Chemistry - A European Journal,
Journal Year:
2023,
Volume and Issue:
30(7)
Published: Nov. 13, 2023
We
present
an
in-depth
study
of
the
sterically
demanding
Cp-synthon
(8-H-GuaH)Li
isolated
from
natural
product
guaiazulene
(Gua)
as
a
ligand
transfer
reagent
towards
late
transition
metal
complex
precursors.
The
synthesis
and
full
characterization
selected,
essentially
unexplored
homo-
heteroleptic
8-H-guaiazulenide
complexes
iron,
ruthenium,
cobalt,
rhodium,
platinum,
copper
zinc
are
discussed
in
detail.
In
order
to
demonstrate
their
potential
catalytic
applications,
[(GuaH)PtMe
Chemical Communications,
Journal Year:
2024,
Volume and Issue:
60(33), P. 4491 - 4494
Published: Jan. 1, 2024
The
enantiomers
of
an
arene
ruthenium
complex
were
separated
by
chromatography
using
auxiliary
chiral
phosphine.
resolved
planar-chiral
catalyzed
asymmetric
C–H
activation
N
-methoxy-benzamides.
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(49), P. 8906 - 8911
Published: Dec. 5, 2023
A
simple
four-step
route
to
a
chiral
tetrahydrofluorenyl
rhodium
catalyst
from
naturally
occurring
(−)-α-pinene
was
developed.
Our
approach
does
not
use
multistep
and
time-consuming
procedures
such
as
HPLC
or
diastereomeric
resolution.
The
key
success
lies
in
the
face-selective
coordination
of
sterically
hindered
ligand,
giving
only
one
complex.
This
proved
be
highly
efficient
for
asymmetric
C–H
annulation
aryl
hydroxamates
with
alkenes
(yield
up
95%,
91%
ee)
at
low
loading
(up
0.4
mol
%
based
on
Rh).
Angewandte Chemie International Edition,
Journal Year:
2024,
Volume and Issue:
63(32)
Published: May 23, 2024
Abstract
Development
of
chiral
indenyl
ligands
for
asymmetric
C−H
activation
is
a
longstanding
challenge,
and
extremely
few
successes
have
been
achieved.
In
this
paper,
we
describe
class
readily
accessible,
facilely
tunable
user‐friendly
featuring
[2.2]benzoindenophane
skeleton
via
divergent
synthesis
strategy.
The
corresponding
rhodium
catalysts
were
successfully
applied
in
the
reaction
O‐Boc
hydroxybenzamide
with
alkenes
to
give
various
dihydroisoquinolone
products
(up
97
%
yield,
up
98
ee).
Moreover,
carboxylic
acids
alkynes
was
also
accomplished,
providing
range
axially
isocoumarins
99
94
Notably,
represents
first
example
enantioselective
transition
metal
catalyzed
C(sp
2
)−H
activation/oxidative
coupling
benzoic
internal
construct
isocoumarins.
Given
many
attractive
features
ligands,
such
as
convenient
synthesis,
high
tunability
exclusive
face‐selectivity
coordination,
its
applications
more
catalytic
other
catalysis
are
foreseen.
Advanced Synthesis & Catalysis,
Journal Year:
2024,
Volume and Issue:
366(5), P. 1064 - 1069
Published: Jan. 13, 2024
Abstract
We
report
herein
a
chiral
Cp
X
Rh(III)‐catalyzed
domino
cyclization/C
3
‐arylation
process
using
2‐alkynylanilines
and
1‐diazonaphthoquinones
as
viable
substrates,
delivering
indole‐based
derivatives
endowed
with
axial
chirality.
The
method
features
high
enantioselectivity,
broad
substrate
scope,
robust
functional
group
tolerance.
Subsequent
functionalization
of
the
synthesized
scaffolds
underlines
practicality
this
approach
in
design
indole‐derivated
axially
frameworks,
demonstrating
its
substantial
promise
synthetic
medicinal
chemistry
applications.
The Journal of Physical Chemistry Letters,
Journal Year:
2024,
Volume and Issue:
15(30), P. 7740 - 7747
Published: July 24, 2024
Chiral
plasmonic
nanostructures
exhibit
potential
in
the
advanced
manufacturing
industry,
due
to
their
fascinating
characteristics.
However,
limitation
of
existing
fabrication
methods
as
difficulty
precisely
manipulate
chiral
at
nanoscale
restricts
application
and
optimization
performance.
In
this
work,
we
report
a
simple
robust
route
for
precise
construction
Au
nanoparticles
(NPs),
employing
star-like
block
copolymers
with
well-defined
structures
templates.
The
globular
unimolecular
micelles
nanoreactors
enabled
control
over
size,
shape,
chirality
situ
grown
nanocrystals.
Utilizing
anisotropy
property
surface-enhanced
Raman
scattering
(SERS),
enantioselective
discrimination
on
various
substrates
was
accomplished
an
enhancement
factor
9.3
×
106.
NPs
smaller
size
exhibited
strengthened
recognition.
Furthermore,
these
unimolecular-micelle-based
templates
high
efficiency
strong
controllability
could
pave
way
tailor-made
nanomaterials.
Journal of the American Chemical Society,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 18, 2024
Owing
to
substantial
advances
in
the
past
several
decades,
transition-metal-catalyzed
asymmetric
reactions
have
garnered
considerable
attention
as
pivotal
methods
for
constructing
chiral
molecules
from
abundant,
readily
available
achiral
counterparts.
These
are
largely
attributed
development
of
ligands
that
control
stereochemistry
through
steric
repulsion
and
other
noncovalent
interactions
between
functional
groups
or
prochiral
centers
on
substrates.
However,
stereocontrol
weakens
dramatically
with
increasing
distance
reaction
site
group
center.
Herein,
we
report
a
symphonic
strategy
remote
Rh(III)-catalyzed
benzylic
C-H
bond
addition
diarylmethanes
which
two
aryl
motifs
differ
at
Dalton Transactions,
Journal Year:
2023,
Volume and Issue:
52(45), P. 17005 - 17010
Published: Jan. 1, 2023
Rhodium
complexes
with
various
planar-chiral
cyclopentadienyl
ligands
were
synthesized
in
1–3
steps
by
the
unusual
2
+
1-cyclotrimerization
of
tert
-butylacetylene.
Angewandte Chemie,
Journal Year:
2024,
Volume and Issue:
136(32)
Published: May 23, 2024
Abstract
Development
of
chiral
indenyl
ligands
for
asymmetric
C−H
activation
is
a
longstanding
challenge,
and
extremely
few
successes
have
been
achieved.
In
this
paper,
we
describe
class
readily
accessible,
facilely
tunable
user‐friendly
featuring
[2.2]benzoindenophane
skeleton
via
divergent
synthesis
strategy.
The
corresponding
rhodium
catalysts
were
successfully
applied
in
the
reaction
O‐Boc
hydroxybenzamide
with
alkenes
to
give
various
dihydroisoquinolone
products
(up
97
%
yield,
up
98
ee).
Moreover,
carboxylic
acids
alkynes
was
also
accomplished,
providing
range
axially
isocoumarins
99
94
Notably,
represents
first
example
enantioselective
transition
metal
catalyzed
C(sp
2
)−H
activation/oxidative
coupling
benzoic
internal
construct
isocoumarins.
Given
many
attractive
features
ligands,
such
as
convenient
synthesis,
high
tunability
exclusive
face‐selectivity
coordination,
its
applications
more
catalytic
other
catalysis
are
foreseen.
