State-of-the-art developments in carbon quantum dots (CQDs): Photo-catalysis, bio-imaging, and bio-sensing applications

Chemosphere, Journal Year: 2022, Volume and Issue: 302, P. 134815 - 134815

Published: May 4, 2022

Language: Английский

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The Emerging Development of Multicolor Carbon Dots

Small, Journal Year: 2022, Volume and Issue: 18(51)

Published: Nov. 3, 2022

Abstract As a relatively new type of fluorescent carbon‐based nanomaterials, multicolor carbon dots (MCDs) have attracted much attention because their excellent biocompatibility, tunable photoluminescence (PL), high quantum yield, and unique electronic physicochemical properties. The emission characteristics (CDs) obviously depend on the source precursor, reaction conditions, environment, which directly or indirectly determines CDs. Therefore, this review is first systematic classification summary multiple regulation methods synthetic MCDs reviews recent research progress in synthesis from variety precursor materials such as aromatic molecules, small organic natural biomass, focusing how different produce corresponding MCDs. This also introduces innovative applications fields biological imaging, light‐emitting diodes (LEDs), sensing, anti‐counterfeiting due to PL It hoped that by selecting appropriate adjustment methods, can inspire guide future design tailored MCDs, provide help for development multifunctional

Language: Английский

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Carbon-Based Materials in Photodynamic and Photothermal Therapies Applied to Tumor Destruction

International Journal of Molecular Sciences, Journal Year: 2021, Volume and Issue: 23(1), P. 22 - 22

Published: Dec. 21, 2021

Within phototherapy, a grand challenge in clinical cancer treatments is to develop simple, cost-effective, and biocompatible approach treat this disease using ultra-low doses of light. Carbon-based materials (CBM), such as graphene oxide (GO), reduced GO (r-GO), quantum dots (GQDs), carbon (C-DOTs), are rapidly emerging new class therapeutic against cancer. This review summarizes the progress made recent years regarding applications CBM photodynamic (PDT) photothermal (PTT) therapies for tumor destruction. The current understanding performance modified CBM, hybrids composites, also addressed. seeks achieve an enhanced antitumor action by improving modulating properties various types Metal oxides, organic molecules, biopolymers, drugs, among others, have been combined with PDT, PTT, or synergistic therapies.

Language: Английский

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Electron–phonon coupling-assisted universal red luminescence of o-phenylenediamine-based carbon dots

Light Science & Applications, Journal Year: 2022, Volume and Issue: 11(1)

Published: June 6, 2022

Abstract Due to the complex core–shell structure and variety of surface functional groups, photoluminescence (PL) mechanism carbon dots (CDs) remain unclear. o-Phenylenediamine (oPD), as one most common precursors for preparing red emissive CDs, has been extensively studied. Interestingly, emission CDs based on oPD have similar PL characteristics. Herein, we prepared six different oPD-based found that they had almost same absorption spectra after purification. Structural spectral characterization indicated core structures but polymer shells. Furthermore, single-molecule spectroscopy confirmed multi-modal those originated from transitions vibrational energy levels center in core. In addition, phenomenon “spectral splitting” single-particle was observed at low temperature, which these were unique materials with properties both organic molecules quantum dots. Finally, theoretical calculations revealed their potential polymerization mode structure. Moreover, proposed red-emitting precursors; is, regulates emission, shell intensity. Our work resolves controversy CDs. These findings provide a general guide exploration structural analysis other types

Language: Английский

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Optical Properties of Carbon Dots in the Deep‐Red to Near‐Infrared Region Are Attractive for Biomedical Applications

Small, Journal Year: 2021, Volume and Issue: 17(43)

Published: Aug. 8, 2021

Carbon dots (CDs) represent a recently emerged class of luminescent materials with great potential for biomedical theranostics, and there are lot efforts to shift their absorption emission toward deep-red (DR) near-infrared (NIR) region falling in the biological transparency window. This review offers comprehensive insights into synthesis strategies aimed achieve this goal, current approaches modulating optical properties CDs over DR NIR region. The underlying mechanisms absorption, photoluminescence, chemiluminescence, as well related photophysical processes photothermal conversion formation reactive oxygen species considered. already available applications CDs, such photoacoustic imaging therapy, photodynamic use bioimaging agents drug carriers then shortly summarized.

