Advances of nanoparticles as drug delivery systems for disease diagnosis and treatment

Chinese Chemical Letters, Journal Year: 2022, Volume and Issue: 34(2), P. 107518 - 107518

Published: May 14, 2022

Language: Английский

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Two-dimensional nanomaterials: A critical review of recent progress, properties, applications, and future directions

Composites Part A Applied Science and Manufacturing, Journal Year: 2022, Volume and Issue: 165, P. 107362 - 107362

Published: Dec. 9, 2022

Language: Английский

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Carbon Dots in Bioimaging, Biosensing and Therapeutics: A Comprehensive Review

Small Science, Journal Year: 2022, Volume and Issue: 2(6)

Published: May 8, 2022

Carbon dots (CDs), comprising crystalline graphitized carbon cores and polymer surface groups, are currently attracting a lot of interest in biological fields owing to their fluorescent properties, high photostability, biocompatibility low toxicity. In addition, the easy preparation functionalization CDs stimulate development CDs‐based composite materials with specific functions. Presently, applications growing at remarkable speed, justifying need for up‐to‐date review articles that capture recent progress this blossoming field. review, breakthroughs synthesis, modification, optical toxicology biocatalytic platforms described. Further, research related bioimaging, biosensing, drug delivery, antibacterial, anticancer (photothermal therapy, photodynamic therapy synergistic therapy) antiviral therapies involving discussed detail. Finally, perspective on prospects challenges biomedicine biotechnology is provided.

Language: Английский

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Flexible Accelerated‐Wound‐Healing Antibacterial MXene‐Based Epidermic Sensor for Intelligent Wearable Human‐Machine Interaction

Advanced Functional Materials, Journal Year: 2022, Volume and Issue: 32(47)

Published: Sept. 17, 2022

Abstract Flexible epidermic sensors made from conductive hydrogels are holding bright potential in personalized healthcare, multifunctional electronic skins, and human‐machine interfaces. However, it is still a great challenge to simultaneously realize hydrogel‐based with reliable self‐healing ability remarkable sensing performances high‐performance healthcare (especially electrophysiological signals) for wearable interaction, as well accelerated wound healing subsequent medical treatment together. Herein, flexible healable sensor assembled the facilely prepared antibacterial MXene hydrogel efficiently sensitively interaction. The as‐prepared possesses enhanced mechanical performance, outstanding capability, injectability, facile degradability, excellent biocompatibility, robust ability, which capable of being into monitor human movements rehabilitation training, detect tiny signals diagnosis cardiovascular‐ muscle‐related diseases, be employed In addition, can utilized treat infection effectively accelerate healing. Thus, sheds light on preparing integration personal health smart interaction next‐generation artificial skins.

Language: Английский

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2D Material‐Based Optical Biosensor: Status and Prospect

Advanced Science, Journal Year: 2021, Volume and Issue: 9(4)

Published: Dec. 13, 2021

Abstract The combination of 2D materials and optical biosensors has become a hot research topic in recent years. Graphene, transition metal dichalcogenides, black phosphorus, MXenes, other (metal oxides degenerate semiconductors) have unique properties play role the detection different biomolecules. Through modification materials, biosensor advantages that traditional sensors (such as electrical sensing) do not have, sensitivity limit are greatly improved. Here, based on reviewed. First, various methods biomolecules, including surface plasmon resonance (SPR), fluorescence energy transfer (FRET), evanescent wave properties, preparation integration strategies material, introduced detail. Second, summarized. Furthermore, applications these biological imaging, food safety, pollution prevention/control, medicine discussed. Finally, future development is prospected. It believed with their in‐depth laboratory, will gradually commercialized improve people's quality life many aspects.

