A Perspective on Polylactic Acid-Based Polymers Use for Nanoparticles Synthesis and Applications

Frontiers in Bioengineering and Biotechnology, Journal Year: 2019, Volume and Issue: 7

Published: Oct. 11, 2019

Polylactic acid (PLA) – based polymers are ubiquitous in the biomedical field thanks to their combination of attractive peculiarities: biocompatibility (degradation products do not elicit critical responses and easily metabolized by body), hydrolytic degradation situ, tailorable properties well–established processing technologies. This led development several applications, such as bone fixation screws, bioresorbable suture threads stent coating, just name a few. Nanomedicine could be unconcerned PLA–based materials well, where use for synthesis nanocarriers targeted delivery hydrophobic drugs emerged new promising application. The purpose here presented review is twofold: on one side, it aims at providing broad overview properties, which allow them gaining leading role field; other offers specific focus recent nanomedicine, highlighting opportunities perspectives.

Language: Английский

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Two-dimensional materials in biomedical, biosensing and sensing applications

Chemical Society Reviews, Journal Year: 2020, Volume and Issue: 50(1), P. 619 - 657

Published: Nov. 18, 2020

Two-dimensional (2D) materials are at the forefront of research. Here we overview their applications beyond graphene, such as transition metal dichalcogenides, monoelemental Xenes (including phosphorene and bismuthene), carbon nitrides, boron nitrides along with carbides (MXenes). We discuss usage in various biomedical environmental monitoring applications, from biosensors to therapeutic treatment agents, toxicity utility chemical sensing. highlight how a specific chemical, physical optical property 2D can influence performance bio/sensing, improve drug delivery photo/thermal therapy well affect toxicity. Such properties determined by crystal phases electrical conductivity, degree exfoliation, surface functionalization, strong photoluminescence, absorption near-infrared range high photothermal conversion efficiency. This review conveys great future all families materials, especially expanding materials' landscape new emerge germanene silicene.

Language: Английский

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Nanomaterials in the environment, human exposure pathway, and health effects: A review

The Science of The Total Environment, Journal Year: 2020, Volume and Issue: 759, P. 143470 - 143470

Published: Nov. 17, 2020

Language: Английский

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High‐Aspect‐Ratio Nanostructured Surfaces as Biological Metamaterials

Advanced Materials, Journal Year: 2020, Volume and Issue: 32(9)

Published: Jan. 16, 2020

Abstract Materials patterned with high‐aspect‐ratio nanostructures have features on similar length scales to cellular components. These surfaces are an extreme topography the level and become useful tools for perturbing sensing environment. Motivation comes from ability of deliver cargoes into cells tissues, access intracellular environment, control cell behavior. structures directly perturb cells' sense respond external forces, influencing fate, enabling new mechanistic studies. Through careful design their nanoscale structure, these systems act as biological metamaterials, eliciting unusual responses. While predominantly used interface eukaryotic cells, there is growing interest in nonanimal prokaryotic interfacing. Both experimental theoretical studies attempted develop a understanding observed behaviors, focusing cell–nanostructure interface. This review considers how nanostructured both stimulate systems.

Language: Английский

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Nanocarrier Drug Delivery Systems: Characterization, Limitations, Future Perspectives and Implementation of Artificial Intelligence

Pharmaceutics, Journal Year: 2022, Volume and Issue: 14(4), P. 883 - 883

Published: April 18, 2022

There has been an increasing demand for the development of nanocarriers targeting multiple diseases with a broad range properties. Due to their tiny size, giant surface area and feasible targetability, have optimized efficacy, decreased side effects improved stability over conventional drug dosage forms. are diverse types that synthesized delivery, including dendrimers, liposomes, solid lipid nanoparticles, polymersomes, polymer–drug conjugates, polymeric peptide micelles, nanoemulsions, nanospheres, nanocapsules, nanoshells, carbon nanotubes gold etc. Several characterization techniques proposed used past few decades control predict behavior both in vitro vivo. In this review, we describe some fundamental vitro, ex vivo, situ vivo methods most nanocarriers, emphasizing advantages limitations, as well safety, regulatory manufacturing aspects hinder transfer from laboratory clinic. Moreover, integration artificial intelligence nanotechnology, problems optimization also discussed, along future perspectives.

Language: Английский

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Toxicity of carbon-based nanomaterials: Reviewing recent reports in medical and biological systems

Chemico-Biological Interactions, Journal Year: 2019, Volume and Issue: 307, P. 206 - 222

Published: May 1, 2019

Language: Английский

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ZnO nanomaterials: Green synthesis, toxicity evaluation and new insights in biomedical applications

Journal of Alloys and Compounds, Journal Year: 2021, Volume and Issue: 876, P. 160175 - 160175

Published: May 4, 2021

Language: Английский

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Advanced Functional Nanostructures based on Magnetic Iron Oxide Nanomaterials for Water Remediation: A Review

Water Research, Journal Year: 2020, Volume and Issue: 190, P. 116693 - 116693

Published: Nov. 30, 2020

Language: Английский

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Cytotoxicity of MXene-based nanomaterials for biomedical applications: A mini review

Environmental Research, Journal Year: 2021, Volume and Issue: 201, P. 111592 - 111592

Published: June 25, 2021

Language: Английский

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Recent progress of fluorescent materials for fingermarks detection in forensic science and anti-counterfeiting

Coordination Chemistry Reviews, Journal Year: 2022, Volume and Issue: 462, P. 214523 - 214523

Published: March 25, 2022

Language: Английский

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