Language: Английский

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Carbon Dot Therapeutic Platforms: Administration, Distribution, Metabolism, Excretion, Toxicity, and Therapeutic Potential

Small, Journal Year: 2022, Volume and Issue: 18(16)

Published: Jan. 27, 2022

Abstract Ultrasmall nanoparticles are often grouped under the broad umbrella term of “nanoparticles” when reported in literature. However, for biomedical applications, their small sizes give them intimate interactions with biological species and endow unique functional physiochemical properties. Carbon quantum dots (CQDs) an emerging class ultrasmall which have demonstrated considerable biocompatibility been employed as potent theragnostic platforms. These particles find application increasing drug solubility targeting, along facilitating passage drugs across impermeable membranes (i.e., blood brain barrier). Further functionality can be triggered by various environmental conditions or external stimuli pH, temperature, near Infrared (NIR) light, ultrasound), intrinsic fluorescence is valuable diagnostic applications. The focus this review to shed light on therapeutic potential CQDs identify how they travel through body, reach site action, administer effect, excreted. Investigation into toxicity compatibility larger nanoparticle carriers also examined. future applications promising due multifunctional attributes documented biocompatibility. As nanomaterial platforms become more commonplace clinical treatments, commercialization CQD therapeutics anticipated.

Language: Английский

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Green Carbon Dots: Synthesis, Characterization, Properties and Biomedical Applications

Journal of Functional Biomaterials, Journal Year: 2023, Volume and Issue: 14(1), P. 27 - 27

Published: Jan. 2, 2023

Carbon dots (CDs) are a new category of crystalline, quasi-spherical fluorescence, "zero-dimensional" carbon nanomaterials with spatial size between 1 nm to 10 and have gained widespread attention in recent years. Green CDs synthesised from renewable biomass such as agro-waste, plants or medicinal other organic biomaterials. Plant-mediated synthesis is green chemistry approach that connects nanotechnology the CDs. Notably, made technology economical far superior those manufactured physicochemical methods due their exclusive benefits, being affordable, having high stability, simple protocol, safer eco-benign. can be synthesized by using ultrasonic strategy, chemical oxidation, carbonization, solvothermal hydrothermal processes, microwave irradiation various plant-based resources. diverse applications biomedical fields bioimaging, biosensing nanomedicine, which ascribed unique properties, including excellent luminescence effect, strong stability good biocompatibility. This review mainly focuses on synthesis, characterization techniques, beneficial properties plant resource-based applications. article also looks at research gaps future directions for continuous deepening exploration

Language: Английский

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Carbon dots supported single Fe atom nanozyme for drug-resistant glioblastoma therapy by activating autophagy-lysosome pathway

Nano Today, Journal Year: 2022, Volume and Issue: 45, P. 101530 - 101530

Published: June 22, 2022

Language: Английский

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Formation and fluorescent mechanism of red emissive carbon dots from o-phenylenediamine and catechol system

Light Science & Applications, Journal Year: 2022, Volume and Issue: 11(1)

Published: Oct. 13, 2022

Carbon dots (CDs) as the advancing fluorescent carbon nanomaterial have superior potential and prospective. However, ambiguous photoluminescence (PL) mechanism intricate structure-function relationship become greatest hindrances in development applications of CDs. Herein, red emissive CDs were synthesized high yield from o-phenylenediamine (oPD) catechol (CAT). The PL is considered molecular state fluorophores because 5,14-dihydroquinoxalino[2,3-b] phenazine (DHQP) separated exhibits same properties behavior These include peak position shape emission excitation dependence on pH solvent polarity. Both them display close lifetime decays. Based these, we deduce that DHQP fluorophore similar to DHQP. During CDs, electron molecule can transfer formation process further confirmed by reaction intermediates (phthalazine, dimers) oPD. findings provide insights into this type may guide tunable for tailored properties.

Language: Английский

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Aggregation and luminescence in carbonized polymer dots

Aggregate, Journal Year: 2022, Volume and Issue: 3(2)

Published: Jan. 20, 2022

Abstract The aggregate luminescence behavior of organic luminescent materials has been studied extensively. As a new kind nanomaterials, carbonized polymer dots (CPDs) not only inherit the stability and biocompatibility carbon materials, but also possess tunability, water solubility, high photoluminescence quantum yield rendering them strong candidate for next generation light‐emitting materials. Previously, people mainly understood its from perspective some mechanisms are still unclear. In this review, we discuss mechanism by referring to with emphasis on their aggregation behavior. Firstly, three representative phenomena briefly introduced. Chromophores present in CPDs elaborated further potential interactions between them, role crosslinked networks. On basis, special state summarized, relevant discussed detail consolidate statements.

Language: Английский

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