Language: Английский

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Nitrogen‐Enriched Conjugated Polymer Enabled Metal‐Free Carbon Nanozymes with Efficient Oxidase‐Like Activity

Small, Journal Year: 2021, Volume and Issue: 18(3)

Published: Nov. 27, 2021

Abstract Metal‐free carbon nanozymes could be promising with the unique features of intrinsic catalytic ability, structure diversity, and strong tolerance to acidic/alkaline media. However, date, study metal‐free fell far behind metal‐based nanomaterials, in which, majority reported much more peroxidase‐like activity than other enzyme‐mimicking behavior (e.g., oxidase). Thus, exploit high‐performance is importance but challenging. In this work, nitrogen‐rich conjugated polymer (Aza‐CPs) rigid network utilized as precursor yield N ‐doped material QAU‐Z1 high via a direct pyrolysis method. Surprisingly, stood out oxidase‐like behavior, which significantly outperformed control materials GNC‐900 QAU‐Z2 nucleobase or small molecule precursor, respectively. More importantly, it crucial revelation that performance closely related change zeta potential for nanozyme during substrate 3,3′,5,5′‐tetramethylbenzidine oxidation process, well its catalytical capacity O 2 , insightful understand inherent mechanism. This work not only presents polymers constructing highly efficient nanozyme, also reveals vital role interaction mode between performance.

Language: Английский

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MEMS Gas Sensors: A Review

IEEE Sensors Journal, Journal Year: 2021, Volume and Issue: 21(17), P. 18381 - 18397

Published: June 23, 2021

Micro-electromechanical system (MEMS) gas sensors represent a that is capable of detecting the existence and concentration gasses in atmosphere. These have become incredibly popular been widely used variety fields, including biomedical field. Over years, several developed to detect analyze wide range gases. As sensor applications are expected be further extended near future, it is, therefore, essential review crucial types sensors, their features, challenges, important applications. This paper presents comprehensive state-of-the-art which for sensing using MEMS technology. The working principle, structure, sensitive material characteristics each these discussed. focus this on surrounding use electrochemical, optical acoustic

Language: Английский

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Ti₃C₂MXene–polymer nanocomposites and their applications

Journal of Materials Chemistry A, Journal Year: 2021, Volume and Issue: 9(13), P. 8051 - 8098

Published: Jan. 1, 2021

Favorable interactions between polymer chains and Ti₃C₂MXene flakes are essential to develop state-of-the-art MXene/polymer nanocomposite devices.

Language: Английский

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Biomedical Applications of MXene‐Integrated Composites: Regenerative Medicine, Infection Therapy, Cancer Treatment, and Biosensing

Advanced Functional Materials, Journal Year: 2022, Volume and Issue: 32(34)

Published: June 24, 2022

Abstract MXenes (viz., transition metal carbides, carbonitrides, and nitrides) have emerged as a new subclass of 2D materials. Due to their outstanding physicochemical biological properties, gained much attention in the biomedical field recent years, including drug delivery systems, regenerative medicine, biosensing. Additionally, incorporation into hydrogels has garnered significant interest engineering an electroactive mechanical nanoreinforcer capable converting nonconductive scaffolds excellent conductors electricity with impressive effect on properties for organs tissues such cardiac, skeletal muscle, nerve. However, many questions problems remain unresolved that need be answered usher these materials toward true destiny. Thus, this review paper aims provide overview design applications MXene‐integrated composites applications, cardiac tissue engineering, wound healing, infection therapy, cancer biosensors. Moreover, current challenges limitations utilizing vivo are highlighted discussed, followed by its prospects guideline possible various futuristic applications. This article will inspire researchers, who search opportunities, using nanomaterial

Language: Английский

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Wearable sensors for telehealth based on emerging materials and nanoarchitectonics

npj Flexible Electronics, Journal Year: 2023, Volume and Issue: 7(1)

Published: June 2, 2023

Abstract Wearable sensors have made significant progress in sensing physiological and biochemical markers for telehealth. By monitoring vital signs like body temperature, arterial oxygen saturation, breath rate, wearable provide enormous potential the early detection of diseases. In recent years, advancements been achieved development based on two-dimensional (2D) materials with flexibility, excellent mechanical stability, high sensitivity, accuracy introducing a new approach to remote real-time health monitoring. this review, we outline 2D materials-based biosensors system. The review focused five types sensors, which were classified according their mechanism, such as pressure, strain, electrochemical, optoelectronic, temperature sensors. material capabilities impact performance operation sensor are outlined. fundamental principles mechanism well applications explored. This concludes by discussing remaining obstacles future opportunities emerging telehealth field. We hope that report will be useful individuals who want design it generate ideas.

Language: Английский

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