quinary nanocomposites in aqueous phase at room temperature. The weak reducing ability lignin adsorbed on solid–liquid interface NPs facilitated reduction extraction metal ions. It was controlled by availability surface-adsorbed lignols as well steric hindrances faced molecular geometry complex Interfacial synthesized pure Au, Ag, Pd conjunction with Fe3O4 to produce binary nanocomposites, whereas preferred reduce PtCl62– ions into PtO NPs. Quinary mainly constituted a combination Au–Ag–Pd–Pt alloy NPs, where autocatalytic stepwise manner. Energy dispersive X-ray spectroscopy (EDS) photoelectron (XPS) analyses determined elemental composition which placed amounts different order Au > Ag Pt. maximum minimum Pt, respectively, delicate balance between potential hindrances. Both strongly responded external field, thus facilitating their applicability phase.

Language: Английский

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Microbial Mineralization with Lysinibacillus sphaericus for Selective Lithium Nanoparticle Extraction

Environmental Science & Technology, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 12, 2024

Lithium is a critical mineral in wide range of current technologies, and demand continues to grow with the transition green economy. Current lithium mining extraction practices are often highly ecologically damaging, part due large amount water energy they consume. Biomineralization natural process that transforms inorganic precursors minerals. Microbial biomineralization has potential as an ecofriendly alternative techniques. This work demonstrates

Language: Английский

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A comprehensive review on biogenic metallic, metal oxide and metal sulfide nanoparticles for water treatment and sensing applications

Journal of Industrial and Engineering Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 1, 2024

Language: Английский

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Copper- and Iron-Based Nanoflowers in Cancer Theranostics

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(23), P. 11294 - 11294

Published: Dec. 4, 2024

In recent years, nanoscience and nanotechnology have gained prominence within materials science, offering new opportunities for cancer diagnosis treatment. Advances in allowed the manipulation size control of nanomaterials, leading to development a wide range materials. The use nanomaterials as chemical biology tools theranostics has been widely investigated, owing their enhanced stability, biocompatibility, improved cell permeability. These properties enable precise targeting while addressing limitations conventional treatments. Nanoflowers, specific class recently attracted significant interest due promising several biomedical applications. However, despite growing attention toward nanoflowers, detailed reviews on subject limited. This work focuses two primary types hybrid nanoflowers: iron- copper-based ones. Within this article an overview applications are thoroughly reviewed, synthesis processes controlling morphology size, underlying functions, characteristics uses also extensively explored, aiming provide guide future developments field.

Language: Английский

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