Aerobic Oxidative Functionalization of Indoles

Advanced Synthesis & Catalysis, Journal Year: 2020, Volume and Issue: 362(18), P. 3795 - 3823

Published: May 18, 2020

Abstract The synthetic methodology for direct indole functionalizations is of great significance in chemistry and has been intensively investigated the last few decades. From perspective green chemistry, oxygen best choice as terminal oxidant molecular synthesis. Hence, aerobic oxidative functionalization indoles became a hot research topic decade. Numerous efficient protocols this field have discovered that enable facile transformations to related valuable compounds, which are summarized discussed detail review. magnified image

Language: Английский

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Iridium supported on porous polypyridine-oxadiazole as high-activity and recyclable catalyst for the borrowing hydrogen reaction

Green Chemistry, Journal Year: 2022, Volume and Issue: 24(6), P. 2602 - 2612

Published: Jan. 1, 2022

Porous polypyridine-oxadiazole supported iridium catalysts (PPO-Ir) revealed high catalytic activity for the reaction of dimethyl-6-aminouracil (including 1,3-dimethylbarbituric acid, 2-aminobenzylamine) with alcohols.

Language: Английский

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MOF-Derived Nanocobalt for Oxidative Functionalization of Cyclic Amines to Quinazolinones with 2-Aminoarylmethanols

ACS Catalysis, Journal Year: 2018, Volume and Issue: 8(7), P. 5869 - 5874

Published: May 25, 2018

By employing a MOF-templated method, we have developed highly dipersed and ultralow loading cobalt nanocatalyst, which has been applied in the oxidative functionalization of easily available cyclic amines with 2-aminoarylmethanols to ring-fused quinazolinones, core structures numerous valuable products. The catalytic transformation proceeds merits broad substrate scope, good functional group tolerance chemoselectivity, high step- atom-efficiency, use naturally abundant Co/O2 system, offers practical way for preparation quinazolinones structural diversity. work presented built an important basis direct conversion amine motifs into frameworks.

Language: Английский

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Recent advances in the Rh-catalyzed cascade arene C–H bond activation/annulation toward diverse heterocyclic compounds

Organic & Biomolecular Chemistry, Journal Year: 2021, Volume and Issue: 19(8), P. 1705 - 1721

Published: Jan. 1, 2021

A review highlighting the advances in Cp*Rh(iii) catalysed cascade arene C–H activation/annulation including application, scope, limitations and mechanism of these transformations.

Language: Английский

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Cu-Catalyzed Radical Cascade Annulations of Alkyne-Tethered N-Alkoxyamides with Air: Facile Access to Isoxazolidine/1,2-Oxazinane-Fused Isoquinolin-1(2H)-ones

ACS Catalysis, Journal Year: 2018, Volume and Issue: 8(9), P. 8925 - 8931

Published: Aug. 21, 2018

A series of structurally important isoxazolidine/1,2-oxazinane-fused isoquinolin-1(2H)-ones have been facilely synthesized via efficient Cu-catalyzed aerobic oxidative radical cascade annulations alkyne-tethered N-alkoxyamides. This method features air as the environment-friendly oxidant and has merits a cheap catalyst, broad substrates scope, high atom economy, simple operation.

Language: Английский

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MOF-Derived Subnanometer Cobalt Catalyst for Selective C–H Oxidative Sulfonylation of Tetrahydroquinoxalines with Sodium Sulfinates

ACS Catalysis, Journal Year: 2019, Volume and Issue: 9(4), P. 2718 - 2724

Published: Feb. 13, 2019

The development and utilization of reusable base-metal catalysts is a central topic in catalysis. Herein, via catalyst design strategy, we present the preparation highly dispersed acid-resistant subnanometer cobalt (<1 nm) by MOF-templated method, which has been utilized for selective C–H oxidative sulfonylation tetrahydroquinoxalines with odorless sodium sulfinates. transformation enables generation variety sulfonylquinoxalines merits good substrate functional group compatibility, high regio- chemoselectivity, use naturally abundant metal catalyst. work presented offers potential further heterogeneous nanocatalysts fabrication products that are difficult to prepare or inaccessible homogeneous

Language: Английский

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Straightforward access to novel indolo[2,3-b]indoles via aerobic copper-catalyzed [3+2] annulation of diarylamines and indoles

Chemical Communications, Journal Year: 2020, Volume and Issue: 56(18), P. 2807 - 2810

Published: Jan. 1, 2020

Unprecedented direct access to novel 2-diarylaminoindolo[2,3-b]indoles via aerobic copper-catalyzed [3+2] annulation of diarylamines and indoles is demonstrated.

Language: Английский

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Copper–iodine co-catalyzed C–H aminoalkenylation of indoles via temperature-controlled selectivity switch: facile synthesis of 2-azolyl-3-alkenylindoles

Organic Chemistry Frontiers, Journal Year: 2022, Volume and Issue: 9(14), P. 3794 - 3799

Published: Jan. 1, 2022

An efficient copper–iodine co-catalyzed 2,3-difunctionalization of indoles with azoles and phenols via temperature-controlled selectivity switch has been developed for the green synthesis 2-azolyl-3-alkenylindoles.

Language: Английский

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Green synthesis of benzimidazoles via the palladium catalyzed one-pot reductive coupling of nitroarylamines with nitriles

Journal of Molecular Structure, Journal Year: 2025, Volume and Issue: unknown, P. 141747 - 141747

Published: Feb. 1, 2025

Language: Английский

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A sustainable oxidative esterification of thiols with alcohols by a cobalt nanocatalyst supported on doped carbon

Green Chemistry, Journal Year: 2018, Volume and Issue: 20(9), P. 1992 - 1997

Published: Jan. 1, 2018

With a newly developed cobalt nanocatalyst using N–SiO₂-doped activated carbon as the support (Co/N–SiO₂–AC), sustainable oxidative esterification of (hetero)aryl and alkyl thiols with alcohols has been developed.

Language: Английский

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