A divergent construction of fused and bridged carbo-/heterocyclic scaffoldsviacascade reactions of aryl azomethine imines with vinyl cyclic carbonates DOI

Xinyuan Cai,

Xia Song,

Xueying Yang

et al.

Organic Chemistry Frontiers, Journal Year: 2023, Volume and Issue: 10(4), P. 1015 - 1021

Published: Jan. 1, 2023

Presented herein is a divergent synthesis of indene-fused pyrazoles and bridged benzodiazepines tethered with hydroxymethyl group through the cascade reactions aryl azomethine imines vinyl cyclic carbonates.

Language: Английский

Cobalt(iii)-catalyzed redox-neutral [4+2]-annulation of N-chlorobenzamides/acrylamides with alkylidenecyclopropanes at room temperature DOI

Balu Ramesh,

Masilamani Jeganmohan

Chemical Communications, Journal Year: 2021, Volume and Issue: 57(30), P. 3692 - 3695

Published: Jan. 1, 2021

An efficient synthesis of substituted 3,4-dihydroisoquinolinones through [4+2]-annulation N-chlorobenzamides/acrylamides with alkylidenecyclopropanes using a less expensive and air stable Co(iii) catalyst is demonstrated.

Language: Английский

Citations

31
Chiral Ligands Based on Binaphthyl Scaffolds for Pd-Catalyzed Enantioselective C–H Activation/Cycloaddition Reactions DOI Creative Commons
José Manuel González, Xandro Vidal, Manuel Á. Ortuño

et al.

Journal of the American Chemical Society, Journal Year: 2022, Volume and Issue: 144(47), P. 21437 - 21442

Published: Nov. 15, 2022

We report the first examples of use a new class ligands (NOBINAc) for performing asymmetric C-H activations using palladium catalysts. These combine axial chirality binaphthyl scaffolds with bifunctional and bidentate coordination properties mono-N-protected amino acids (MPAAs), which are well-known to favor Pd-promoted via concerted metalation-deprotonation mechanisms. demonstrate that our enable substantially higher enantioselectivities than MPAAs in assembly 2-benzazepines through formal (5 + 2) cycloadditions between homobenzyltriflamides or o-methylbenzyltriflamides allenes.

Language: Английский

Citations

20
Cyclopropenes and methylenecyclopropanes in 1,3-dipolar cycloaddition reactions DOI

А. П. Молчанов,

Мария М. Ефремова, Михаил А. Кузнецов

et al.

Russian Chemical Bulletin, Journal Year: 2022, Volume and Issue: 71(4), P. 620 - 650

Published: April 1, 2022

Language: Английский

Citations

19
Stereoselective construction of azepine-containing bridged scaffolds via organocata-lytic bicyclization of yne-allenone esters with nitrones DOI

Mengfan Li,

Shaoqing Shi, Ting Xu

et al.

Chinese Chemical Letters, Journal Year: 2022, Volume and Issue: 34(4), P. 107751 - 107751

Published: Aug. 23, 2022

Language: Английский

Citations

19
A divergent construction of fused and bridged carbo-/heterocyclic scaffoldsviacascade reactions of aryl azomethine imines with vinyl cyclic carbonates DOI

Xinyuan Cai,

Xia Song,

Xueying Yang

et al.

Organic Chemistry Frontiers, Journal Year: 2023, Volume and Issue: 10(4), P. 1015 - 1021

Published: Jan. 1, 2023

Presented herein is a divergent synthesis of indene-fused pyrazoles and bridged benzodiazepines tethered with hydroxymethyl group through the cascade reactions aryl azomethine imines vinyl cyclic carbonates.

Language: Английский

Citations

12