A novel electrocatalyst based on NiO@C-dot nanocomposites for sensitive determination of ophthalmic drugs

Alexandria Engineering Journal, Journal Year: 2024, Volume and Issue: 105, P. 655 - 665

Published: Aug. 23, 2024

Language: Английский

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Synthesis, physicochemical characterisation of novel Azo-2-{[(E)-{2-hydroxy-3-methoxy-5-[(E)-(4-nitrophenyl)diazenyl]phenyl}methylidene]amino}pyridin-3-ol and its metal complexes; evaluation of anti-diabetic, anti-tuberculosis, DFT, Docking and Electrochemical detection of pain relief Paracetamol

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: 1322, P. 140461 - 140461

Published: Oct. 31, 2024

Language: Английский

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Design and optimization of WSe₂@NiCo-MOF for dual-mode applications: energy storage and chemosensing

Physica Scripta, Journal Year: 2024, Volume and Issue: 99(12), P. 125992 - 125992

Published: Nov. 14, 2024

Abstract Metal–organic frameworks have accomplished significant consideration in energy stroage devices (ESDs) owing to their adjustable pore structure and substantial specific surface area. Herein, NiCo-MOF was synthesized using the hydrothermal method at a temperature of 150 °C, WSe 2 tip sonication method. The /NiCo-MOFs electrode showed an outstanding capacity (Cs) 1053.65 C/g. /NiCo-MOFs//AC asymmetric device revealed remarkable Cs 270.5 acquired power density (P d ) 1791.4 W kg −1 (E 38.8 Wh , demonstrating its exceptional performance. Furthermore, /NiCo-MOF//AC retained 86.7% retention after 5,000 cycles durability test. Metal ion sensors find utility environmental assessments, medical diagnostics, industrial procedures. Strontium is essential alkaline earth metal, constituting approximately 0.02 0.03% Earth’s crust. These nanoparticle-based chemosensor potential be highly accurate precise detection metal ions, which promising incentive for advancement. /NiCo-MOF photoelectrode demonstrated photoactivity, quick reaction recovery times, good photo-switching Saturation attained, fluorescence spectra were taken periods three different molar concentrations strontium ions (10 M, 20 50 M). multifunctional nanocomposite material can used design hybrid harvesting devices.

Language: Английский

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Novel application of carbon nanotube electrodes for electrochemical detection of amino acids in athlete’s biological samples

Alexandria Engineering Journal, Journal Year: 2024, Volume and Issue: 108, P. 221 - 231

Published: July 30, 2024

Language: Английский

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Synthesis and In Silico Evaluation of Piperazine-Substituted 2,3-Dichloro-5,8-dihydroxy-1,4-naphthoquinone Derivatives as Potential PARP-1 Inhibitors

ACS Omega, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 10, 2024

PARP-1 (poly(ADP-ribose)-polymerase 1) inhibitors are vital in synthetic lethality, primarily due to their specificity for over PARP-2 (PARP-1 > PARP-2). This is crucial as it allows precise inhibition of tumor cells with Breast Cancer 1 protein (BRCA1) or BRCA2 deficiencies. The development highly specific not only meets the therapeutic needs treatment but also has potential minimize adverse effects associated nonselective inhibition. In this study, a series novel 2,3-dichloro-5,8-dihydroxy-1,4-naphthoquinone (DDNO) derivatives were synthesized, characterized, and evaluated regarding inhibitory cytotoxic activity. Compound 3 exhibited highest against all cell lines, except MDA-MB-231 cells. these molecules was through silico molecular docking dynamics studies. Notably, compounds

Language: Английский

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DFT study of adsorption and potential detection of carbonyl fluoride on B-doped aluminum nitride nanosheets

Applied Surface Science, Journal Year: 2024, Volume and Issue: unknown, P. 161285 - 161285

Published: Sept. 1, 2024

Language: Английский

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Iron-iridium metal organic framework/nitrogen doped MXene/graphene quantum dots: A leading composite for electrolytic energy storage and hydrogen evolution reaction

Diamond and Related Materials, Journal Year: 2024, Volume and Issue: 149, P. 111653 - 111653

Published: Oct. 12, 2024

Language: Английский

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Efficient synthesis of β-aminonitriles from arynes and imines in acetonitrile

RSC Advances, Journal Year: 2024, Volume and Issue: 14(46), P. 33747 - 33750

Published: Jan. 1, 2024

Two new bonds (C–C and C–N) are formed in one step without metal catalysts showing the potential of this transformation.

Language: Английский

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Investigating the Tyrosinase Inhibitory Activity of 4‐Bromobenzoic Acid Hydrazone‐Schiff Bases: In Vitro, Molecular Structure and Docking Studies

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(44)

Published: Nov. 1, 2024

Abstract Fourteen hydrazone‐Schiff base derivatives bearing 4‐bromobenzoic acid have been successfully synthesized, characterized by means of 1 H‐NMR and EI‐MS spectrometry finally evaluated for in vitro tyrosinase inhibitory activity. Among the series, five compounds 2 g , k d c n attributed potent inhibitors with IC 50 values ranging from (IC =6.07±0.40 μM) to =13.15±0.09 surpassing standard drug kojic =16.9±1.30 μM). Furthermore, remaining demonstrated significant less inhibition. The density functional theory (DFT) study was performed investigate various electronic properties such as geometry optimization, global reactivity parameter, frontier molecular orbitals (FMOs), electrostatic potential map (MEPM), theoretical chemical shift, nonlinear optical (NLO). Theoretical shows good agreement experimental NLO analysis suggest that targeted are candidates optics. docking studies were executed on synthesized order explain binding interface active sites enzyme. observed current work may lead them promising future development.

Language: Английский

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Quantification of L-lactic acid in Human Plasma Samples using Ni-based Electrodes and Machine Learning Approach

Talanta, Journal Year: 2024, Volume and Issue: 286, P. 127493 - 127493

Published: Dec. 31, 2024

Language: Английский

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